{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Trimethoprim%2Fsulfamethoxazole+%28TMP%2FSMZ%29",
    "query": {
      "intervention": "Trimethoprim/sulfamethoxazole (TMP/SMZ)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-01T23:49:55.539Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04502095",
      "title": "Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Bladder Carcinoma",
        "Refractory Bladder Carcinoma",
        "Urinary Tract Infection"
      ],
      "interventions": [
        {
          "name": "Clindamycin",
          "type": "DRUG"
        },
        {
          "name": "Diary",
          "type": "OTHER"
        },
        {
          "name": "Ertapenem",
          "type": "DRUG"
        },
        {
          "name": "Levofloxacin",
          "type": "DRUG"
        },
        {
          "name": "Nitrofurantoin",
          "type": "DRUG"
        },
        {
          "name": "Trimethoprim-Sulfamethoxazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Roswell Park Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 89,
      "start_date": "2020-09-02",
      "completion_date": "2025-03-13",
      "has_results": false,
      "last_update_posted_date": "2025-08-03",
      "last_synced_at": "2026-09-01T23:49:55.539Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04502095"
    },
    {
      "nct_id": "NCT00789464",
      "title": "Probiotics for Girls With Recurring Urinary Tract Infections",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Recurrent Urinary Tract Infection"
      ],
      "interventions": [
        {
          "name": "Lactobacillus reuteri DSM 17938",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "trimethoprim/sulfamethoxazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "17 Years",
        "sex": "FEMALE",
        "summary": "3 Months to 17 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2020-08-18",
      "last_synced_at": "2026-09-01T23:49:55.539Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00789464"
    },
    {
      "nct_id": "NCT01631617",
      "title": "Effects of Treatments on Atopic Dermatitis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Eczema",
        "Dermatitis",
        "Skin Diseases, Genetic",
        "Dermatitis, Atopic",
        "Skin Diseases"
      ],
      "interventions": [
        {
          "name": "Trimethoprim/sulfamethoxazole (TMP/SMZ)",
          "type": "DRUG"
        },
        {
          "name": "Cephalexin",
          "type": "DRUG"
        },
        {
          "name": "Doxycycline",
          "type": "DRUG"
        },
        {
          "name": "Sodium hypochlorite",
          "type": "OTHER"
        },
        {
          "name": "Placebo capsules",
          "type": "OTHER"
        },
        {
          "name": "Placebo Sodium hypochlorite",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "2 Years to 50 Years"
      },
      "enrollment_count": 130,
      "start_date": "2012-09-18",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-09-01T23:49:55.539Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01631617"
    }
  ]
}