{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+Functional+Constipation+by",
    "query": {
      "intervention": "Treatment of Functional Constipation by"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-15T23:59:09.549Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01416909",
      "title": "Managing Medication-induced Constipation in Cancer: A Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Constipation"
      ],
      "interventions": [
        {
          "name": "Laxative Treatment",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        },
        {
          "name": "Assessment Questionnaires",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 601,
      "start_date": "2008-11",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2017-02-23",
      "last_synced_at": "2026-09-15T23:59:09.549Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01416909"
    },
    {
      "nct_id": "NCT04759833",
      "title": "A Study of Prucalopride For Functional Constipation in Children and Teenagers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Constipation"
      ],
      "interventions": [
        {
          "name": "Prucalopride",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Takeda",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Months to 17 Years"
      },
      "enrollment_count": 175,
      "start_date": "2021-07-13",
      "completion_date": "2023-11-13",
      "has_results": true,
      "last_update_posted_date": "2024-06-06",
      "last_synced_at": "2026-09-15T23:59:09.549Z",
      "location_count": 41,
      "location_summary": "Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 32 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04759833"
    },
    {
      "nct_id": "NCT05718505",
      "title": "Comparison of the Atmo Motility Gas Capsule System to the Reference Standard",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastroparesis",
        "Slow Transit Constipation",
        "IBS"
      ],
      "interventions": [
        {
          "name": "Atmo Motility Gas Capsule System",
          "type": "DEVICE"
        },
        {
          "name": "SmartPill Monitoring System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Atmo Biosciences Pty Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "22 Years to 80 Years"
      },
      "enrollment_count": 209,
      "start_date": "2023-06-05",
      "completion_date": "2024-04",
      "has_results": false,
      "last_update_posted_date": "2024-01-10",
      "last_synced_at": "2026-09-15T23:59:09.549Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05718505"
    },
    {
      "nct_id": "NCT05639556",
      "title": "Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "BMI and lean mass index from DXA",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Anthropometric Measurements",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hand-grip strength",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Six-minute walk Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sit-to-Stand Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Short physical performance battery (SPPB)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "BIA Sub-study",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Accelerometry to assess physical activity",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Gastrointestinal (GI) and nutrition questionnaires:",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: PHQ-8",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: GAD-7",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ)",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: CF Fatalism Scale",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA)",
          "type": "OTHER"
        },
        {
          "name": "12-month Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Oral glucose tolerance testing (OGTT)",
          "type": "OTHER"
        },
        {
          "name": "Continuous glucose monitoring (CGM)",
          "type": "DEVICE"
        },
        {
          "name": "Chest CT scans (When available within the past 6 months in medical records)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hologic Dual X-Ray Absorptiometry (DXA)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Ultrasound Sub-study of assessment of appendage muscles using ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Psychosocial questionnaire: Hunger Vital Sign questionnaire",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Respiratory symptom questionnaire: CRISS",
          "type": "OTHER"
        },
        {
          "name": "Spirometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Psychosocial questionnaire: Additional Health Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "CF Management Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Food Frequency Questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-04-20",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-09-15T23:59:09.549Z",
      "location_count": 23,
      "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Atlanta, Georgia + 19 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05639556"
    },
    {
      "nct_id": "NCT05579847",
      "title": "Feasibility of a Smart-Phone App for Patients With Advanced Renal Cell Carcinoma Undergoing Combination Immunotherapy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Renal Cell Carcinoma Stage IV"
      ],
      "interventions": [
        {
          "name": "mHealth Smart Phone Application",
          "type": "OTHER"
        },
        {
          "name": "eHEALS digital literacy test",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Weekly Quiz",
          "type": "BEHAVIORAL"
        },
        {
          "name": "European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Post Intervention Survey",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2022-10-19",
      "completion_date": "2024-11-04",
      "has_results": false,
      "last_update_posted_date": "2025-12-04",
      "last_synced_at": "2026-09-15T23:59:09.549Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05579847"
    },
    {
      "nct_id": "NCT02442115",
      "title": "Impact of Improving Gastrointestinal Symptoms on Autism Symptoms and Oxidative Stress",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autistic Disorder",
        "Constipation",
        "Gastrointestinal Diseases"
      ],
      "interventions": [
        {
          "name": "Treatment of Functional Constipation by",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "5 Years to 17 Years"
      },
      "enrollment_count": 100,
      "start_date": "2015-04-29",
      "completion_date": "2019-02-06",
      "has_results": false,
      "last_update_posted_date": "2024-12-20",
      "last_synced_at": "2026-09-15T23:59:09.549Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Santa Ana, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Santa Ana",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02442115"
    },
    {
      "nct_id": "NCT03821532",
      "title": "Adherence/Outcomes After Use of Constipation Action Plan",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Constipation - Functional"
      ],
      "interventions": [
        {
          "name": "Constipation Action Plan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Nemours Children's Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "4 Years to 8 Years"
      },
      "enrollment_count": 25,
      "start_date": "2016-09-13",
      "completion_date": "2018-05-01",
      "has_results": false,
      "last_update_posted_date": "2019-01-31",
      "last_synced_at": "2026-09-15T23:59:09.549Z",
      "location_count": 1,
      "location_summary": "Wilmington, Delaware",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03821532"
    },
    {
      "nct_id": "NCT04683900",
      "title": "Mediterranean Diet Intervention to Improve Gastrointestinal Function in Parkinson's Disease a Randomized, Controlled, Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Standard of care + Mediterranean diet (intervention)",
          "type": "OTHER"
        },
        {
          "name": "Standard of care (control)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 46,
      "start_date": "2021-02-08",
      "completion_date": "2022-06-07",
      "has_results": false,
      "last_update_posted_date": "2022-07-12",
      "last_synced_at": "2026-09-15T23:59:09.549Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04683900"
    }
  ]
}