{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+depression&page=24",
    "query": {
      "intervention": "Treatment of depression",
      "page": 24
    },
    "page_size": 10
  },
  "pagination": {
    "page": 24,
    "page_size": 10,
    "total_count": 3100,
    "total_pages": 310,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+depression&page=25&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+depression&page=23&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-16T04:20:14.733Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01592695",
      "title": "Tailored Tobacco Quitline for Rural Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Nicotine replacement therapy - transdermal nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Tailored behavioral intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco quit line referral",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine replacement therapy - nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Bupropion Sustained Release",
          "type": "DRUG"
        },
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - transdermal nicotine patch + nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - transdermal nicotine patch + bupropion",
          "type": "DRUG"
        },
        {
          "name": "Alcohol use risk reduction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral activation for the treatment of depression",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral management of post-cessation weight gain",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Iowa City Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 63,
      "start_date": "2012-06",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2019-08-02",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01592695"
    },
    {
      "nct_id": "NCT01797575",
      "title": "N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Bipolar Disorder"
      ],
      "interventions": [
        {
          "name": "Aspirin",
          "type": "DRUG"
        },
        {
          "name": "N-acetyl-cysteine (NAC)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Sugar Pill",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 38,
      "start_date": "2013-01",
      "completion_date": "2017-02-01",
      "has_results": true,
      "last_update_posted_date": "2018-04-30",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01797575"
    },
    {
      "nct_id": "NCT03109431",
      "title": "Stepped Care for Youth Living With HIV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV",
        "Mental Health",
        "Illicit Substance Use",
        "Sexually Transmitted Infections (STI)"
      ],
      "interventions": [
        {
          "name": "Level 1",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Level 2",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Level 3",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "12 Years to 24 Years"
      },
      "enrollment_count": 170,
      "start_date": "2017-05-06",
      "completion_date": "2022-11-30",
      "has_results": false,
      "last_update_posted_date": "2022-12-06",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • New Orleans, Louisiana",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03109431"
    },
    {
      "nct_id": "NCT00001545",
      "title": "Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Bipolar Disorder",
        "Mood Disorder",
        "Unipolar Depression"
      ],
      "interventions": [
        {
          "name": "Magstim Super Rapid Magnetic Stimulator",
          "type": "DEVICE"
        },
        {
          "name": "Cadwell MES-10",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 91,
      "start_date": "1996-05",
      "completion_date": "2006-07",
      "has_results": false,
      "last_update_posted_date": "2006-07-13",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001545"
    },
    {
      "nct_id": "NCT04399629",
      "title": "Trial of PCIT-ED in School for Preschoolers in Poverty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Childhood Mental Disorder"
      ],
      "interventions": [
        {
          "name": "PCIT-ED",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Parenting Wisely",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "48 Months",
        "maximum_age": "83 Months",
        "sex": "ALL",
        "summary": "48 Months to 83 Months"
      },
      "enrollment_count": 62,
      "start_date": "2019-09-26",
      "completion_date": "2021-01-19",
      "has_results": false,
      "last_update_posted_date": "2021-04-06",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04399629"
    },
    {
      "nct_id": "NCT05424224",
      "title": "Using rTMS to Treat Depression",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "MagVita",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Florida International University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-01-09",
      "completion_date": "2027-09-25",
      "has_results": false,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05424224"
    },
    {
      "nct_id": "NCT00203723",
      "title": "Use of Risperidone in ECT for Treatment Resistant Depression",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Major Depression"
      ],
      "interventions": [
        {
          "name": "Risperidone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 45,
      "start_date": "2005-03",
      "completion_date": "2006-05",
      "has_results": false,
      "last_update_posted_date": "2006-05-18",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00203723"
    },
    {
      "nct_id": "NCT01874951",
      "title": "Low-Dose Naltrexone (LDN) for Depression Relapse and Recurrence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Major Depressive Disorder",
        "Depression, Unipolar",
        "Recurrence",
        "Relapse"
      ],
      "interventions": [
        {
          "name": "Naltrexone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 12,
      "start_date": "2013-06",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2017-02-24",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01874951"
    },
    {
      "nct_id": "NCT00733980",
      "title": "A Study of the Effects of a New Antidepressant Treatment (GSK561679) in Females With Major Depressive Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Depressive Disorder, Major"
      ],
      "interventions": [
        {
          "name": "GSK561679",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 64 Years · Female only"
      },
      "enrollment_count": 150,
      "start_date": "2008-10-02",
      "completion_date": "2010-06-18",
      "has_results": true,
      "last_update_posted_date": "2017-11-17",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 18,
      "location_summary": "Cerritos, California • San Diego, California • Torrance, California + 15 more",
      "locations": [
        {
          "city": "Cerritos",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00733980"
    },
    {
      "nct_id": "NCT06938542",
      "title": "Palliative Care Needs of Children With Rare Diseases and Their Families",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Trisomy 13 Syndrome",
        "Arthrogryposis Congenita Multiplex With Intestinal Atresia",
        "Asparagine Synthetase Deficiency",
        "CHARGE Syndrome",
        "Early Infantile Epileptic Encephalopathy",
        "FOXG1 Syndrome",
        "KBG Syndrome",
        "Noonan Syndrome",
        "Severe Hemophilia A",
        "Short Bowel Syndrome",
        "Beta-Propeller Protein-Associated Neurodegeneration",
        "Brain Injury of Prematurity With Periventricular Leukomalacia",
        "Chromosome 17p13.3 Microdeletion Syndrome",
        "Chromosome 1q43-1q44 Deletion",
        "Cockayne Syndrome",
        "Congenital Diaphragmatic Hernia",
        "End-Stage Renal Disease With Cloacal Anomaly",
        "Mitochondrial Depletion Disorder",
        "Severe Factor VII Deficiency"
      ],
      "interventions": [
        {
          "name": "Family Centered pediatric palliative care for family caregivers of children with rare diseases.",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "12 Months to 99 Years"
      },
      "enrollment_count": 480,
      "start_date": "2025-10-02",
      "completion_date": "2029-08-02",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-10-16T04:20:14.733Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06938542"
    }
  ]
}