{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical",
    "query": {
      "intervention": "Topical"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 2624,
    "total_pages": 263,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T08:15:25.061Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05501860",
      "title": "A Safety Study of of AG-920 Sterile Topical Ophthalmic Solution",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia, Local"
      ],
      "interventions": [
        {
          "name": "AG-920",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "American Genomics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 249,
      "start_date": "2022-07-30",
      "completion_date": "2022-12-07",
      "has_results": true,
      "last_update_posted_date": "2024-10-09",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 2,
      "location_summary": "Newport Beach, California • McAllen, Texas",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "McAllen",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05501860"
    },
    {
      "nct_id": "NCT00934089",
      "title": "A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Glaucoma, Open-Angle",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "PF-04217329",
          "type": "DRUG"
        },
        {
          "name": "latanoprost vehicle",
          "type": "DRUG"
        },
        {
          "name": "latanoprost",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 31,
      "start_date": "2010-01",
      "completion_date": "2010-06",
      "has_results": true,
      "last_update_posted_date": "2021-05-03",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 8,
      "location_summary": "Cypress, California • Garden Grove, California • Gardena, California + 4 more",
      "locations": [
        {
          "city": "Cypress",
          "state": "California"
        },
        {
          "city": "Garden Grove",
          "state": "California"
        },
        {
          "city": "Gardena",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00934089"
    },
    {
      "nct_id": "NCT05336825",
      "title": "CO2 Laser vs Lidocaine for Vestibulodynia in Premenopausal Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vulvodynia"
      ],
      "interventions": [
        {
          "name": "CO2 laser",
          "type": "DEVICE"
        },
        {
          "name": "Lidocaine patch 5%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Atlantic Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2019-04-01",
      "completion_date": "2021-01-31",
      "has_results": false,
      "last_update_posted_date": "2022-04-20",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 1,
      "location_summary": "Denville, New Jersey",
      "locations": [
        {
          "city": "Denville",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05336825"
    },
    {
      "nct_id": "NCT01533376",
      "title": "Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Sturge Weber Syndrome",
        "Port-wine Mark"
      ],
      "interventions": [
        {
          "name": "Timolol",
          "type": "DRUG"
        },
        {
          "name": "Preservative free artificial tear gel.",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wills Eye",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "2 Years to 10 Years"
      },
      "enrollment_count": 3,
      "start_date": "2012-02",
      "completion_date": "2019-02",
      "has_results": false,
      "last_update_posted_date": "2019-03-21",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01533376"
    },
    {
      "nct_id": "NCT05849090",
      "title": "Vancomycin and Tobramycin Powder Use in Acute Open Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Infections"
      ],
      "interventions": [
        {
          "name": "Cephalosporin or clindamycin/vancomycin antibiotics..",
          "type": "DRUG"
        },
        {
          "name": "Vancomycin and Tobramycin antibiotics.",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 10,
      "start_date": "2023-03-27",
      "completion_date": "2024-12-12",
      "has_results": false,
      "last_update_posted_date": "2024-12-20",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05849090"
    },
    {
      "nct_id": "NCT04169490",
      "title": "\"A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities\"",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Scar",
        "Keloid",
        "Hypertrophic Scar",
        "Cicatrix"
      ],
      "interventions": [
        {
          "name": "Placebo Cream Base Emulsion Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "FS2 Emulsion Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "Active Comparator Onion Skin Extract Gel (Mederma)",
          "type": "OTHER"
        },
        {
          "name": "Active Comparator Silicone Gel (Kelo-Cote)",
          "type": "OTHER"
        },
        {
          "name": "Active Comparator Silicone Gel (Kelo-Cote) + FS2 Emulsion Moisturizer",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Center for Clinical and Cosmetic Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2019-02-07",
      "completion_date": "2020-11-03",
      "has_results": false,
      "last_update_posted_date": "2022-03-21",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 1,
      "location_summary": "Aventura, Florida",
      "locations": [
        {
          "city": "Aventura",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04169490"
    },
    {
      "nct_id": "NCT01988779",
      "title": "Oral Versus Topical Antibiotics for Chronic Rhinosinusitis Exacerbations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Rhinosinusitis"
      ],
      "interventions": [
        {
          "name": "oral levofloxacin",
          "type": "DRUG"
        },
        {
          "name": "nebulized levofloxacin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2013-10",
      "completion_date": "2020-12-31",
      "has_results": true,
      "last_update_posted_date": "2021-03-24",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01988779"
    },
    {
      "nct_id": "NCT01277640",
      "title": "Male Tolerance Study of Dapivirine Gel Following Multiple Topical Penile Exposures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Topical Penile Exposures"
      ],
      "interventions": [
        {
          "name": "dapivirine",
          "type": "DRUG"
        },
        {
          "name": "matched placebo",
          "type": "DRUG"
        },
        {
          "name": "universal placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "International Partnership for Microbicides, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 48,
      "start_date": "2011-03",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2017-09-08",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01277640"
    },
    {
      "nct_id": "NCT04725110",
      "title": "Direct Topical Lung T3 Treatment to Improve Outcome & Sequelae of COVID-19 Acute Respiratory Distress Syndrome",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Covid19",
        "SARS-CoV Infection",
        "ARDS",
        "ARDS, Human"
      ],
      "interventions": [
        {
          "name": "Instilled T3",
          "type": "DRUG"
        },
        {
          "name": "Placebo Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2026-01-15",
      "completion_date": "2031-10-15",
      "has_results": false,
      "last_update_posted_date": "2026-02-10",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04725110"
    },
    {
      "nct_id": "NCT05278013",
      "title": "Utility of 2- Octyl Cyanoacrylate (2-OCA)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ascites",
        "Fluid Loss"
      ],
      "interventions": [
        {
          "name": "Dermabond",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Methodist Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 134,
      "start_date": "2022-01-13",
      "completion_date": "2024-01-13",
      "has_results": false,
      "last_update_posted_date": "2023-07-10",
      "last_synced_at": "2026-09-03T08:15:25.061Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05278013"
    }
  ]
}