{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Toothpaste&page=2",
    "query": {
      "intervention": "Toothpaste",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Toothpaste&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T08:39:19.860Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07428603",
      "title": "Extrinsic Tooth Whitening Evaluation of a Whitening Toothpaste",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stain Removal Efficacy"
      ],
      "interventions": [
        {
          "name": "Whitening Test Dentifrice (Code 826)",
          "type": "OTHER"
        },
        {
          "name": "Control dentifrice (Code 378)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Church & Dwight Company, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 118,
      "start_date": "2024-08-08",
      "completion_date": "2024-09-20",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07428603"
    },
    {
      "nct_id": "NCT04915898",
      "title": "Hospital-acquired Pneumonia Prevention: Intervention, Evaluation & Research",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthcare-Associated Pneumonia"
      ],
      "interventions": [
        {
          "name": "Oral Hygiene - teeth brushing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Orlando Health, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8709,
      "start_date": "2018-10-01",
      "completion_date": "2020-04-30",
      "has_results": false,
      "last_update_posted_date": "2024-02-12",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04915898"
    },
    {
      "nct_id": "NCT06140771",
      "title": "A Clinical Study to Assess the Gingivitis Effects of Various Dentifrices",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "0.76% Sodium Monofluorophosphate Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "1.15% Sodium Monofluorophosphate Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "0.454% Stannous Fluoride Dentifrice",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 115,
      "start_date": "2021-10-20",
      "completion_date": "2022-02-06",
      "has_results": false,
      "last_update_posted_date": "2023-11-20",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 1,
      "location_summary": "Whittier, California",
      "locations": [
        {
          "city": "Whittier",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06140771"
    },
    {
      "nct_id": "NCT05756673",
      "title": "A Study of Virtually Supervised Mouthwash and Interdental Brushes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Colgate Cavity Protection Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "LISTERINE ZERO Alcohol Mouthwash COOL MINT",
          "type": "DRUG"
        },
        {
          "name": "LISTERINE COOL MINT Antiseptic Mouthwash",
          "type": "DRUG"
        },
        {
          "name": "TePe Original Interdental Brush",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 292,
      "start_date": "2023-02-09",
      "completion_date": "2023-10-03",
      "has_results": false,
      "last_update_posted_date": "2023-10-17",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05756673"
    },
    {
      "nct_id": "NCT06352645",
      "title": "Evaluation of Safety and Efficacy of Bixdo Ultra Compact Water Flosser",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Plaque Induced Gingivitis"
      ],
      "interventions": [
        {
          "name": "Bixdo Ultra Compact Water Flosser",
          "type": "DEVICE"
        },
        {
          "name": "Manual toothbrush",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 165,
      "start_date": "2025-03-04",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06352645"
    },
    {
      "nct_id": "NCT07761715",
      "title": "The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Sensitive Whitening Toothpaste, Containing 5% KNO3 (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic Stains Over 4 Weeks of Unsupervised Use.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Teeth Staining"
      ],
      "interventions": [
        {
          "name": "Toothpaste",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boka LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-05-11",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-13",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07761715"
    },
    {
      "nct_id": "NCT06140784",
      "title": "A Clinical Study to Assess the Gingivitis and Plaque Effects of Various Dentifrices",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "0.76% Sodium Monofluorophosphate Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "0.454% Stannous Fluoride Dentifrice",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 116,
      "start_date": "2023-09-02",
      "completion_date": "2023-12-10",
      "has_results": false,
      "last_update_posted_date": "2024-03-01",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 1,
      "location_summary": "Whittier, California",
      "locations": [
        {
          "city": "Whittier",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06140784"
    },
    {
      "nct_id": "NCT01014143",
      "title": "Evaluating Commercial Anti-Plaque Products and Oral Rinse",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Dental Plaque"
      ],
      "interventions": [
        {
          "name": "Fluoride",
          "type": "DRUG"
        },
        {
          "name": "Chlorhexidine digluconate",
          "type": "DRUG"
        },
        {
          "name": "Fluoride, triclosan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "23 Years",
        "maximum_age": "81 Years",
        "sex": "ALL",
        "summary": "23 Years to 81 Years"
      },
      "enrollment_count": 26,
      "start_date": "2007-08",
      "completion_date": "2007-09",
      "has_results": true,
      "last_update_posted_date": "2011-06-14",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 1,
      "location_summary": "Northfield, New Jersey",
      "locations": [
        {
          "city": "Northfield",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01014143"
    },
    {
      "nct_id": "NCT04954313",
      "title": "Baseline Oral Health Study: UnCoVer the Connections to General Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Diabetes Type 2"
      ],
      "interventions": [
        {
          "name": "Subgingival chlorhexidine irrigation",
          "type": "DRUG"
        },
        {
          "name": "Dental Supplies",
          "type": "OTHER"
        },
        {
          "name": "Periodonal Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 786,
      "start_date": "2021-09-28",
      "completion_date": "2025-02-01",
      "has_results": true,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Kannapolis, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Kannapolis",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04954313"
    },
    {
      "nct_id": "NCT01691560",
      "title": "Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Dentine Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "5% calcium sodium phosphosilicate/ sodium monofluorophosphate dentifrice",
          "type": "DRUG"
        },
        {
          "name": "0% calcium sodium phosphosilicate/sodium monofluorophosphate dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Sodium monofluorophosphate dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Sodium fluoride dentifrice",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 140,
      "start_date": "2012-08",
      "completion_date": "2012-11",
      "has_results": true,
      "last_update_posted_date": "2014-05-29",
      "last_synced_at": "2026-09-04T08:39:19.860Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01691560"
    }
  ]
}