{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+based+on+Molecular+Profiling&page=2", "query": { "intervention": "Treatment based on Molecular Profiling", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 32, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+based+on+Molecular+Profiling&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+based+on+Molecular+Profiling&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-01T08:23:45.343Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01488552", "title": "Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Stage IV Pancreatic Cancer" ], "interventions": [ { "name": "Gemcitabine", "type": "DRUG" }, { "name": "nab-paclitaxel", "type": "DRUG" }, { "name": "FOLFIRINOX", "type": "DRUG" }, { "name": "Immunohistochemistry (IHC) Analysis", "type": "GENETIC" }, { "name": "Metformin", "type": "DRUG" }, { "name": "mFOLFIRI", "type": "DRUG" } ], "intervention_types": [ "DRUG", "GENETIC" ], "sponsor": "Pancreatic Cancer Research Team", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2011-11", "completion_date": "2016-08", "has_results": false, "last_update_posted_date": "2016-08-18", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 5, "location_summary": "Scottsdale, Arizona • Burbank, California • Minneapolis, Minnesota + 2 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Burbank", "state": "California" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Seattle", "state": "Washington" }, { "city": "Spokane", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01488552" }, { "nct_id": "NCT00898742", "title": "Gene and Protein Expression Patterns in Predicting Response to Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Head and Neck Cancer" ], "interventions": [ { "name": "DNA and tissue microarray analysis", "type": "GENETIC" }, { "name": "reverse transcriptase-polymerase chain reaction", "type": "GENETIC" }, { "name": "mass spectrometry", "type": "OTHER" } ], "intervention_types": [ "GENETIC", "OTHER" ], "sponsor": "Vanderbilt-Ingram Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 58, "start_date": "2007-04", "completion_date": "2010-06", "has_results": false, "last_update_posted_date": "2013-04-02", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 3, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" }, { "city": "Nashville", "state": "Tennessee" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00898742" }, { "nct_id": "NCT02551718", "title": "High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Recurrent Acute Leukemia of Ambiguous Lineage", "Recurrent Acute Lymphoblastic Leukemia", "Recurrent Acute Myeloid Leukemia", "Refractory Acute Lymphoblastic Leukemia", "Refractory Acute Myeloid Leukemia", "Refractory Acute Leukemia of Ambiguous Lineage" ], "interventions": [ { "name": "Chemosensitivity Assay", "type": "OTHER" }, { "name": "Cytology Specimen Collection Procedure", "type": "OTHER" }, { "name": "Gene Expression Analysis", "type": "GENETIC" }, { "name": "Genetic Variation Analysis", "type": "GENETIC" }, { "name": "In Vitro Sensitivity-Directed Chemotherapy", "type": "DRUG" } ], "intervention_types": [ "OTHER", "GENETIC", "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": null, "sex": "ALL", "summary": "3 Years and older" }, "enrollment_count": 34, "start_date": "2015-09-11", "completion_date": "2021-05-13", "has_results": true, "last_update_posted_date": "2022-06-30", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT02551718" }, { "nct_id": "NCT02780128", "title": "Next Generation Personalized Neuroblastoma Therapy", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Neuroblastoma", "Cancer" ], "interventions": [ { "name": "Biopsy", "type": "PROCEDURE" }, { "name": "Next Generation Sequencing", "type": "GENETIC" }, { "name": "Tumor Scans", "type": "PROCEDURE" }, { "name": "Bone marrow Tests", "type": "PROCEDURE" }, { "name": "Physical Exam", "type": "OTHER" }, { "name": "Eye Exam", "type": "OTHER" }, { "name": "Labs", "type": "OTHER" }, { "name": "Pregnancy Test", "type": "OTHER" }, { "name": "Interviews", "type": "BEHAVIORAL" }, { "name": "ECG", "type": "OTHER" }, { "name": "Echocardiogram", "type": "OTHER" }, { "name": "Ribociclib", "type": "DRUG" }, { "name": "Ceritinib", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "GENETIC", "OTHER", "BEHAVIORAL", "DRUG" ], "sponsor": "Yael P Mosse", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "21 Years", "sex": "ALL", "summary": "1 Year to 21 Years" }, "enrollment_count": 66, "start_date": "2016-07", "completion_date": "2022-08", "has_results": false, "last_update_posted_date": "2026-03-10", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02780128" }, { "nct_id": "NCT00545948", "title": "Adjuvant Cisplatin With Either Genomic-Guided Vinorelbine or Pemetrexed for Early Stage Non-Small-Cell Lung Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Carcinoma, Non-Small-Cell Lung" ], "interventions": [ { "name": "Vinorelbine followed by Cisplatin", "type": "DRUG" }, { "name": "Pemetrexed followed by Cisplatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 31, "start_date": "2007-12", "completion_date": "2012-01", "has_results": true, "last_update_posted_date": "2014-07-21", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 13, "location_summary": "West Palm Beach, Florida • Chicago, Illinois • Charlotte, North Carolina + 10 more", "locations": [ { "city": "West Palm Beach", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Charlotte", "state": "North Carolina" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Henderson", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00545948" }, { "nct_id": "NCT02470819", "title": "Genomic and Proteomic Profiling Targets Influenced Treatment in Metastatic Breast Cancer", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Metastatic Breast Cancer", "Breast Tumor", "Advanced Gynecologic Cancer" ], "interventions": [ { "name": "Genetic profiling", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Avera McKennan Hospital & University Health Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2014-03", "completion_date": "2018-10-30", "has_results": false, "last_update_posted_date": "2018-11-07", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 1, "location_summary": "Sioux Falls, South Dakota", "locations": [ { "city": "Sioux Falls", "state": "South Dakota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02470819" }, { "nct_id": "NCT01074814", "title": "Pilot Study Using Molecular Profiling to Find Potential Targets & Select Treatments for Pts With Met br ca", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Metastatic Breast Cancer" ], "interventions": [ { "name": "Approved therapy will be assigned based on molecular profile and RPMA results", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Translational Drug Development", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2010-03", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2023-09-28", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 3, "location_summary": "Scottsdale, Arizona • Fairfax, Virginia • Spokane, Washington", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Fairfax", "state": "Virginia" }, { "city": "Spokane", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01074814" }, { "nct_id": "NCT02272595", "title": "Rational Therapeutics Based on Matched Tumor and Normal Tissue", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Advanced Cancers" ], "interventions": [ { "name": "Treatment Based on Genetic Mutation", "type": "OTHER" }, { "name": "Treatment Based on No Genetic Mutation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3, "start_date": "2014-11-04", "completion_date": "2022-01-11", "has_results": false, "last_update_posted_date": "2022-02-15", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02272595" }, { "nct_id": "NCT01280643", "title": "Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Metastatic Colorectal Cancer" ], "interventions": [ { "name": "fluorouracil", "type": "DRUG" }, { "name": "leucovorin calcium", "type": "DRUG" }, { "name": "oxaliplatin", "type": "DRUG" }, { "name": "irinotecan hydrochloride", "type": "DRUG" }, { "name": "bevacizumab", "type": "BIOLOGICAL" }, { "name": "cetuximab", "type": "BIOLOGICAL" }, { "name": "capecitabine", "type": "DRUG" }, { "name": "mutation analysis", "type": "GENETIC" }, { "name": "gene expression analysis", "type": "GENETIC" }, { "name": "laboratory biomarker analysis", "type": "OTHER" }, { "name": "immunohistochemistry staining method", "type": "OTHER" }, { "name": "nucleic acid sequencing", "type": "GENETIC" }, { "name": "protein expression analysis", "type": "GENETIC" }, { "name": "polymerase chain reaction", "type": "GENETIC" }, { "name": "DNA analysis", "type": "GENETIC" } ], "intervention_types": [ "DRUG", "BIOLOGICAL", "GENETIC", "OTHER" ], "sponsor": "Fox Chase Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3, "start_date": "2010-03", "completion_date": "2014-05", "has_results": true, "last_update_posted_date": "2021-03-15", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01280643" }, { "nct_id": "NCT07342582", "title": "The Rhinovirus Hospitalization and Investigation of Nasal-airway Omics (RHINO) Study", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rhinovirus" ], "interventions": [ { "name": "Nasal Swab Healthy Surveillance", "type": "DIAGNOSTIC_TEST" }, { "name": "Nasal Swab Sick Samples", "type": "DIAGNOSTIC_TEST" }, { "name": "Nasal Swab Hospitalized Cohort", "type": "DIAGNOSTIC_TEST" }, { "name": "Sick Follow-up Survey", "type": "OTHER" }, { "name": "Older Cohort Control Group", "type": "OTHER" }, { "name": "Procedural Comfort or Care", "type": "OTHER" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "OTHER" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": "17 Years", "sex": "ALL", "summary": "Up to 17 Years" }, "enrollment_count": 670, "start_date": "2026-08-04", "completion_date": "2030-05", "has_results": false, "last_update_posted_date": "2026-08-10", "last_synced_at": "2026-10-01T08:23:45.343Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT07342582" } ] }