{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+depression&page=98",
    "query": {
      "intervention": "Treatment of depression",
      "page": 98
    },
    "page_size": 10
  },
  "pagination": {
    "page": 98,
    "page_size": 10,
    "total_count": 3107,
    "total_pages": 311,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+depression&page=99&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Treatment+of+depression&page=97&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-05T22:01:15.250Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06043401",
      "title": "Tracking Brain Biomarkers and Renormalization Associated With Antidepressant Transcranial Magnetic Stimulation Therapy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Neuroimaging with Magnetic Resonance Imaging (MRI)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-04-04",
      "completion_date": "2027-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06043401"
    },
    {
      "nct_id": "NCT01369030",
      "title": "Deplin® P.L.U.S. Program (Progress Through Learning Understanding & Support)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Deplin®",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Pamlab, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 554,
      "start_date": "2010-11",
      "completion_date": "2012-04",
      "has_results": true,
      "last_update_posted_date": "2014-06-03",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 2,
      "location_summary": "Greensboro, North Carolina • Nashville, Tennessee",
      "locations": [
        {
          "city": "Greensboro",
          "state": "North Carolina"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01369030"
    },
    {
      "nct_id": "NCT01743339",
      "title": "Managing Sleep Symptoms and Modifying Mechanisms of Traumatic Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Disorders, Post-Traumatic",
        "Depression",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 110,
      "start_date": "2013-01",
      "completion_date": "2017-02",
      "has_results": false,
      "last_update_posted_date": "2017-04-27",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01743339"
    },
    {
      "nct_id": "NCT03302312",
      "title": "Effectiveness and Acceptability of Stellate Ganglion Block for Posttraumatic Stress Disorder Symptoms - Acceptability",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Posttraumatic Stress Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "RTI International",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2017-11-03",
      "completion_date": "2018-03-02",
      "has_results": false,
      "last_update_posted_date": "2018-07-30",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 2,
      "location_summary": "Honolulu, Hawaii • Fort Bragg, North Carolina",
      "locations": [
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Fort Bragg",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03302312"
    },
    {
      "nct_id": "NCT06057012",
      "title": "A Study of BRII-296 in Adults With Severe Postpartum Depression (PPD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Severe Postpartum Depression"
      ],
      "interventions": [
        {
          "name": "BRII-296",
          "type": "DRUG"
        },
        {
          "name": "Depo Medrol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brii Biosciences Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 11,
      "start_date": "2023-09-29",
      "completion_date": "2024-03-13",
      "has_results": false,
      "last_update_posted_date": "2025-01-27",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 11,
      "location_summary": "Sherman Oaks, California • Torrance, California • Boynton Beach, Florida + 7 more",
      "locations": [
        {
          "city": "Sherman Oaks",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Boynton Beach",
          "state": "Florida"
        },
        {
          "city": "Davie",
          "state": "Florida"
        },
        {
          "city": "Miami Springs",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06057012"
    },
    {
      "nct_id": "NCT01126346",
      "title": "Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Advanced Malignant Mesothelioma",
        "Carcinoma of the Appendix",
        "Ovarian Sarcoma",
        "Ovarian Stromal Cancer",
        "Pseudomyxoma Peritonei",
        "Recurrent Colon Cancer",
        "Recurrent Malignant Mesothelioma",
        "Recurrent Ovarian Epithelial Cancer",
        "Recurrent Ovarian Germ Cell Tumor",
        "Stage III Colon Cancer",
        "Stage III Ovarian Epithelial Cancer",
        "Stage III Ovarian Germ Cell Tumor",
        "Stage IV Colon Cancer",
        "Stage IV Ovarian Epithelial Cancer",
        "Stage IV Ovarian Germ Cell Tumor",
        "Unspecified Childhood Solid Tumor, Protocol Specific"
      ],
      "interventions": [
        {
          "name": "HIPEC Orientation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Consultation with Survivorship Navigator",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Questionnaires",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 10,
      "start_date": "2010-05",
      "completion_date": "2013-10",
      "has_results": false,
      "last_update_posted_date": "2018-07-03",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01126346"
    },
    {
      "nct_id": "NCT03687970",
      "title": "A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chemotherapy-induced Peripheral Neuropathy"
      ],
      "interventions": [
        {
          "name": "Brief Pain Inventory",
          "type": "OTHER"
        },
        {
          "name": "Hospital Anxiety and Depression Scale",
          "type": "OTHER"
        },
        {
          "name": "Neuropathic Pain Symptom Inventory",
          "type": "OTHER"
        },
        {
          "name": "Diode Laser fiber type Selective Stimulator",
          "type": "PROCEDURE"
        },
        {
          "name": "Quantitative sensory testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Conditioned pain modulation efficiency",
          "type": "PROCEDURE"
        },
        {
          "name": "Spontaneous pain at baseline on 0-10 Numerical Rating Scale (NRS)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2018-09-17",
      "completion_date": "2019-09-17",
      "has_results": true,
      "last_update_posted_date": "2021-05-19",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03687970"
    },
    {
      "nct_id": "NCT00070941",
      "title": "SAM-e for the Treatment of Depression in Patients With Parkinson's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Parkinson's Disease",
        "Depression"
      ],
      "interventions": [
        {
          "name": "SAM-e",
          "type": "DRUG"
        },
        {
          "name": "oral escitalopram",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "30 Years to 80 Years"
      },
      "enrollment_count": 29,
      "start_date": "2003-07",
      "completion_date": "2010-10",
      "has_results": true,
      "last_update_posted_date": "2016-07-13",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00070941"
    },
    {
      "nct_id": "NCT05567640",
      "title": "Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety Disorders and Symptoms",
        "Depressive Symptoms"
      ],
      "interventions": [
        {
          "name": "The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Space for depression",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Space for resilience",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston University Charles River Campus",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1800,
      "start_date": "2023-04-12",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-07-31",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05567640"
    },
    {
      "nct_id": "NCT03170908",
      "title": "Effective Implementation of Interpersonal Psychotherapy",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depressive Symptoms"
      ],
      "interventions": [
        {
          "name": "Interpersonal Psychotherapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 13,
      "start_date": "2017-05-19",
      "completion_date": "2019-12-06",
      "has_results": false,
      "last_update_posted_date": "2022-06-09",
      "last_synced_at": "2026-11-05T22:01:15.250Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03170908"
    }
  ]
}