{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tropicamide", "query": { "intervention": "Tropicamide" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 15, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tropicamide&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T05:33:41.841Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03959176", "title": "The Effect of Brimonidine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Intraocular Pressure" ], "interventions": [ { "name": "Brimonidine", "type": "DRUG" }, { "name": "Tropicamide", "type": "DRUG" }, { "name": "Phenylephrine Ophthalmic Product", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 13, "start_date": "2019-07-20", "completion_date": "2019-07-20", "has_results": true, "last_update_posted_date": "2024-02-01", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03959176" }, { "nct_id": "NCT02373137", "title": "Descemet Endothelial Thickness Comparison Trial", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Keratoplasty", "Grafting, Corneal", "Transplantation, Corneal", "Transplantation, Cornea", "Keratoplasty, Lamellar" ], "interventions": [ { "name": "DSAEK", "type": "PROCEDURE" }, { "name": "DMEK", "type": "PROCEDURE" }, { "name": "Endoserter", "type": "DEVICE" }, { "name": "Prednisolone", "type": "DRUG" }, { "name": "Ofloxacin", "type": "DRUG" }, { "name": "Tropicamide", "type": "DRUG" }, { "name": "Phenylephrine", "type": "DRUG" }, { "name": "Jones Tube", "type": "DEVICE" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "DRUG" ], "sponsor": "Oregon Health and Science University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 38, "start_date": "2015-01-22", "completion_date": "2023-05-30", "has_results": true, "last_update_posted_date": "2020-11-25", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 3, "location_summary": "Palo Alto, California • San Francisco, California • Portland, Oregon", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT02373137" }, { "nct_id": "NCT00748059", "title": "The Pathophysiology of Orthostatic Hypotension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Autonomic Nervous System Diseases", "Orthostatic Hypotension", "Dopamine Beta-Hydroxylase Deficiency", "Orthostatic Intolerance" ], "interventions": [ { "name": "Standing or upright tilt", "type": "PROCEDURE" }, { "name": "Microneurography", "type": "PROCEDURE" }, { "name": "QSweat", "type": "PROCEDURE" }, { "name": "neck cuff stimulation", "type": "DEVICE" }, { "name": "phenylephrine,isoproterenol,nitroprusside,propranolol,edrophonium,atropine,tyramine", "type": "DRUG" }, { "name": "clonidine,yohimbine,metoclopramide,alpha-methyldopa", "type": "DRUG" }, { "name": "BodPod", "type": "PROCEDURE" }, { "name": "Eye exam", "type": "PROCEDURE" }, { "name": "Sleep study", "type": "PROCEDURE" }, { "name": "Pain response testing", "type": "PROCEDURE" }, { "name": "Metabolic chamber", "type": "PROCEDURE" }, { "name": "Brain function studies", "type": "PROCEDURE" }, { "name": "Bicycle Exercise Test", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "12 Years to 70 Years" }, "enrollment_count": 10, "start_date": "1996-12", "completion_date": "2020-12", "has_results": false, "last_update_posted_date": "2021-05-12", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00748059" }, { "nct_id": "NCT06366217", "title": "Efficacy of the MydCombi on Pupillary Dilation in Pediatric and Adult Patients", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Dilation", "Pupil Reaction Absent" ], "interventions": [ { "name": "MydCombi Device", "type": "DEVICE" }, { "name": "MydCombi Drug", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": null, "sex": "ALL", "summary": "2 Years and older" }, "enrollment_count": 100, "start_date": "2024-09-30", "completion_date": "2024-12-31", "has_results": false, "last_update_posted_date": "2024-09-19", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06366217" }, { "nct_id": "NCT03139708", "title": "The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Intraocular Pressure" ], "interventions": [ { "name": "Alphagan", "type": "DRUG" }, { "name": "Phenylephrine", "type": "DRUG" }, { "name": "Tropicamide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 5, "start_date": "2016-09", "completion_date": "2017-10", "has_results": false, "last_update_posted_date": "2018-08-09", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03139708" }, { "nct_id": "NCT00227253", "title": "Chromosome 18 Clinical