{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical+anesthetic+gel",
    "query": {
      "intervention": "Topical anesthetic gel"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topical+anesthetic+gel&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T04:08:23.064Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04766996",
      "title": "PROUD Study - Preventing Opioid Use Disorders",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anesthesia",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "Guided mindfulness exercises",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-administered aromatherapy",
          "type": "OTHER"
        },
        {
          "name": "Baby aspirin",
          "type": "DRUG"
        },
        {
          "name": "Tylenol/Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Pregabalin",
          "type": "DRUG"
        },
        {
          "name": "Prednisone",
          "type": "DRUG"
        },
        {
          "name": "Meloxicam",
          "type": "DRUG"
        },
        {
          "name": "Prilosec",
          "type": "DRUG"
        },
        {
          "name": "Tramadol",
          "type": "DRUG"
        },
        {
          "name": "Voltaren",
          "type": "DRUG"
        },
        {
          "name": "Zofran",
          "type": "DRUG"
        },
        {
          "name": "Pepcid",
          "type": "DRUG"
        },
        {
          "name": "Reglan",
          "type": "DRUG"
        },
        {
          "name": "Versed",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Propofol",
          "type": "DRUG"
        },
        {
          "name": "Ancef",
          "type": "DRUG"
        },
        {
          "name": "Tranexamic Acid (TXA)",
          "type": "DRUG"
        },
        {
          "name": "Decadron",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Toradol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 57,
      "start_date": "2021-05-17",
      "completion_date": "2021-12-27",
      "has_results": true,
      "last_update_posted_date": "2023-06-22",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04766996"
    },
    {
      "nct_id": "NCT04536493",
      "title": "Comparison of 2 Application Techniques for LET Gel Used Prior to Simple Laceration Repair",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "LET",
        "Laceration of Skin"
      ],
      "interventions": [
        {
          "name": "LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (1 application)",
          "type": "DRUG"
        },
        {
          "name": "LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (3 applications)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital of Orange County",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "7 Years to 18 Years"
      },
      "enrollment_count": 48,
      "start_date": "2019-06-19",
      "completion_date": "2020-06-25",
      "has_results": false,
      "last_update_posted_date": "2020-09-02",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04536493"
    },
    {
      "nct_id": "NCT05934253",
      "title": "The Effects of Low Viscosity Chloroprocaine Ophthalmic Gel 3% on the Bactericidal Action of Povidone-Iodine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Antiseptic",
        "Anesthesia, Local"
      ],
      "interventions": [
        {
          "name": "Chloroprocaine ophthalmic gel 3%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Harrow Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 100,
      "start_date": "2023-07-15",
      "completion_date": "2024-02-15",
      "has_results": false,
      "last_update_posted_date": "2025-09-16",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 1,
      "location_summary": "Brandon, Florida",
      "locations": [
        {
          "city": "Brandon",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05934253"
    },
    {
      "nct_id": "NCT04203225",
      "title": "Comparison of Two Application Techniques for LET Gel",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Lacerations",
        "Pain, Procedural",
        "LET"
      ],
      "interventions": [
        {
          "name": "LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 48,
      "start_date": "2017-05-22",
      "completion_date": "2019-11-12",
      "has_results": true,
      "last_update_posted_date": "2021-02-18",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 2,
      "location_summary": "Orange, California • Torrance, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04203225"
    },
    {
      "nct_id": "NCT01027611",
      "title": "Patient Assessment of Topical Anesthetic Effectiveness for Intravitreal Injections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "proparacaine HCL 0.5%",
          "type": "DRUG"
        },
        {
          "name": "proparacaine HCL 0.5% + 4% lidocaine solution",
          "type": "DRUG"
        },
        {
          "name": "3.5% viscous lidocaine gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Illinois Retina Associates",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2009-10",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2010-05-04",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 1,
      "location_summary": "Joliet, Illinois",
      "locations": [
        {
          "city": "Joliet",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01027611"
    },
    {
      "nct_id": "NCT03779659",
      "title": "Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Fear",
        "Anesthesia, Local",
        "Pediatric Dentistry"
      ],
      "interventions": [
        {
          "name": "Synapse TENS device",
          "type": "DEVICE"
        },
        {
          "name": "Topical anesthetic gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "6 Years to 14 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-07",
      "completion_date": "2023-02",
      "has_results": false,
      "last_update_posted_date": "2021-06-08",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03779659"
    },
    {
      "nct_id": "NCT02423434",
      "title": "Evaluation of Corneal Confocal Microscopy for the Identification and Prediction of Neuropathy in Type 1 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Polyneuropathy",
        "Diabetes Mellitus",
        "Diabetes Mellitus, Type 1",
        "Diabetes Mellitus, Type 2",
        "Diabetes Complications"
      ],
      "interventions": [
        {
          "name": "Exposure: Corneal nerve fibre morphology by the CCM Procedure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Samuel Lunenfeld Research Institute, Mount Sinai Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 624,
      "start_date": "2014-09",
      "completion_date": "2018-08",
      "has_results": false,
      "last_update_posted_date": "2019-11-06",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02423434"
    },
    {
      "nct_id": "NCT06043063",
      "title": "Local Anesthesia Before Bulkamid Injection",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Urinary Incontinence",
        "Intrinsic Sphincter Deficiency"
      ],
      "interventions": [
        {
          "name": "Topical lidocaine",
          "type": "PROCEDURE"
        },
        {
          "name": "EMLA cream",
          "type": "PROCEDURE"
        },
        {
          "name": "Periurethral block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Medstar Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 23,
      "start_date": "2023-09-01",
      "completion_date": "2024-12-23",
      "has_results": false,
      "last_update_posted_date": "2025-05-16",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 3,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06043063"
    },
    {
      "nct_id": "NCT04029545",
      "title": "A Multicenter, Double-blind, Randomized, Controlled, Roll-over Retreatment Study of the Safety and Pain Associated With Injections of PN40082, RV001 With Topical Anesthetic or RV001 for Lip Augmentation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lip Augmentation"
      ],
      "interventions": [
        {
          "name": "PN40082",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Prollenium Medical Technologies Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2019-06-14",
      "completion_date": "2019-12-09",
      "has_results": true,
      "last_update_posted_date": "2021-08-20",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 5,
      "location_summary": "Encinitas, California • Miami, Florida • Omaha, Nebraska + 2 more",
      "locations": [
        {
          "city": "Encinitas",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04029545"
    },
    {
      "nct_id": "NCT01951820",
      "title": "Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anesthesia of Mucous Membrane"
      ],
      "interventions": [
        {
          "name": "Pliaglis",
          "type": "DRUG"
        },
        {
          "name": "Benzocaine",
          "type": "DRUG"
        },
        {
          "name": "Articaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2013-08",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2016-07-22",
      "last_synced_at": "2026-09-29T04:08:23.064Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01951820"
    }
  ]
}