{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trimethoprim%2FSulfamethoxazole+%28TMP%2FSMX%29&page=3", "query": { "intervention": "Trimethoprim/Sulfamethoxazole (TMP/SMX)", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 130, "total_pages": 13, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trimethoprim%2FSulfamethoxazole+%28TMP%2FSMX%29&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trimethoprim%2FSulfamethoxazole+%28TMP%2FSMX%29&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-09T16:18:02.968Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05488340", "title": "A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Urinary Tract Infections" ], "interventions": [ { "name": "LBP-EC01 0.1 x IV dose", "type": "DRUG" }, { "name": "LBP-EC01 0.01x IV Dose", "type": "DRUG" }, { "name": "LBP-EC01 IV Infusion Dose", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "LBP-EC01", "type": "DRUG" }, { "name": "TMP/SMX", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Locus Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "FEMALE", "summary": "18 Years to 75 Years · Female only" }, "enrollment_count": 318, "start_date": "2022-07-13", "completion_date": "2027-12", "has_results": false, "last_update_posted_date": "2026-09-14", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 17, "location_summary": "Fresno, California • Lancaster, California • Los Angeles, California + 13 more", "locations": [ { "city": "Fresno", "state": "California" }, { "city": "Lancaster", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Montebello", "state": "California" }, { "city": "Murrieta", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05488340" }, { "nct_id": "NCT02853604", "title": "Study of ADXS11-001 in Participants With High Risk Locally Advanced Cervical Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "High Risk Cervical Cancer", "Advanced Cervical Cancer" ], "interventions": [ { "name": "ADXS11-001", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Advaxis, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 110, "start_date": "2015-12-15", "completion_date": "2019-07-31", "has_results": true, "last_update_posted_date": "2023-03-14", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 41, "location_summary": "Mobile, Alabama • Phoenix, Arizona • Duarte, California + 35 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Duarte", "state": "California" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02853604" }, { "nct_id": "NCT02375295", "title": "Struvite Stones Antibiotic Study", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Kidney Stones" ], "interventions": [ { "name": "ciprofloxacin, cotrimoxazole-trimethoprim, macrodantin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of British Columbia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 28, "start_date": "2015-03", "completion_date": "2023-12", "has_results": false, "last_update_posted_date": "2022-05-17", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 11, "location_summary": "Scottsdale, Arizona • San Diego, California • Baltimore, Maryland + 8 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "San Diego", "state": "California" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02375295" }, { "nct_id": "NCT01049633", "title": "B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure", "overall_status": "NO_LONGER_AVAILABLE", "study_type": "EXPANDED_ACCESS", "phases": [], "conditions": [ "Type 1 Diabetes Mellitus" ], "interventions": [ { "name": "Allogeneic Pancreatic Islet Cells", "type": "BIOLOGICAL" }, { "name": "Sirolimus", "type": "DRUG" }, { "name": "Basiliximab", "type": "BIOLOGICAL" }, { "name": "Tacrolimus", "type": "DRUG" }, { "name": "Antibacterial, Antifungal, and Antiviral Prophylaxis", "type": "DRUG" }, { "name": "Trimethoprim/sulfamethoxazole", "type": "DRUG" }, { "name": "Clotrimazole", "type": "DRUG" }, { "name": "Valganciclovir", "type": "DRUG" }, { "name": "Heparin", "type": "DRUG" }, { "name": "Enoxaparin", "type": "DRUG" }, { "name": "Pentoxifylline", "type": "DRUG" }, { "name": "Aspirin", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": null, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2014-06-11", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01049633" }, { "nct_id": "NCT01599806", "title": "Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis" ], "interventions": [ { "name": "Ceftazidime - Avibactam ( CAZ-AVI)", "type": "DRUG" }, { "name": "Doripenem", "type": "DRUG" }, { "name": "Either switch to oral therapy: 500 mg of Ciprofloxacin (oral)", "type": "DRUG" }, { "name": "or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 641, "start_date": "2012-10", "completion_date": "2014-08", "has_results": true, "last_update_posted_date": "2017-09-06", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 3, "location_summary": "Detroit, Michigan • St Louis, Missouri • Indiana, Pennsylvania", "locations": [ { "city": "Detroit", "state": "Michigan" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Indiana", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01599806" }, { "nct_id": "NCT00023244", "title": "Steroid Withdrawal in Pediatric Kidney Transplant Recipients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "End-Stage Renal Disease" ], "interventions": [ { "name": "Basiliximab", "type": "DRUG" }, { "name": "Cyclosporine", "type": "DRUG" }, { "name": "Tacrolimus", "type": "DRUG" }, { "name": "Sirolimus", "type": "DRUG" }, { "name": "Methylprednisolone", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Bactrim", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "20 Years", "sex": "ALL", "summary": "1 Day to 20 Years" }, "enrollment_count": 274, "start_date": "2001-01", "completion_date": "2005-06", "has_results": false, "last_update_posted_date": "2016-10-21", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 18, "location_summary": "Birmingham, Alabama • San Diego, California • Aurora, Colorado + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "San Diego", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00023244" }, { "nct_id": "NCT01595438", "title": "Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis" ], "interventions": [ { "name": "Ceftazidime - Avibactam ( CAZ-AVI)", "type": "DRUG" }, { "name": "Doripenem", "type": "DRUG" }, { "name": "Either switch to oral therapy: 500 mg of Ciprofloxacin (oral)", "type": "DRUG" }, { "name": "or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 598, "start_date": "2012-10", "completion_date": "2014-08", "has_results": true, "last_update_posted_date": "2017-09-06", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 3, "location_summary": "Sylmar, California • Royal Oak, Michigan • Lima, Ohio", "locations": [ { "city": "Sylmar", "state": "California" }, { "city": "Royal Oak", "state": "Michigan" }, { "city": "Lima", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01595438" }, { "nct_id": "NCT02128087", "title": "Improving Drug Adherence Among Adolescents in Uganda Using SMS Reminders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Human Immunodeficiency Virus" ], "interventions": [ { "name": "Two-way SMS intervention", "type": "BEHAVIORAL" }, { "name": "One-way SMS intervention group", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "RAND", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": "24 Years", "sex": "ALL", "summary": "15 Years to 24 Years" }, "enrollment_count": 330, "start_date": "2013-02", "completion_date": "2017-03-31", "has_results": false, "last_update_posted_date": "2017-04-14", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 1, "location_summary": "Santa Monica, California", "locations": [ { "city": "Santa Monica", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02128087" }, { "nct_id": "NCT00000655", "title": "A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pneumonia, Pneumocystis Carinii", "HIV Infections" ], "interventions": [ { "name": "Atovaquone", "type": "DRUG" }, { "name": "Sulfamethoxazole-Trimethoprim", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 300, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2011-03-01", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 27, "location_summary": "Birmingham, Alabama • Harbor City, California • Los Angeles, California + 15 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Harbor City", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000655" }, { "nct_id": "NCT00973765", "title": "Prospective Randomized Trial of Bactrim on 7 Day Outcome in Patients With Uncomplicated Abscesses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Abscesses" ], "interventions": [ { "name": "bactrim", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "59th Medical Wing", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": 212, "start_date": "2007-11", "completion_date": "2009-08", "has_results": true, "last_update_posted_date": "2010-03-09", "last_synced_at": "2026-10-09T16:18:02.968Z", "location_count": 1, "location_summary": "Lackland Air Force Base, Texas", "locations": [ { "city": "Lackland Air Force Base", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00973765" } ] }