Research Center", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Chromosome Aberrations", "Growth Hormone Deficiency", "Hypomyelination" ], "interventions": [ { "name": "Determination of growth hormone status", "type": "PROCEDURE" }, { "name": "Measurement of growth, thyroid and sex hormone levels", "type": "PROCEDURE" }, { "name": "Behavior and neuropsychometric evaluations", "type": "PROCEDURE" }, { "name": "Audiological and ear, nose and throat examination", "type": "PROCEDURE" }, { "name": "Magnetic resonance imaging of the brain", "type": "PROCEDURE" }, { "name": "Dysmorphology evaluation", "type": "PROCEDURE" }, { "name": "Neurology examination", "type": "PROCEDURE" }, { "name": "Dental evaluation", "type": "PROCEDURE" }, { "name": "Speech pathology evaluation", "type": "PROCEDURE" }, { "name": "Psychiatric evaluation", "type": "PROCEDURE" }, { "name": "Orthopedic evaluation", "type": "PROCEDURE" }, { "name": "Ophthalmologic evaluation", "type": "PROCEDURE" }, { "name": "Gastrointestinal evaluation", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 4000, "start_date": "1993-09", "completion_date": "2040-12", "has_results": false, "last_update_posted_date": "2026-01-06", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 2, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00227253" }, { "nct_id": "NCT05238233", "title": "Wearing-Off Period of Pharmacological Dilation and Anisocoria", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anisocoria" ], "interventions": [ { "name": "Tropicamide", "type": "DRUG" }, { "name": "1% Pilocarpine", "type": "DRUG" }, { "name": "Proparacaine Hydrochloride", "type": "DRUG" }, { "name": "Tono pen AVIA", "type": "DEVICE" }, { "name": "VG4 Gonio", "type": "DEVICE" }, { "name": "Reichert phoropter", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Prisma Health-Upstate", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 11, "start_date": "2022-04-01", "completion_date": "2023-01-17", "has_results": true, "last_update_posted_date": "2023-03-07", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 1, "location_summary": "Greenville, South Carolina", "locations": [ { "city": "Greenville", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05238233" }, { "nct_id": "NCT03751631", "title": "Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Mydriasis" ], "interventions": [ { "name": "Tropicamide 1%-Phenylephrine 2.5% ophthalmic solution (TR/PE)", "type": "DRUG" }, { "name": "Tropicamide 1% ophthalmic solution (TR)", "type": "DRUG" }, { "name": "Phenylephrine 2.5% ophthalmic solution (PE)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eyenovia Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 70, "start_date": "2018-11-15", "completion_date": "2019-01-11", "has_results": true, "last_update_posted_date": "2022-03-18", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 1, "location_summary": "Cypress, California", "locations": [ { "city": "Cypress", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03751631" }, { "nct_id": "NCT03201562", "title": "A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Presbyopia" ], "interventions": [ { "name": "Aceclidine+tropicamide combination", "type": "DRUG" }, { "name": "Aceclidine", "type": "DRUG" }, { "name": "Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "LENZ Therapeutics, Inc", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "48 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "48 Years to 64 Years" }, "enrollment_count": 58, "start_date": "2017-04-30", "completion_date": "2018-05-20", "has_results": true, "last_update_posted_date": "2022-09-22", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 1, "location_summary": "Andover, Massachusetts", "locations": [ { "city": "Andover", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03201562" }, { "nct_id": "NCT03751098", "title": "Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Mydriasis" ], "interventions": [ { "name": "Tropicamide/Phenylephrine ophthalmic solution (TR/PE)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eyenovia Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 76, "start_date": "2018-12-01", "completion_date": "2019-01-21", "has_results": true, "last_update_posted_date": "2022-03-18", "last_synced_at": "2026-09-02T05:33:41.841Z", "location_count": 2, "location_summary": "Austin, Texas • San Antonio, Texas", "locations": [ { "city": "Austin", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03751098" } ] }