{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trazodone&page=2",
    "query": {
      "intervention": "Trazodone",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 36,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trazodone&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trazodone&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-17T01:56:36.233Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02118688",
      "title": "Efficacy and Safety of Risperidone and Trazodone Monotherapy and Combination Therapy in Critically Ill Patients With Delirium",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Delirium",
        "Agitation"
      ],
      "interventions": [
        {
          "name": "Risperidone",
          "type": "DRUG"
        },
        {
          "name": "Trazodone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rochester General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2011-03",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2019-09-10",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02118688"
    },
    {
      "nct_id": "NCT00253890",
      "title": "Insomnia and Drug Relapse Risk",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Poor Quality Sleep",
        "Opiate Addiction"
      ],
      "interventions": [
        {
          "name": "Trazodone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Butler Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 137,
      "start_date": "2005-10",
      "completion_date": "2010-05",
      "has_results": true,
      "last_update_posted_date": "2013-12-11",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00253890"
    },
    {
      "nct_id": "NCT04468776",
      "title": "CBT-I or Zolpidem/Trazodone for Insomnia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Insomnia"
      ],
      "interventions": [
        {
          "name": "Zolpidem",
          "type": "DRUG"
        },
        {
          "name": "Internet Cognitive Behavioral Therapy for Insomnia (CBT-I)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Trazodone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "California Pacific Medical Center Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 155,
      "start_date": "2022-02-25",
      "completion_date": "2024-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-02-24",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 7,
      "location_summary": "Birmingham, Alabama • Tucson, Arizona • Columbia, Missouri + 4 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04468776"
    },
    {
      "nct_id": "NCT02922894",
      "title": "Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sleep Apnea",
        "Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Acute episodic hypoxia",
          "type": "PROCEDURE"
        },
        {
          "name": "Supplemental oxygen",
          "type": "PROCEDURE"
        },
        {
          "name": "Trazodone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Sham",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "John D. Dingell VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 100,
      "start_date": "2017-06-09",
      "completion_date": "2027-01-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02922894"
    },
    {
      "nct_id": "NCT01651442",
      "title": "Sequenced Therapies for Comorbid and Primary Insomnias",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia Comorbid to Psychiatric Disorder",
        "Primary Insomnia"
      ],
      "interventions": [
        {
          "name": "Behavioral Insomnia Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Zolpidem",
          "type": "DRUG"
        },
        {
          "name": "Trazodone",
          "type": "DRUG"
        },
        {
          "name": "Cognitive Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Jack Edinger, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 211,
      "start_date": "2012-08-01",
      "completion_date": "2017-03-01",
      "has_results": true,
      "last_update_posted_date": "2021-03-29",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01651442"
    },
    {
      "nct_id": "NCT00270959",
      "title": "Patient-Centered Collaborative Care for Preventing Post-Traumatic Stress Disorder After Traumatic Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Post-Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Motivational Interviewing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "FDA-Approved Anti-Anxiety Medications",
          "type": "DRUG"
        },
        {
          "name": "Standard Care Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 207,
      "start_date": "2006-06",
      "completion_date": "2013-03",
      "has_results": false,
      "last_update_posted_date": "2020-11-04",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00270959"
    },
    {
      "nct_id": "NCT01857596",
      "title": "Phase 1b/2a Unblinded Study of Responses in Premenopausal Women With HSDD to Lorexys Evaluating Efficacy and Safety",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hypoactive Sexual Desire Disorder (DSM-IV-TR Defined)",
        "Sexual Interest/Arousal Disorder (DSM-5 Defined)"
      ],
      "interventions": [
        {
          "name": "bupropion, Lorexys low-dose, Lorexys moderate-dose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "S1 Biopharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 50 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2013-04",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2014-10-28",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 2,
      "location_summary": "Beachwood, Ohio • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Beachwood",
          "state": "Ohio"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01857596"
    },
    {
      "nct_id": "NCT00027053",
      "title": "Trazodone for Sleep Disturbance in Early Alcohol Recovery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alcoholism"
      ],
      "interventions": [
        {
          "name": "Trazodone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rhode Island Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 173,
      "start_date": "2002-06",
      "completion_date": "2006-06",
      "has_results": false,
      "last_update_posted_date": "2010-05-13",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00027053"
    },
    {
      "nct_id": "NCT01468038",
      "title": "A Double-blind Placebo Controlled Trial of Sentra PM, a Medical Food",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Sleep Disorder"
      ],
      "interventions": [
        {
          "name": "Trazodone",
          "type": "DRUG"
        },
        {
          "name": "Sentra PM",
          "type": "OTHER"
        },
        {
          "name": "Sentra PM and Trazodone (CoPack Kit Trazamine)",
          "type": "DRUG"
        },
        {
          "name": "Placebo trazodone and placebo Sentra PM",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Targeted Medical Pharma",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 111,
      "start_date": "2008-04",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2011-11-09",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01468038"
    },
    {
      "nct_id": "NCT05085808",
      "title": "RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Delirium",
        "Morality",
        "Quality of Life",
        "Psych",
        "Treatment Side Effects"
      ],
      "interventions": [
        {
          "name": "Trazodone",
          "type": "DRUG"
        },
        {
          "name": "Quetiapine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2028-03-01",
      "completion_date": "2030-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-10-17T01:56:36.233Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05085808"
    }
  ]
}