{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Topiramate+100mg", "query": { "intervention": "Topiramate 100mg" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-19T13:05:17.285Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01950520", "title": "Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Propranolol", "type": "DRUG" }, { "name": "Pindolol", "type": "DRUG" }, { "name": "Dantrolene", "type": "DRUG" }, { "name": "Magnesium Sulfate", "type": "DRUG" }, { "name": "Caffeine", "type": "DRUG" }, { "name": "Qsymia", "type": "DRUG" }, { "name": "Topiramate", "type": "DRUG" }, { "name": "Phentermine", "type": "BEHAVIORAL" }, { "name": "Naltrexone", "type": "DRUG" }, { "name": "Mirabegron 50mg", "type": "DRUG" }, { "name": "Mirabegron 200mg", "type": "DRUG" }, { "name": "Placebo Cohort 1", "type": "DRUG" }, { "name": "Placebo Cohort 2", "type": "DRUG" }, { "name": "Placebo for Mirabegron", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "MALE", "summary": "18 Years to 35 Years · Male only" }, "enrollment_count": 47, "start_date": "2014-02-07", "completion_date": "2024-06-11", "has_results": true, "last_update_posted_date": "2024-10-16", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01950520" }, { "nct_id": "NCT00802412", "title": "Topiramate to Aid Smoking Cessation in Alcohol Dependent Men", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nicotine Dependence", "Alcohol Dependence" ], "interventions": [ { "name": "Topiramate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "MALE", "summary": "18 Years to 70 Years · Male only" }, "enrollment_count": 132, "start_date": "2009-01", "completion_date": "2015-06", "has_results": true, "last_update_posted_date": "2017-01-31", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00802412" }, { "nct_id": "NCT00732108", "title": "Is Topiramate Effective in Treating Dizziness in Patient's With Migraine-Associated Dizziness", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Migraine", "Headache", "Dizziness" ], "interventions": [ { "name": "topiramate", "type": "DRUG" }, { "name": "lactulose placebo pill", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2008-11", "completion_date": null, "has_results": false, "last_update_posted_date": "2015-03-06", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00732108" }, { "nct_id": "NCT00486291", "title": "Study of VI-0521 Compared to Placebo in the Glycemic Management of Obese Diabetics", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "VI-0521", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VIVUS LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 210, "start_date": "2007-06", "completion_date": "2008-04", "has_results": true, "last_update_posted_date": "2012-09-10", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 9, "location_summary": "Birmingham, Alabama • Los Angeles, California • San Francisco, California + 6 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Spring Valley", "state": "California" }, { "city": "Walnut Creek", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00486291" }, { "nct_id": "NCT03335163", "title": "The Effect of Topiramate on Etonogestrel Concentrations in Contraceptive Implant Users", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Migraine", "Migraine;Menstrual", "Contraception" ], "interventions": [ { "name": "Topiramate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "18 Years to 45 Years · Female only" }, "enrollment_count": 48, "start_date": "2018-03-15", "completion_date": "2021-04-22", "has_results": true, "last_update_posted_date": "2022-07-13", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03335163" }, { "nct_id": "NCT04095104", "title": "Adjunct Phentermine + Topiramate After Bariatric Surgery in 12-24 Year Olds", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Obesity, Morbid", "Bariatric Surgery", "Adolescent", "Young Adult", "Drug Therapy" ], "interventions": [ { "name": "Phentermine", "type": "DRUG" }, { "name": "Immediate Release Topiramate", "type": "DRUG" }, { "name": "Placebo for Phentermine", "type": "DRUG" }, { "name": "Placebo for Immediate Release Topiramate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "24 Years", "sex": "ALL", "summary": "12 Years to 24 Years" }, "enrollment_count": 13, "start_date": "2020-01-15", "completion_date": "2022-01-25", "has_results": true, "last_update_posted_date": "2025-05-23", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04095104" }, { "nct_id": "NCT00884884", "title": "Aripiprazole and Topiramate on Free-Choice Alcohol Use", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Alcohol Dependence" ], "interventions": [ { "name": "Double Placebo", "type": "DRUG" }, { "name": "Aripiprazole 15, placebo", "type": "DRUG" }, { "name": "Aripiprazole 7.5, Placebo", "type": "DRUG" }, { "name": "Topiramate 100, Placebo", "type": "DRUG" }, { "name": "Topiramate 200, Placebo", "type": "DRUG" }, { "name": "Topiramate 100, Aripiprazole 15", "type": "DRUG" }, { "name": "Topiramate 100, Aripiprazole 7.5", "type": "DRUG" }, { "name": "Topiramate 100, Aripiprazole 15mg", "type": "DRUG" }, { "name": "Topiramate 200, Aripiprazole 7.5mg", "type": "DRUG" }, { "name": "Topiramate 200, Aripiprazole 15", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute on Alcohol Abuse and Alcoholism (NIAAA)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 90, "start_date": "2007-09", "completion_date": "2015-10", "has_results": false, "last_update_posted_date": "2015-10-07", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 1, "location_summary": "Providence, Rhode Island", "locations": [ { "city": "Providence", "state": "Rhode Island" } ], "official_url": "https://clinicaltrials.gov/study/NCT00884884" }, { "nct_id": "NCT01889602", "title": "Characterizing and Predicting Drug Effects on Cognition", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cognitive Deficits" ], "interventions": [ { "name": "Lorazepam", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Topiramate 100mg", "type": "DRUG" }, { "name": "Topiramate 150mg", "type": "DRUG" }, { "name": "Topiramate 200mg", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 60, "start_date": "2013-07", "completion_date": "2016-08", "has_results": true, "last_update_posted_date": "2019-12-17", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT01889602" }, { "nct_id": "NCT00329407", "title": "The Effects of Topiramate on Alcohol Use in Alcohol Dependent Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Alcoholism" ], "interventions": [ { "name": "Topiramate (Topamax)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boston University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 10, "start_date": "2003-09", "completion_date": "2008-06", "has_results": true, "last_update_posted_date": "2010-09-08", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00329407" }, { "nct_id": "NCT03667846", "title": "Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Post Traumatic Stress Disorder", "Alcohol Use Disorder" ], "interventions": [ { "name": "Topiramate", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 150, "start_date": "2019-10-10", "completion_date": "2025-08-31", "has_results": false, "last_update_posted_date": "2025-04-01", "last_synced_at": "2026-09-19T13:05:17.285Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03667846" } ] }