{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Total+knee+or+Hip+Arthroplasty&page=3", "query": { "intervention": "Total knee or Hip Arthroplasty", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 52, "total_pages": 6, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Total+knee+or+Hip+Arthroplasty&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Total+knee+or+Hip+Arthroplasty&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-13T13:09:19.240Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00818493", "title": "Pilot Study of the Efficacy and Safety of Q8003 in Patients Who Have Undergone Total Knee Arthroplasty or Total Hip Arthroplasty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "Q8003 (morphine sulfate and oxycodone hydrochloride)", "type": "DRUG" }, { "name": "Low dose Q8003 (morphine sulfate and oxycodone hydrochloride)", "type": "DRUG" }, { "name": "Percocet (oxycodone and acetaminophen)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "QRxPharma Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 44, "start_date": "2009-02", "completion_date": "2009-07", "has_results": false, "last_update_posted_date": "2012-05-17", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 4, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Royal Oak, Michigan + 1 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Royal Oak", "state": "Michigan" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00818493" }, { "nct_id": "NCT04910048", "title": "Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Osteoarthritis, Knee", "Osteoarthritis, Hip", "Avascular Necrosis", "Rheumatoid Arthritis" ], "interventions": [ { "name": "POPOP (preoperative patient optimization program)", "type": "OTHER" }, { "name": "SOC (standard of care)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Arkansas", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 46, "start_date": "2022-01-17", "completion_date": "2024-09-03", "has_results": false, "last_update_posted_date": "2024-09-19", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 1, "location_summary": "Little Rock, Arkansas", "locations": [ { "city": "Little Rock", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04910048" }, { "nct_id": "NCT07138898", "title": "Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rheumatic Disease" ], "interventions": [ { "name": "Methotrexate", "type": "DRUG" }, { "name": "Sulfasalazine", "type": "DRUG" }, { "name": "Hydroxychloroquine", "type": "DRUG" }, { "name": "Leflunomide", "type": "DRUG" }, { "name": "Azathioprine", "type": "DRUG" }, { "name": "Mycophenolate", "type": "DRUG" }, { "name": "Cyclosporine", "type": "DRUG" }, { "name": "Tacrolimus", "type": "DRUG" }, { "name": "Etanercept", "type": "DRUG" }, { "name": "Adalimumab", "type": "DRUG" }, { "name": "Golimumab", "type": "DRUG" }, { "name": "Certolizumab", "type": "DRUG" }, { "name": "Infliximab", "type": "DRUG" }, { "name": "Rituximab", "type": "BIOLOGICAL" }, { "name": "Belimumab", "type": "BIOLOGICAL" }, { "name": "Tocilizumab", "type": "BIOLOGICAL" }, { "name": "Anakinra", "type": "BIOLOGICAL" }, { "name": "Canakinumab", "type": "BIOLOGICAL" }, { "name": "Abatacept", "type": "BIOLOGICAL" }, { "name": "Secukinumab", "type": "BIOLOGICAL" }, { "name": "Ixekizumab", "type": "BIOLOGICAL" }, { "name": "Bimekizumab", "type": "BIOLOGICAL" }, { "name": "Ustekinumab", "type": "BIOLOGICAL" }, { "name": "Guselkumab", "type": "BIOLOGICAL" }, { "name": "Risankizumab", "type": "BIOLOGICAL" }, { "name": "Tofacitinib", "type": "DRUG" }, { "name": "Upadacitinib", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 80, "start_date": "2025-12-12", "completion_date": "2028-01", "has_results": false, "last_update_posted_date": "2026-07-09", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07138898" }, { "nct_id": "NCT01984190", "title": "Multicenter Registry for Effectiveness Analysis of ActiveCare+S.F.T® Mobile Compression Device for Thrombosis Prevention in Hip and Knee Arthroplasty", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Venous Thromboembolism" ], "interventions": [], "intervention_types": [], "sponsor": "Medical Compression Systems", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 411, "start_date": "2011-04", "completion_date": "2011-10", "has_results": false, "last_update_posted_date": "2014-09-04", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 10, "location_summary": "Little Rock, Alaska • La Jolla, California • Menlo Park, California + 7 more", "locations": [ { "city": "Little Rock", "state": "Alaska" }, { "city": "La Jolla", "state": "California" }, { "city": "Menlo Park", "state": "California" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Edina", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT01984190" }, { "nct_id": "NCT03275610", "title": "Genetic Markers of Patients With History of Pulmonary Embolism Post Total Joint Arthroplasty", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pulmonary Embolism" ], "interventions": [ { "name": "Blood sample", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "University of Southern California", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 100, "start_date": "2017-04-24", "completion_date": "2035-04-23", "has_results": false, "last_update_posted_date": "2026-05-04", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03275610" }, { "nct_id": "NCT03665727", "title": "Psychosocial Support for Pre-operative Pain and Distress", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Pain" ], "interventions": [ { "name": "Mindfulness", "type": "BEHAVIORAL" }, { "name": "Suggestion", "type": "BEHAVIORAL" }, { "name": "Psychoeducation", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 727, "start_date": "2018-06-04", "completion_date": "2019-09-23", "has_results": false, "last_update_posted_date": "2020-05-27", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT03665727" }, { "nct_id": "NCT03443284", "title": "Health Partner Evaluation at Providence", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Total Knee Arthroplasty; Total Hip Arthroplasty" ], "interventions": [ { "name": "Health Partner", "type": "BEHAVIORAL" }, { "name": "Standard Care", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "DePuy Orthopaedics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 79, "start_date": "2018-12-11", "completion_date": "2019-12-17", "has_results": false, "last_update_posted_date": "2020-01-02", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 3, "location_summary": "Newberg, Oregon • Spokane, Washington", "locations": [ { "city": "Newberg", "state": "Oregon" }, { "city": "Spokane", "state": "Washington" }, { "city": "Spokane", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT03443284" }, { "nct_id": "NCT04203732", "title": "Evaluation of Anesthetic Techniques in Outpatient Total Joint Replacement Surgery in an Integrated Health Care Delivery System", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Anesthesia Morbidity", "Osteoarthritis, Knee", "Osteoarthritis, Hip" ], "interventions": [ { "name": "Anesthesia Type", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Kaiser Permanente", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 12466, "start_date": "2020-01-01", "completion_date": "2020-12-31", "has_results": false, "last_update_posted_date": "2021-04-09", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 1, "location_summary": "South San Francisco, California", "locations": [ { "city": "South San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04203732" }, { "nct_id": "NCT02638623", "title": "Does Fluid Replacement From Preoperative NPO Status Improve Postoperative Recovery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Osteoarthritis" ], "interventions": [ { "name": "Lactated Ringer", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "West Virginia University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 52, "start_date": "2015-10", "completion_date": "2016-12", "has_results": true, "last_update_posted_date": "2020-11-20", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 1, "location_summary": "Morgantown, West Virginia", "locations": [ { "city": "Morgantown", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02638623" }, { "nct_id": "NCT03016078", "title": "Self-adherent Absorbent Silver Dressing in Adults After Hip or Knee Arthroplasty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Arthroplasties, Hip Replacement", "Arthroplasties, Knee Replacement" ], "interventions": [ { "name": "Mepilex Border Post-Op Ag", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Molnlycke Health Care AB", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 21, "start_date": "2017-02-01", "completion_date": "2017-04-07", "has_results": true, "last_update_posted_date": "2018-02-14", "last_synced_at": "2026-10-13T13:09:19.240Z", "location_count": 1, "location_summary": "Gilbert, Arizona", "locations": [ { "city": "Gilbert", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03016078" } ] }