{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trazodone", "query": { "intervention": "Trazodone" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 36, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trazodone&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-17T01:13:15.088Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07210606", "title": "Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Sleep Disordered Breathing", "Able Bodied" ], "interventions": [ { "name": "Trazodone + positive airway pressure (PAP) therapy", "type": "DRUG" }, { "name": "Oxygen + positive airway pressure (PAP) therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 200, "start_date": "2026-09-16", "completion_date": "2030-12-31", "has_results": false, "last_update_posted_date": "2026-10-13", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 1, "location_summary": "Detroit, Michigan", "locations": [ { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT07210606" }, { "nct_id": "NCT02655354", "title": "A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Posttraumatic Stress Disorder", "Depression", "Alcohol-Related Disorders", "Suicidal Ideation", "Substance-Related Disorders", "Mild Cognitive Impairment", "Quality of Life", "Pain", "Wounds and Injury", "Brain Injuries", "Chronic Disease" ], "interventions": [ { "name": "Motivational Interviewing", "type": "BEHAVIORAL" }, { "name": "Cognitive Behavioral Therapy Elements", "type": "BEHAVIORAL" }, { "name": "Care Management", "type": "BEHAVIORAL" }, { "name": "Fluoxetine", "type": "DRUG" }, { "name": "Fluvoxamine", "type": "DRUG" }, { "name": "Paroxetine", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "Citalopram", "type": "DRUG" }, { "name": "Venlafaxine", "type": "DRUG" }, { "name": "Duloxetine", "type": "DRUG" }, { "name": "Mirtazapine", "type": "DRUG" }, { "name": "Diphenhydramine", "type": "DRUG" }, { "name": "Trazodone", "type": "DRUG" }, { "name": "Prazosin", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 635, "start_date": "2015-10", "completion_date": "2019-11", "has_results": true, "last_update_posted_date": "2021-07-02", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 24, "location_summary": "Scottsdale, Arizona • Beverly Hills, California • Sacramento, California + 20 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Jose", "state": "California" }, { "city": "Torrance", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02655354" }, { "nct_id": "NCT01347541", "title": "Piloting Acute Care to Primary Care Linkage of Safety Net Patients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Posttraumatic Stress Disorder" ], "interventions": [ { "name": "Cognitive Behavioral Therapy", "type": "BEHAVIORAL" }, { "name": "Motivational Interviewing", "type": "BEHAVIORAL" }, { "name": "FDA-Approved Anti-Anxiety Medications", "type": "DRUG" }, { "name": "Standard Care Control", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4, "start_date": "2011-01", "completion_date": "2011-11", "has_results": true, "last_update_posted_date": "2021-03-10", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01347541" }, { "nct_id": "NCT06286189", "title": "Trazodone on OSA Endotypes", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Obstructive Sleep Apnea" ], "interventions": [ { "name": "Placebo oral tablet", "type": "DRUG" }, { "name": "Trazodone Hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "21 Years to 70 Years" }, "enrollment_count": 18, "start_date": "2024-01-01", "completion_date": "2026-06-01", "has_results": false, "last_update_posted_date": "2025-02-06", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06286189" }, { "nct_id": "NCT00775203", "title": "A Randomized, Double-blind, Two-arm Study Comparing the Efficacy and Safety of Trazodone Contramid® OAD and Placebo in the Treatment of Unipolar Major Depressive Disorder.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Trazodone Hydrochloride (HCl) Extended-Release Tablets", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Labopharm Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 412, "start_date": "2007-06", "completion_date": "2007-11", "has_results": true, "last_update_posted_date": "2012-04-27", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 28, "location_summary": "Birmingham, Alabama • Mesa, Arizona • Beverly Hills, California + 25 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Burbank", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00775203" }, { "nct_id": "NCT02945644", "title": "Trazodone Dose Tolerance and APAP Adherence", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Sleep Apnea, Obstructive" ], "interventions": [ { "name": "Trazodone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Louis Stokes VA Medical Center", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 45, "start_date": "2017-02-13", "completion_date": "2020-12", "has_results": false, "last_update_posted_date": "2020-05-11", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02945644" }, { "nct_id": "NCT00000179", "title": "Agitation in Alzheimer's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alzheimer Disease" ], "interventions": [ { "name": "Trazodone", "type": "DRUG" }, { "name": "Haloperidol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute on Aging (NIA)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": null, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 16, "location_summary": "Los Angeles, California • San Diego, California • Miami, Florida + 12 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Tampa", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000179" }, { "nct_id": "NCT01030874", "title": "Orthostatic Hypotension Treatment on Rehab Unit", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Orthostatic Hypotension", "Falls" ], "interventions": [ { "name": "Medication review", "type": "OTHER" }, { "name": "Nutrition/Salt intake", "type": "OTHER" }, { "name": "Education", "type": "OTHER" }, { "name": "Exercise", "type": "OTHER" }, { "name": "Drug Recommendations", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 356, "start_date": "2011-10", "completion_date": "2016-05", "has_results": true, "last_update_posted_date": "2021-07-01", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT01030874" }, { "nct_id": "NCT05071612", "title": "Parallel Arm Trial of AD109 and AD504 In Patients With OSA", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "OSA - Obstructive Sleep Apnea" ], "interventions": [ { "name": "AD109", "type": "DRUG" }, { "name": "AD504", "type": "DRUG" }, { "name": "Atomoxetine Hydrochloride", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Apnimed", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 294, "start_date": "2021-11-29", "completion_date": "2022-08-03", "has_results": true, "last_update_posted_date": "2026-08-12", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 25, "location_summary": "Los Angeles, California • San Diego, California • Santa Ana, California + 21 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Santa Ana", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Brandon", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05071612" }, { "nct_id": "NCT05293600", "title": "Rescue Pharmacotherapy for OSA", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Obstructive Sleep Apnea" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Acetazolamide", "type": "DRUG" }, { "name": "Trazodone", "type": "DRUG" }, { "name": "Atomoxetine and eszopiclone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "21 Years to 70 Years" }, "enrollment_count": 70, "start_date": "2023-07-01", "completion_date": "2026-10-30", "has_results": false, "last_update_posted_date": "2026-07-15", "last_synced_at": "2026-10-17T01:13:15.088Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05293600" } ] }