{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+based+on+Molecular+Profiling", "query": { "intervention": "Treatment based on Molecular Profiling" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 32, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+based+on+Molecular+Profiling&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-11T11:29:57.459Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00764322", "title": "Studying Blood Samples From Women With Breast Cancer or Ductal Carcinoma In Situ Who Are Receiving Tamoxifen", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Breast Cancer", "Menopausal Symptoms" ], "interventions": [ { "name": "tamoxifen citrate", "type": "DRUG" }, { "name": "gene expression analysis", "type": "GENETIC" }, { "name": "pharmacogenomic studies", "type": "OTHER" }, { "name": "questionnaire administration", "type": "OTHER" }, { "name": "quality-of-life assessment", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "GENETIC", "OTHER", "PROCEDURE" ], "sponsor": "UNC Lineberger Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "120 Years", "sex": "FEMALE", "summary": "21 Years to 120 Years · Female only" }, "enrollment_count": 501, "start_date": "2008-06-18", "completion_date": "2011-07-01", "has_results": true, "last_update_posted_date": "2017-08-01", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 7, "location_summary": "Chapel Hill, North Carolina • Charlotte, North Carolina • Durham, North Carolina + 4 more", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" }, { "city": "Charlotte", "state": "North Carolina" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Greensboro", "state": "North Carolina" }, { "city": "Greenville", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00764322" }, { "nct_id": "NCT01280643", "title": "Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Metastatic Colorectal Cancer" ], "interventions": [ { "name": "fluorouracil", "type": "DRUG" }, { "name": "leucovorin calcium", "type": "DRUG" }, { "name": "oxaliplatin", "type": "DRUG" }, { "name": "irinotecan hydrochloride", "type": "DRUG" }, { "name": "bevacizumab", "type": "BIOLOGICAL" }, { "name": "cetuximab", "type": "BIOLOGICAL" }, { "name": "capecitabine", "type": "DRUG" }, { "name": "mutation analysis", "type": "GENETIC" }, { "name": "gene expression analysis", "type": "GENETIC" }, { "name": "laboratory biomarker analysis", "type": "OTHER" }, { "name": "immunohistochemistry staining method", "type": "OTHER" }, { "name": "nucleic acid sequencing", "type": "GENETIC" }, { "name": "protein expression analysis", "type": "GENETIC" }, { "name": "polymerase chain reaction", "type": "GENETIC" }, { "name": "DNA analysis", "type": "GENETIC" } ], "intervention_types": [ "DRUG", "BIOLOGICAL", "GENETIC", "OTHER" ], "sponsor": "Fox Chase Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3, "start_date": "2010-03", "completion_date": "2014-05", "has_results": true, "last_update_posted_date": "2021-03-15", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01280643" }, { "nct_id": "NCT00897663", "title": "Improving the Selection of Patients With Glioblastoma Multiforme for Treatment With Epidermal Growth Factor Receptor Inhibitor Therapies", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Brain and Central Nervous System Tumors" ], "interventions": [ { "name": "gene expression analysis", "type": "GENETIC" }, { "name": "microarray analysis", "type": "GENETIC" }, { "name": "protein expression analysis", "type": "GENETIC" }, { "name": "diagnostic laboratory biomarker analysis", "type": "OTHER" }, { "name": "immunohistochemistry staining method", "type": "OTHER" } ], "intervention_types": [ "GENETIC", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 56, "start_date": "2006-11", "completion_date": "2018-01", "has_results": false, "last_update_posted_date": "2018-01-24", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 10, "location_summary": "Scottsdale, Arizona • Jacksonville, Florida • Sioux City, Iowa + 3 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Sioux City", "state": "Iowa" }, { "city": "Sioux City", "state": "Iowa" }, { "city": "Sioux City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT00897663" }, { "nct_id": "NCT01827384", "title": "MPACT Study to Compare Effects of Targeted Drugs on Tumor Gene Variations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Advanced Malignant Solid Neoplasm" ], "interventions": [ { "name": "Adavosertib", "type": "DRUG" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Everolimus", "type": "DRUG" }, { "name": "Temozolomide", "type": "DRUG" }, { "name": "Trametinib", "type": "DRUG" }, { "name": "Veliparib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 208, "start_date": "2014-01-07", "completion_date": "2021-10-08", "has_results": true, "last_update_posted_date": "2023-09-29", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 8, "location_summary": "Aurora, Colorado • Atlanta, Georgia • Lexington, Kentucky + 5 more", "locations": [ { "city": "Aurora", "state": "Colorado" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Lexington", "state": "Kentucky" }, { "city": "Bethesda", "state": "Maryland" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT01827384" }, { "nct_id": "NCT00686842", "title": "PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Kaposi's Sarcoma" ], "interventions": [ { "name": "VEGF inhibitor PTC299", "type": "DRUG" }, { "name": "gene expression analysis", "type": "GENETIC" }, { "name": "polymerase chain reaction", "type": "GENETIC" }, { "name": "protein expression analysis", "type": "GENETIC" }, { "name": "immunohistochemistry staining method", "type": "OTHER" }, { "name": "laboratory biomarker analysis", "type": "OTHER" }, { "name": "pharmacological study", "type": "OTHER" }, { "name": "biopsy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "GENETIC", "OTHER", "PROCEDURE" ], "sponsor": "AIDS Malignancy Consortium", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 17, "start_date": "2008-09", "completion_date": "2010-12", "has_results": true, "last_update_posted_date": "2018-06-06", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 8, "location_summary": "La Jolla, California • Los Angeles, California • Honolulu, Hawaii + 4 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Honolulu", "state": "Hawaii" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00686842" }, { "nct_id": "NCT01074814", "title": "Pilot Study Using Molecular Profiling to Find Potential Targets & Select Treatments for Pts With Met br ca", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Metastatic Breast Cancer" ], "interventions": [ { "name": "Approved therapy will be assigned based on molecular profile and RPMA results", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Translational Drug Development", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2010-03", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2023-09-28", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 3, "location_summary": "Scottsdale, Arizona • Fairfax, Virginia • Spokane, Washington", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Fairfax", "state": "Virginia" }, { "city": "Spokane", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01074814" }, { "nct_id": "NCT02437617", "title": "Genomic Profiling Assay in Phase I", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Advanced Cancers" ], "interventions": [ { "name": "Tumor Tissue", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 500, "start_date": "2012-07-13", "completion_date": "2021-06-01", "has_results": false, "last_update_posted_date": "2021-06-14", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02437617" }, { "nct_id": "NCT03739372", "title": "Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Glioma", "Glioma of Brain", "Cancer", "Pediatric Cancer", "Pediatric Brain Tumor", "Astrocytoma", "Glioblastoma", "Hemispheric" ], "interventions": [ { "name": "Specialized tumor board recommendation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 44, "start_date": "2018-11-28", "completion_date": "2026-05-01", "has_results": false, "last_update_posted_date": "2026-08-11", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 12, "location_summary": "San Diego, California • San Francisco, California • Washington D.C., District of Columbia + 9 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT03739372" }, { "nct_id": "NCT03322995", "title": "Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pancreatic Cancer" ], "interventions": [ { "name": "First-line Chemotherapy", "type": "DRUG" }, { "name": "Second-line Chemotherapy", "type": "DRUG" }, { "name": "Chemoradiation", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 125, "start_date": "2018-06-21", "completion_date": "2032-06-01", "has_results": false, "last_update_posted_date": "2026-01-08", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT03322995" }, { "nct_id": "NCT00737243", "title": "Treatment Based on Molecular Profiling Diagnosis Carcinoma of Unknown Primary Site", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Carcinoma" ], "interventions": [ { "name": "Paclitaxel", "type": "DRUG" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Bevacizumab", "type": "DRUG" }, { "name": "Erlotinib", "type": "DRUG" }, { "name": "Treatment determined by physician", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "SCRI Development Innovations, LLC", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 289, "start_date": "2008-08", "completion_date": "2012-12", "has_results": true, "last_update_posted_date": "2016-08-17", "last_synced_at": "2026-09-11T11:29:57.459Z", "location_count": 21, "location_summary": "Huntsville, Alabama • Fort Myers, Florida • Jacksonville, Florida + 18 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Lakeland", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00737243" } ] }