{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical+Vehicle+solution&page=2",
    "query": {
      "intervention": "Topical Vehicle solution",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical+Vehicle+solution&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-15T14:27:36.283Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03925727",
      "title": "Tavilermide Ophthalmic Solution for the Treatment of Dry Eye",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Keratoconjunctivitis Sicca",
        "Dry Eye"
      ],
      "interventions": [
        {
          "name": "Tavilermide ophthalmic solution",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Mimetogen Pharmaceuticals USA, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 623,
      "start_date": "2019-03-28",
      "completion_date": "2020-06-11",
      "has_results": true,
      "last_update_posted_date": "2023-04-05",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 22,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Newport Beach, California + 19 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "Littleton",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03925727"
    },
    {
      "nct_id": "NCT03960866",
      "title": "Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Open Angle Glaucoma",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Phentolamine Mesylate Ophthalmic Solution 1%",
          "type": "DRUG"
        },
        {
          "name": "Phentolamine Mesylate Ophthalmic Solution Vehicle (Placebo)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Ocuphire Pharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2019-05-28",
      "completion_date": "2019-09-11",
      "has_results": true,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 5,
      "location_summary": "Mission Hills, California • Morrow, Georgia • Ann Arbor, Michigan + 2 more",
      "locations": [
        {
          "city": "Mission Hills",
          "state": "California"
        },
        {
          "city": "Morrow",
          "state": "Georgia"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03960866"
    },
    {
      "nct_id": "NCT03210337",
      "title": "A Phase2 of A-101 Topical Solution in Subjects With Common Warts",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Common Wart"
      ],
      "interventions": [
        {
          "name": "A-101 Topical Solution",
          "type": "DRUG"
        },
        {
          "name": "A-101 Vehicle Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Aclaris Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 157,
      "start_date": "2017-08-01",
      "completion_date": "2018-03-16",
      "has_results": true,
      "last_update_posted_date": "2019-05-01",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 17,
      "location_summary": "Scottsdale, Arizona • Rogers, Arkansas • San Diego, California + 13 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Rogers",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03210337"
    },
    {
      "nct_id": "NCT02160626",
      "title": "Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Seborrheic Keratosis"
      ],
      "interventions": [
        {
          "name": "A-101 Vehicle",
          "type": "DRUG"
        },
        {
          "name": "A-101 (40) Topical Solution",
          "type": "DRUG"
        },
        {
          "name": "A-101 (32.5) Topical Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Aclaris Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 172,
      "start_date": "2014-06",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2019-01-03",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 5,
      "location_summary": "Snellville, Georgia • Clinton Township, Michigan • Portland, Oregon + 2 more",
      "locations": [
        {
          "city": "Snellville",
          "state": "Georgia"
        },
        {
          "city": "Clinton Township",
          "state": "Michigan"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Lynchburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02160626"
    },
    {
      "nct_id": "NCT05285644",
      "title": "Study Evaluating the Safety and Efficacy of AR-15512",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dry Eye Disease"
      ],
      "interventions": [
        {
          "name": "0.003% AR-15512 ophthalmic solution",
          "type": "DRUG"
        },
        {
          "name": "AR-15512 vehicle ophthalmic solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Aerie Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 465,
      "start_date": "2022-05-09",
      "completion_date": "2023-07-24",
      "has_results": true,
      "last_update_posted_date": "2025-07-23",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 23,
      "location_summary": "Glendale, California • Torrance, California • Colorado Springs, Colorado + 19 more",
      "locations": [
        {
          "city": "Glendale",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Waterbury",
          "state": "Connecticut"
        },
        {
          "city": "Delray Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05285644"
    },
    {
      "nct_id": "NCT02597777",
      "title": "Topical Acetyl Hexapeptide-8 and the Cosmetic Appearance of Oily Skin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oily Skin"
      ],
      "interventions": [
        {
          "name": "Acetyl Hexapeptide-8",
          "type": "OTHER"
        },
        {
          "name": "Placebo vehicle",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2016-01",
      "completion_date": "2016-02",
      "has_results": false,
      "last_update_posted_date": "2017-04-05",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02597777"
    },
    {
      "nct_id": "NCT03292809",
      "title": "CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Dry Eye Disease"
      ],
      "interventions": [
        {
          "name": "CyclASol topical ocular, eye drops",
          "type": "DRUG"
        },
        {
          "name": "Vehicle topical ocular, eye drops",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novaliq GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 328,
      "start_date": "2017-10-19",
      "completion_date": "2018-06-20",
      "has_results": true,
      "last_update_posted_date": "2022-12-22",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 9,
      "location_summary": "Newport Beach, California • Torrance, California • Indianapolis, Indiana + 6 more",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Andover",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03292809"
    },
    {
      "nct_id": "NCT01841996",
      "title": "Pharmacokinetics and Safety Study of ME1111 in Moderate to Severe Onychomycosis Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Onychomycosis"
      ],
      "interventions": [
        {
          "name": "ME1111 solution",
          "type": "DRUG"
        },
        {
          "name": "Vehicle Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Meiji Seika Pharma Co., Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2013-03",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2013-12-17",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 2,
      "location_summary": "Austin, Texas • College Station, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "College Station",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01841996"
    },
    {
      "nct_id": "NCT03615196",
      "title": "Study of the Safety of USB005 in Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "USB005 (aclerastide) Ophthalmic Solution",
          "type": "DRUG"
        },
        {
          "name": "USB005 Ophthalmic Solution Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "US Biotest, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 32,
      "start_date": "2018-07-25",
      "completion_date": "2019-04-02",
      "has_results": false,
      "last_update_posted_date": "2019-04-04",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 1,
      "location_summary": "Cypress, California",
      "locations": [
        {
          "city": "Cypress",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03615196"
    },
    {
      "nct_id": "NCT04097730",
      "title": "Steroids and Cross-linking for Ulcer Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Keratitis Bacterial"
      ],
      "interventions": [
        {
          "name": "Moxifloxacin Ophthalmic",
          "type": "DRUG"
        },
        {
          "name": "Difluprednate Ophthalmic",
          "type": "DRUG"
        },
        {
          "name": "Riboflavin Ophthalmic",
          "type": "DRUG"
        },
        {
          "name": "Topical Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Thomas M. Lietman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 280,
      "start_date": "2020-09-24",
      "completion_date": "2024-09-18",
      "has_results": false,
      "last_update_posted_date": "2025-02-03",
      "last_synced_at": "2026-09-15T14:27:36.283Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Miami, Florida",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04097730"
    }
  ]
}