{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical+Nitroglycerine", "query": { "intervention": "Topical Nitroglycerine" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 21, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical+Nitroglycerine&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-06T16:44:23.527Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00378521", "title": "Dose Response Study of a Topical Gel for the Treatment of Raynaud's Phenomenon", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Raynaud's Disease", "Raynaud's Disease Secondary to Scleroderma", "Raynaud's Disease Secondary to Autoimmune Disease" ], "interventions": [ { "name": "MQX-503", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MediQuest Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 15, "start_date": "2006-07", "completion_date": "2006-07", "has_results": false, "last_update_posted_date": "2007-05-30", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 1, "location_summary": "Renton, Washington", "locations": [ { "city": "Renton", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00378521" }, { "nct_id": "NCT00686231", "title": "Radial Artery Dilation Study: The Effect of Topical Administration of Nitroglycerin and Lidocaine Versus Lidocaine Alone of the Radial Artery Diameter", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Nitroglycerin 15mg", "type": "DRUG" }, { "name": "Nitroglycerin 30mg", "type": "DRUG" }, { "name": "Lidocaine 20mg", "type": "DRUG" }, { "name": "Lidocaine 40mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "18 Years to 35 Years" }, "enrollment_count": 19, "start_date": "2008-05", "completion_date": "2008-12", "has_results": true, "last_update_posted_date": "2020-03-06", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00686231" }, { "nct_id": "NCT00513994", "title": "MQX-503 vs Nitroglycerin Ointment: A Pharmacokinetic Comparison in Normal Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Nitroglycerin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MediQuest Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 6, "start_date": "2007-08", "completion_date": "2007-10", "has_results": false, "last_update_posted_date": "2008-04-11", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 1, "location_summary": "Tacoma, Washington", "locations": [ { "city": "Tacoma", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00513994" }, { "nct_id": "NCT00641953", "title": "IMX-150 Cream for Diabetic Neuropathy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetic Peripheral Neuropathy" ], "interventions": [ { "name": "IMX-150", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Procris Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 155, "start_date": "2007-08", "completion_date": "2008-03", "has_results": false, "last_update_posted_date": "2008-06-17", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 7, "location_summary": "Brooksville, Florida • Jupiter, Florida • Miami, Florida + 4 more", "locations": [ { "city": "Brooksville", "state": "Florida" }, { "city": "Jupiter", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Ormond Beach", "state": "Florida" }, { "city": "Oviedo", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00641953" }, { "nct_id": "NCT03259165", "title": "Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Heart Failure", "Heart Failure Acute", "Acute Cardiac Failure", "Acute Cardiac Pulmonary Edema" ], "interventions": [ { "name": "Nitrates", "type": "DRUG" }, { "name": "Loop Diuretics", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 52, "start_date": "2017-12-14", "completion_date": "2021-12-31", "has_results": true, "last_update_posted_date": "2024-08-20", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 3, "location_summary": "Indianapolis, Indiana • Nashville, Tennessee", "locations": [ { "city": "Indianapolis", "state": "Indiana" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03259165" }, { "nct_id": "NCT00577304", "title": "A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenon", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Raynaud's Disease", "Raynaud's Disease Secondary to Scleroderma", "Raynaud's Disease Secondary to Other Autoimmune Disease" ], "interventions": [ { "name": "Nitroglycerin", "type": "DRUG" }, { "name": "Topical AmphiMatrix", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MediQuest Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "15 Years to 70 Years" }, "enrollment_count": 200, "start_date": "2007-12", "completion_date": "2008-03", "has_results": false, "last_update_posted_date": "2010-02-05", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 17, "location_summary": "Stanford, California • Denver, Colorado • Farmington, Connecticut + 14 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Farmington", "state": "Connecticut" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00577304" }, { "nct_id": "NCT01155167", "title": "Topical Radial Artery Vasodilation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Cardiac Catheterization", "Spasm" ], "interventions": [ { "name": "Nitroglycerin and lidocaine", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 86, "start_date": "2010-07", "completion_date": "2012-08", "has_results": true, "last_update_posted_date": "2018-09-25", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01155167" }, { "nct_id": "NCT00253331", "title": "Lab Study of MQX-503 in Treatment of Raynaud's", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Raynaud Disease", "Raynaud Disease Secondary to Scleroderma", "Raynaud Secondary to Other Autoimmune Disease" ], "interventions": [ { "name": "topical organogel with nitroglycerin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MediQuest Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 36, "start_date": "2004-11", "completion_date": "2005-09", "has_results": false, "last_update_posted_date": "2007-05-30", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 2, "location_summary": "Baltimore, Maryland • Seattle, Washington", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00253331" }, { "nct_id": "NCT00266669", "title": "Phase III Study of Topical Gel for Treatment and Prevention of Raynaud's Phenomenon", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Raynaud's Disease" ], "interventions": [ { "name": "Topical organogel with nitroglycerin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MediQuest Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 200, "start_date": "2005-12", "completion_date": "2006-05", "has_results": false, "last_update_posted_date": "2007-08-08", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 17, "location_summary": "Stanford, California • Denver, Colorado • Farmington, Connecticut + 14 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Farmington", "state": "Connecticut" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00266669" }, { "nct_id": "NCT00259701", "title": "Microvascular Reactivity.", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Diabetes", "Retinopathy", "Vascular Pathology" ], "interventions": [ { "name": "Laser Doppler Flowmetry with topical acetylcholine and nitroglycerin", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2005-06", "completion_date": "2005-09", "has_results": false, "last_update_posted_date": "2006-10-06", "last_synced_at": "2026-09-06T16:44:23.527Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00259701" } ] }