{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+modification",
    "query": {
      "intervention": "Treatment modification"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6553,
    "total_pages": 656,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+modification&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T05:41:10.788Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05473013",
      "title": "Optimizing Digital Health Technology Interventions to Increase Skill Acquisition and Utilization",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bulimia Nervosa",
        "Bulimia",
        "Binge Eating",
        "Binge-Eating Disorder"
      ],
      "interventions": [
        {
          "name": "Behavioral Therapy for Eating Disorders",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Skills Monitoring On",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated Reminder Messages",
          "type": "BEHAVIORAL"
        },
        {
          "name": "JITAIs",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Nemours Children's Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 264,
      "start_date": "2023-01-06",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 1,
      "location_summary": "Wilmington, Delaware",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05473013"
    },
    {
      "nct_id": "NCT07149870",
      "title": "Pain Management Teams Using Whole Health to Optimize Function and Safety in Veterans: The TEAMWORK Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Pain Management Team + Whole Health Coach (PMT-WHC)",
          "type": "OTHER"
        },
        {
          "name": "Pain Management Team-Usual Care (PMT-UC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 432,
      "start_date": "2025-11-20",
      "completion_date": "2029-10-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-17",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 5,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Aurora, Colorado + 2 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "West Haven",
          "state": "Connecticut"
        },
        {
          "city": "Boise",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07149870"
    },
    {
      "nct_id": "NCT06233656",
      "title": "Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Spinal Cord Injuries"
      ],
      "interventions": [
        {
          "name": "Acceptance and commitment therapy (ACT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 140,
      "start_date": "2024-04-30",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-02-05",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06233656"
    },
    {
      "nct_id": "NCT01985022",
      "title": "Changing Developmental Trajectories Through Early Treatment",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorders"
      ],
      "interventions": [
        {
          "name": "Group-ESI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Individual-ESI",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "9 Months",
        "maximum_age": "24 Months",
        "sex": "ALL",
        "summary": "9 Months to 24 Months"
      },
      "enrollment_count": 33,
      "start_date": "2013-05",
      "completion_date": "2019-11-26",
      "has_results": true,
      "last_update_posted_date": "2023-06-09",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01985022"
    },
    {
      "nct_id": "NCT05015491",
      "title": "Effects of Online App Weight Loss Programs on Liver Health in Obese Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "NASH",
        "Fatty Liver",
        "NAFLD",
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "Noom Healthy Weight Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Noom Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2021-08-09",
      "completion_date": "2022-09-12",
      "has_results": false,
      "last_update_posted_date": "2023-11-13",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 1,
      "location_summary": "Chandler, Arizona",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05015491"
    },
    {
      "nct_id": "NCT03664310",
      "title": "Transdiagnostic Sleep and Anxiety Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety Disorders"
      ],
      "interventions": [
        {
          "name": "FSET Anxiety and Sleep Treatment",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 61,
      "start_date": "2017-08-01",
      "completion_date": "2018-05-12",
      "has_results": false,
      "last_update_posted_date": "2021-02-01",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03664310"
    },
    {
      "nct_id": "NCT06923423",
      "title": "Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PTSD - Post Traumatic Stress Disorder",
        "PTSD and Alcohol Use Disorder",
        "PTSD and Trauma-related Symptoms",
        "Substance Use Disorder (SUD)",
        "Depression",
        "Mental Health",
        "Trauma",
        "Trauma Exposure",
        "Traumatic Stress Disorder",
        "Traumatic Stress",
        "Post Traumatic Stress Symptoms"
      ],
      "interventions": [
        {
          "name": "Group Cognitive Processing Therapy (CPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Group Individual trauma focused self-help via workbook",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 640,
      "start_date": "2025-07-07",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 6,
      "location_summary": "Little Rock, Arkansas • Osceola, Arkansas • Texarkana, Arkansas + 2 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Osceola",
          "state": "Arkansas"
        },
        {
          "city": "Texarkana",
          "state": "Arkansas"
        },
        {
          "city": "West Memphis",
          "state": "Arkansas"
        },
        {
          "city": "Bismarck",
          "state": "North Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06923423"
    },
    {
      "nct_id": "NCT05299554",
      "title": "Long-term Safety Study of Chronocort in the Treatment of Participants With Congenital Adrenal Hyperplasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Congenital Adrenal Hyperplasia"
      ],
      "interventions": [
        {
          "name": "Chronocort",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Immedica Pharma AB",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 76,
      "start_date": "2022-04-01",
      "completion_date": "2026-01-15",
      "has_results": false,
      "last_update_posted_date": "2026-06-18",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 11,
      "location_summary": "Los Angeles, California • Orange, California • Jacksonville, Florida + 8 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05299554"
    },
    {
      "nct_id": "NCT04298905",
      "title": "Leveraging mHealth to Enable and Adapt CHW Strategies to Improve TB/HIV Patient Outcomes in SA",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adherence, Patient",
        "TB",
        "HIV/AIDS",
        "Care Coordination"
      ],
      "interventions": [
        {
          "name": "CHW mHealth patient intervention for trigger escalation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 62,
      "start_date": "2022-03-10",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-29",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04298905"
    },
    {
      "nct_id": "NCT05507905",
      "title": "Effects of Dance and Music Appreciation on Brain Health and Fitness in People at Risk for Alzheimer's Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Music",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Dance Classes",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "62 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "62 Years and older"
      },
      "enrollment_count": 165,
      "start_date": "2023-04-24",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-09-30T05:41:10.788Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05507905"
    }
  ]
}