{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical+Chlorhexidine%2C+4%25",
    "query": {
      "intervention": "Topical Chlorhexidine, 4%"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical+Chlorhexidine%2C+4%25&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T15:01:57.679Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05797818",
      "title": "Red Light Photobiomodulation and Topical Disinfectants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Healthcare Associated Infection",
        "Nosocomial Infection",
        "Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "Methylene Blue Only",
          "type": "DEVICE"
        },
        {
          "name": "Chlorhexidine Gluconate Only",
          "type": "DEVICE"
        },
        {
          "name": "Methylene Blue + Chlorhexidine Gluconate",
          "type": "DEVICE"
        },
        {
          "name": "Light Only",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ondine Biomedical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2023-01-10",
      "completion_date": "2023-02-08",
      "has_results": false,
      "last_update_posted_date": "2023-04-04",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 1,
      "location_summary": "Bothell, Washington",
      "locations": [
        {
          "city": "Bothell",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05797818"
    },
    {
      "nct_id": "NCT07142408",
      "title": "The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Surgical Wound Infection"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine gluconate (4%)",
          "type": "DRUG"
        },
        {
          "name": "Mupirocin 2% Ointment",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Cooper Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 848,
      "start_date": "2023-03-13",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2025-08-26",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 1,
      "location_summary": "Marlton, New Jersey",
      "locations": [
        {
          "city": "Marlton",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07142408"
    },
    {
      "nct_id": "NCT06397781",
      "title": "Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Atopic Dermatitis"
      ],
      "interventions": [
        {
          "name": "Skin Cleanser Combination No.1",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2031-01-01",
      "completion_date": "2039-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06397781"
    },
    {
      "nct_id": "NCT04218799",
      "title": "Human Microbiome and Healthcare Associated Infections - Nursing Home Dwelling Older Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Human Microbiome"
      ],
      "interventions": [
        {
          "name": "Intranasal Mupirocin and Topical Chlorhexidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2014-08-12",
      "completion_date": "2015-09-22",
      "has_results": true,
      "last_update_posted_date": "2023-06-06",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland • Perry Point, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Perry Point",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04218799"
    },
    {
      "nct_id": "NCT01349192",
      "title": "Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cystic Fibrosis",
        "Methicillin-resistant Staphylococcus Aureus"
      ],
      "interventions": [
        {
          "name": "Rifampin",
          "type": "DRUG"
        },
        {
          "name": "Trimethoprim/Sulfamethoxazole",
          "type": "DRUG"
        },
        {
          "name": "Minocycline",
          "type": "DRUG"
        },
        {
          "name": "Mupirocin",
          "type": "DRUG"
        },
        {
          "name": "chlorhexidine gluconate oral rinse",
          "type": "DRUG"
        },
        {
          "name": "2% Chlorhexidine solution wipes",
          "type": "DRUG"
        },
        {
          "name": "Environmental Decontamination",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "4 Years to 45 Years"
      },
      "enrollment_count": 47,
      "start_date": "2011-04",
      "completion_date": "2015-05",
      "has_results": true,
      "last_update_posted_date": "2017-05-15",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 13,
      "location_summary": "Birmingham, Alabama • Aurora, Colorado • Gainesville, Florida + 9 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01349192"
    },
    {
      "nct_id": "NCT05586776",
      "title": "Decolonization to Reduce After-Surgery Events of Surgical Site Infection",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "4% Chlorhexidine Gluconate",
          "type": "DRUG"
        },
        {
          "name": "2% Mupirocin",
          "type": "DRUG"
        },
        {
          "name": "Soap Without Antiseptic Properties (Placebo)",
          "type": "DRUG"
        },
        {
          "name": "Placebo Nasal Ointment",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2700,
      "start_date": "2023-01-17",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-21",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 4,
      "location_summary": "Newport Beach, California • Orange, California • Sacramento, California + 1 more",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05586776"
    },
    {
      "nct_id": "NCT05090657",
      "title": "Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Surgical Site Infections",
        "Nosocomial Infection",
        "Healthcare Associated Infections"
      ],
      "interventions": [
        {
          "name": "methylene blue 0.01%/chlorhexidine gluconate 0.25% + light activation",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Ondine Biomedical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 322,
      "start_date": "2022-02-04",
      "completion_date": "2022-08-06",
      "has_results": false,
      "last_update_posted_date": "2022-08-22",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 1,
      "location_summary": "Savannah, Georgia",
      "locations": [
        {
          "city": "Savannah",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05090657"
    },
    {
      "nct_id": "NCT03118232",
      "title": "Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hospitalization",
        "Infection"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine gluconate (CHG)",
          "type": "DRUG"
        },
        {
          "name": "Iodophor (10% povidone-iodine)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13952,
      "start_date": "2017-04-03",
      "completion_date": "2023-10-10",
      "has_results": true,
      "last_update_posted_date": "2023-12-27",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 28,
      "location_summary": "Anaheim, California • Bellflower, California • Capistrano Beach, California + 9 more",
      "locations": [
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Anaheim",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03118232"
    },
    {
      "nct_id": "NCT04222699",
      "title": "Cultures Before and After Decolonization in Community Dwelling Adults With Current S. Aureus Colonization",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Human Microbiome"
      ],
      "interventions": [
        {
          "name": "Mupirocin calcium ointment, 2%",
          "type": "DRUG"
        },
        {
          "name": "Topical Chlorhexidine, 4%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 58,
      "start_date": "2012-09-18",
      "completion_date": "2014-11-18",
      "has_results": true,
      "last_update_posted_date": "2020-04-14",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04222699"
    },
    {
      "nct_id": "NCT00560599",
      "title": "A Randomized Clinical Trial to Prevent Recurrent CA-MRSA Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Methicillin Resistant Staphylococcus Aureus Skin Infections"
      ],
      "interventions": [
        {
          "name": "mupirocin and chlorhexidine",
          "type": "DRUG"
        },
        {
          "name": "household cleaning and disinfection",
          "type": "BEHAVIORAL"
        },
        {
          "name": "mupirocin, chlorhexidine, & household cleaning/disinfection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "loren g miller",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Month and older"
      },
      "enrollment_count": 350,
      "start_date": "2007-04",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2025-03-10",
      "last_synced_at": "2026-09-24T15:01:57.679Z",
      "location_count": 6,
      "location_summary": "Anaheim, California • Bellflower, California • Harbor City, California + 3 more",
      "locations": [
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Bellflower",
          "state": "California"
        },
        {
          "city": "Harbor City",
          "state": "California"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Panorama City",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00560599"
    }
  ]
}