{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Toothbrushing+only&page=2",
    "query": {
      "intervention": "Toothbrushing only",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Toothbrushing+only&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T02:24:22.688Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01283490",
      "title": "The Effect of Sonophoresis on Topical Anesthesia: A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Topical Anesthetic Applied With Sonophoresis"
      ],
      "interventions": [
        {
          "name": "DASD Group",
          "type": "DEVICE"
        },
        {
          "name": "Sonic Vibration (SV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 50,
      "start_date": "2011-02",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2016-11-21",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01283490"
    },
    {
      "nct_id": "NCT03219840",
      "title": "Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingivitis",
        "Plaque, Dental",
        "Periodontal Diseases"
      ],
      "interventions": [
        {
          "name": "Cetylpyridinium Chloride (CPC) 0.09% + Xylitol chewing gum",
          "type": "DRUG"
        },
        {
          "name": "Xylitol only chewing gum",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2017-10-18",
      "completion_date": "2018-09-08",
      "has_results": true,
      "last_update_posted_date": "2021-02-08",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03219840"
    },
    {
      "nct_id": "NCT07810868",
      "title": "Effectiveness of Ortho-Buddy on Plaque Control in Orthodontic Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthodontic Patients With Fixed Appliances"
      ],
      "interventions": [
        {
          "name": "Standard Toothbrush",
          "type": "DEVICE"
        },
        {
          "name": "Ortho-Buddy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "11 Years to 18 Years"
      },
      "enrollment_count": 48,
      "start_date": "2022-05-18",
      "completion_date": "2024-11-04",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07810868"
    },
    {
      "nct_id": "NCT07711301",
      "title": "The Science Tooth Fairy: A Randomized Trial of a Storytelling-Based Educational Intervention to Promote Primary Tooth Donation in a Pediatric Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Health Knowledge, Attitudes, Practices"
      ],
      "interventions": [
        {
          "name": "Science Tooth Fairy Narrative",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cavities vs. Toothpaste, book by Didi Dragon",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 120,
      "start_date": "2022-09-01",
      "completion_date": "2024-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07711301"
    },
    {
      "nct_id": "NCT02366689",
      "title": "Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Triclosan/fluoride toothpaste",
          "type": "DRUG"
        },
        {
          "name": "stannous fluoride toothpaste",
          "type": "DRUG"
        },
        {
          "name": "fluoride only toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Cetylpyridinium chloride mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Fluoride only mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 179,
      "start_date": "2014-06",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2016-03-30",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 1,
      "location_summary": "Cedar Knolls, New Jersey",
      "locations": [
        {
          "city": "Cedar Knolls",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02366689"
    },
    {
      "nct_id": "NCT00898313",
      "title": "Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lung Cancer"
      ],
      "interventions": [
        {
          "name": "comparative genomic hybridization",
          "type": "GENETIC"
        },
        {
          "name": "gene expression microarray analysis",
          "type": "GENETIC"
        },
        {
          "name": "proteomic profiling analysis",
          "type": "GENETIC"
        },
        {
          "name": "biologic sample preservation procedure",
          "type": "OTHER"
        },
        {
          "name": "nasal brushing",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood draw",
          "type": "PROCEDURE"
        },
        {
          "name": "Urine collection",
          "type": "PROCEDURE"
        },
        {
          "name": "sputum sample",
          "type": "PROCEDURE"
        },
        {
          "name": "fluorescence bronchoscopy with airway biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "fine needle aspiration of the lung",
          "type": "PROCEDURE"
        },
        {
          "name": "thoracentesis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "GENETIC",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt-Ingram Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4000,
      "start_date": "2003-12",
      "completion_date": "2027-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-27",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 2,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00898313"
    },
    {
      "nct_id": "NCT03196648",
      "title": "Randomized Trial of a Gum Health Formulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontal Diseases",
        "Gingivitis",
        "Periodontitis",
        "Halitosis"
      ],
      "interventions": [
        {
          "name": "Gingival health formulation in an accelerating device",
          "type": "OTHER"
        },
        {
          "name": "Gingival health formulation on a toothbrush",
          "type": "OTHER"
        },
        {
          "name": "OTC fluoride toothpaste",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Glo Science, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 39,
      "start_date": "2015-05-01",
      "completion_date": "2016-11-30",
      "has_results": false,
      "last_update_posted_date": "2017-06-23",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03196648"
    },
    {
      "nct_id": "NCT06151223",
      "title": "A Prospective Registry for Patients at High-Risk for Pancreatic Cancer",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pancreatic Cancer",
        "Pancreatic Ductal Adenocarcinoma",
        "PDAC",
        "PDAC - Pancreatic Ductal Adenocarcinoma"
      ],
      "interventions": [
        {
          "name": "Bio-specimen Collection: Blood",
          "type": "OTHER"
        },
        {
          "name": "Bio-specimen Collection: Pancreatic Juice",
          "type": "OTHER"
        },
        {
          "name": "MRI",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5000,
      "start_date": "2021-07-13",
      "completion_date": "2031-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06151223"
    },
    {
      "nct_id": "NCT07441148",
      "title": "Digital vs. Parent Modeled Toothbrushing",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Plaque Reduction"
      ],
      "interventions": [
        {
          "name": "MoodBrush Digital Application",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "3 Years to 6 Years"
      },
      "enrollment_count": 112,
      "start_date": "2026-01-05",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07441148"
    },
    {
      "nct_id": "NCT05612048",
      "title": "A Study of Tooth Erosion in People With Esophagogastric Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Esophagogastric Cancer"
      ],
      "interventions": [
        {
          "name": "Survey",
          "type": "OTHER"
        },
        {
          "name": "Intra-oral camera",
          "type": "OTHER"
        },
        {
          "name": "Optional Salvia sample",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 174,
      "start_date": "2022-11-03",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-09-13T02:24:22.688Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05612048"
    }
  ]
}