{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trier+social+stress+test",
    "query": {
      "intervention": "Trier social stress test"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 40,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trier+social+stress+test&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T22:17:18.061Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07138443",
      "title": "Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress",
        "Mental Stress"
      ],
      "interventions": [
        {
          "name": "Melatonin 3 MG Oral Tablet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Oral Tablet",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Baylor University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 16,
      "start_date": "2025-08-01",
      "completion_date": "2026-07-20",
      "has_results": false,
      "last_update_posted_date": "2026-07-21",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 1,
      "location_summary": "Waco, Texas",
      "locations": [
        {
          "city": "Waco",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07138443"
    },
    {
      "nct_id": "NCT06091189",
      "title": "Internalized Stress in Relation to Alcohol Consumption",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Stress, Physiological",
        "Ethanol Intoxication",
        "Distress, Emotional"
      ],
      "interventions": [
        {
          "name": "Relevant Trier Social Stressor Test (TSST)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Ethanol",
          "type": "DRUG"
        },
        {
          "name": "Placebo Trier Social Stressor Test (TSST)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Placebo Beverage",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Irrelevant Trier Social Stressor Test (TSST)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Texas Tech University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "21 Years to 29 Years"
      },
      "enrollment_count": 165,
      "start_date": "2024-02-12",
      "completion_date": "2025-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-05-08",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06091189"
    },
    {
      "nct_id": "NCT06977178",
      "title": "Adverse Adolescent Pathways to Substance Use",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Adolescent Development",
        "Substance Use"
      ],
      "interventions": [
        {
          "name": "Trier Social Stress Test",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "12 Years to 14 Years"
      },
      "enrollment_count": 180,
      "start_date": "2024-02-20",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-05-18",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06977178"
    },
    {
      "nct_id": "NCT07244809",
      "title": "Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adverse Childhood Experience",
        "Endothelial Function (FMD)",
        "Endothelial Injury",
        "Mitochondrial Function",
        "Oxidative Stress",
        "Psychosocial Influence on Cardiovascular Disease"
      ],
      "interventions": [
        {
          "name": "Mitoquinone mesylate (MitoQ)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "18 Years to 29 Years"
      },
      "enrollment_count": 300,
      "start_date": "2025-10-13",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-24",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07244809"
    },
    {
      "nct_id": "NCT03467997",
      "title": "Mental Stress & Diesel Exhaust on Cardiovascular Health",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blood Pressure",
        "Inflammation",
        "Catecholamines"
      ],
      "interventions": [
        {
          "name": "Trier social stress test",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Diesel exhaust",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "22 Years to 49 Years"
      },
      "enrollment_count": 22,
      "start_date": "2018-03-22",
      "completion_date": "2020-01",
      "has_results": false,
      "last_update_posted_date": "2018-11-05",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03467997"
    },
    {
      "nct_id": "NCT03450135",
      "title": "Neurophysiology, Estrogen, and Stress Exposure in the Emergence of Depression in Adolescent Girls",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Adolescent Development",
        "Stress",
        "Emotional Disturbances"
      ],
      "interventions": [
        {
          "name": "Trier Social Stress Test",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Emotional go/no-go task",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "14 Years",
        "sex": "FEMALE",
        "summary": "11 Years to 14 Years · Female only"
      },
      "enrollment_count": 53,
      "start_date": "2018-02-25",
      "completion_date": "2020-06-30",
      "has_results": false,
      "last_update_posted_date": "2020-11-24",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03450135"
    },
    {
      "nct_id": "NCT04831424",
      "title": "Mitochondrial Stress, Brain Imaging, and Epigenetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mitochondrial Diseases"
      ],
      "interventions": [
        {
          "name": "Trier social stress test",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 110,
      "start_date": "2018-06-12",
      "completion_date": "2024-05-03",
      "has_results": true,
      "last_update_posted_date": "2025-05-20",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04831424"
    },
    {
      "nct_id": "NCT01363180",
      "title": "Stress-induced Drinking in Emerging Adults: the Role of Trauma History",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Trauma",
        "Posttraumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Trier Social Stress Test (TSST)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No stress condition",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "21 Years to 30 Years"
      },
      "enrollment_count": 197,
      "start_date": "2011-01-01",
      "completion_date": "2016-06-01",
      "has_results": false,
      "last_update_posted_date": "2018-06-18",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01363180"
    },
    {
      "nct_id": "NCT04174651",
      "title": "Stress-induced Scratching in Healthy and AD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy",
        "Atopic Dermatitis"
      ],
      "interventions": [
        {
          "name": "Trier Social Stress Test (TSST)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Landscape Video",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "59 Years",
        "sex": "ALL",
        "summary": "18 Years to 59 Years"
      },
      "enrollment_count": 8,
      "start_date": "2020-01-27",
      "completion_date": "2022-07-19",
      "has_results": false,
      "last_update_posted_date": "2022-08-10",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04174651"
    },
    {
      "nct_id": "NCT02725385",
      "title": "Stress and Coping in Caregivers of Younger Patients With Cancer",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anxiety",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Physiologic Testing",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 163,
      "start_date": "2014-03",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2018-07-02",
      "last_synced_at": "2026-09-28T22:17:18.061Z",
      "location_count": 2,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02725385"
    }
  ]
}