{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+depression&page=17", "query": { "intervention": "Treatment of depression", "page": 17 }, "page_size": 10 }, "pagination": { "page": 17, "page_size": 10, "total_count": 3100, "total_pages": 310, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+depression&page=18&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+depression&page=16&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-15T20:42:06.811Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04306939", "title": "Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study", "overall_status": "SUSPENDED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Chronic Pancreatitis", "Inflammatory Bowel Diseases", "Hepatitis", "NASH - Nonalcoholic Steatohepatitis", "Acute Pancreatitis", "Rheumatoid Arthritis", "Diabetes Mellitus", "Dyslipidemias", "Multiple Sclerosis", "Irritable Bowel Syndrome", "Chronic Pain", "Chronic Disease", "Chronic Kidney Diseases", "Crohn Disease", "Celiac Disease", "Biliary Cirrhosis", "Bile Acid Synthesis Defect", "Gastritis", "Cholecystitis", "Cholelithiases", "IPMN", "Cyst Pancreas", "Cystic Fibrosis", "Pancreatic Exocrine Insufficiency", "Diarrhea Chronic", "Constipation - Functional", "Constipation Chronic Idiopathic" ], "interventions": [ { "name": "venipuncture", "type": "OTHER" }, { "name": "Questionnaires", "type": "BEHAVIORAL" }, { "name": "Additional Sample Collections", "type": "OTHER" } ], "intervention_types": [ "OTHER", "BEHAVIORAL" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 120000, "start_date": "2014-11-01", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-01-07", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04306939" }, { "nct_id": "NCT01998958", "title": "A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Treatment Resistant Depressive Disorder" ], "interventions": [ { "name": "Esketamine 14 mg", "type": "DRUG" }, { "name": "Esketamine 28 mg", "type": "DRUG" }, { "name": "Esketamine 56 mg", "type": "DRUG" }, { "name": "Esketamine 84 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "20 Years to 64 Years" }, "enrollment_count": 108, "start_date": "2014-01-27", "completion_date": "2015-09-25", "has_results": true, "last_update_posted_date": "2025-04-29", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 14, "location_summary": "Birmingham, Alabama • Garden Grove, California • Hartford, Connecticut + 11 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Garden Grove", "state": "California" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01998958" }, { "nct_id": "NCT01665872", "title": "New Haven MOMS Partnership", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Depression", "Stress" ], "interventions": [ { "name": "Cognitive-Behavioral Group Therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "FEMALE", "summary": "16 Years and older · Female only" }, "enrollment_count": 154, "start_date": "2012-05", "completion_date": "2017-06", "has_results": true, "last_update_posted_date": "2020-02-10", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT01665872" }, { "nct_id": "NCT01369095", "title": "Efficacy and Safety of Fixed Doses of BMS 820836 in the Treatment of Patients With Treatment Resistant Major Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Duloxetine", "type": "DRUG" }, { "name": "Escitalopram", "type": "DRUG" }, { "name": "BMS-820836 Placebo", "type": "DRUG" }, { "name": "BMS-820836", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 976, "start_date": "2011-07", "completion_date": "2013-05", "has_results": false, "last_update_posted_date": "2015-10-12", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 48, "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Chino, California + 41 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Chino", "state": "California" }, { "city": "Glendale", "state": "California" }, { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01369095" }, { "nct_id": "NCT06876129", "title": "Pharmacologic Augmentation of TMS for Depression With D-serine", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Depression" ], "interventions": [ { "name": "TMS", "type": "DEVICE" }, { "name": "D-serine", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "DRUG", "OTHER" ], "sponsor": "Mclean Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 60, "start_date": "2025-04-01", "completion_date": "2027-04-01", "has_results": false, "last_update_posted_date": "2026-05-15", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 1, "location_summary": "Belmont, Massachusetts", "locations": [ { "city": "Belmont", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06876129" }, { "nct_id": "NCT04189939", "title": "Computational Psychiatric Approach to Depression", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Depression", "Treatment Resistant Depression" ], "interventions": [ { "name": "clinical assessments", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 128, "start_date": "2020-03-09", "completion_date": "2023-07-10", "has_results": false, "last_update_posted_date": "2024-08-06", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04189939" }, { "nct_id": "NCT05645575", "title": "In-patient SCC TMS", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Open-label TMS", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 30, "start_date": "2025-04-01", "completion_date": "2027-02-22", "has_results": false, "last_update_posted_date": "2025-09-23", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05645575" }, { "nct_id": "NCT03302312", "title": "Effectiveness and Acceptability of Stellate Ganglion Block for Posttraumatic Stress Disorder Symptoms - Acceptability", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Posttraumatic Stress Disorder" ], "interventions": [], "intervention_types": [], "sponsor": "RTI International", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 54, "start_date": "2017-11-03", "completion_date": "2018-03-02", "has_results": false, "last_update_posted_date": "2018-07-30", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 2, "location_summary": "Honolulu, Hawaii • Fort Bragg, North Carolina", "locations": [ { "city": "Honolulu", "state": "Hawaii" }, { "city": "Fort Bragg", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03302312" }, { "nct_id": "NCT05841030", "title": "A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Depressive Disorder, Major" ], "interventions": [ { "name": "No Intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "74 Years", "sex": "ALL", "summary": "18 Years to 74 Years" }, "enrollment_count": 545, "start_date": "2023-04-28", "completion_date": "2026-02-27", "has_results": false, "last_update_posted_date": "2026-04-23", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 18, "location_summary": "Birmingham, Alabama • Homewood, Alabama • California City, California + 15 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Homewood", "state": "Alabama" }, { "city": "California City", "state": "California" }, { "city": "Farmington", "state": "Connecticut" }, { "city": "Saint Augustine", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05841030" }, { "nct_id": "NCT00988663", "title": "The Impact of Memantine on Electroconvulsive Therapy (ECT): Will it Improve Response and Protect Against Cognitive Problems?", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "memantine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Jerrry L Lewis", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2009-11", "completion_date": "2009-11", "has_results": false, "last_update_posted_date": "2017-03-24", "last_synced_at": "2026-10-15T20:42:06.811Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT00988663" } ] }