{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Unified+Protocol+for+Adolescents+%28UP-A%29",
    "query": {
      "intervention": "Unified Protocol for Adolescents (UP-A)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T22:33:34.317Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04365543",
      "title": "Treatment for Youth (Ages 8 to 16 Years Old) With Misophonia (U-HEAR)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Misophonia"
      ],
      "interventions": [
        {
          "name": "Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents (UP-C/A) for youth with misophonia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychoeducation and Relaxation Therapy (PRT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "8 Years to 16 Years"
      },
      "enrollment_count": 124,
      "start_date": "2020-04-08",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2020-04-28",
      "last_synced_at": "2026-09-30T22:33:34.317Z",
      "location_count": 2,
      "location_summary": "Coral Gables, Florida • St. Petersburg, Florida",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04365543"
    },
    {
      "nct_id": "NCT03315208",
      "title": "Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Use Disorders",
        "Depression",
        "Anxiety",
        "Emotional Disorder",
        "Suicidal Ideation",
        "Suicidal and Self-injurious Behavior"
      ],
      "interventions": [
        {
          "name": "Unified Protocol (UP)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Treatment as Usual (TAU)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "26 Years",
        "sex": "ALL",
        "summary": "18 Years to 26 Years"
      },
      "enrollment_count": 56,
      "start_date": "2017-11-22",
      "completion_date": "2019-09-20",
      "has_results": true,
      "last_update_posted_date": "2021-04-01",
      "last_synced_at": "2026-09-30T22:33:34.317Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03315208"
    },
    {
      "nct_id": "NCT07483333",
      "title": "Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Trauma Exposure",
        "Trauma",
        "Trauma and Stressor Related Disorder",
        "Mental Health Functioning",
        "Chronic Medical Conditions",
        "Chronic Medical Condition",
        "Chronic Medical Illness",
        "Posttraumatic Stress Disorder PTSD",
        "Posttraumatic Stress Disorders",
        "Posttraumatic Stress Symptoms",
        "Posttraumatic Stress"
      ],
      "interventions": [
        {
          "name": "Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Structured Psychotherapy for Adolescents Responding to Chronic Stress - Individual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Anthony Vesco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "8 Years to 18 Years"
      },
      "enrollment_count": 400,
      "start_date": "2026-10",
      "completion_date": "2029-09-29",
      "has_results": false,
      "last_update_posted_date": "2026-09-15",
      "last_synced_at": "2026-09-30T22:33:34.317Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07483333"
    },
    {
      "nct_id": "NCT03102008",
      "title": "Unified Protocol for Adolescents (UP-A) Change Processes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety Disorders",
        "Depression",
        "Obsessive-Compulsive Disorder",
        "Adolescent - Emotional Problem",
        "Emotional Disorder"
      ],
      "interventions": [
        {
          "name": "Unified Protocol for Emotional Disorders in Adolescents (UP-A)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 9,
      "start_date": "2017-01-12",
      "completion_date": "2017-12-14",
      "has_results": false,
      "last_update_posted_date": "2018-11-27",
      "last_synced_at": "2026-09-30T22:33:34.317Z",
      "location_count": 1,
      "location_summary": "Coral Gables, Florida",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03102008"
    },
    {
      "nct_id": "NCT06158581",
      "title": "Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorder"
      ],
      "interventions": [
        {
          "name": "The Emotion Awareness and Skills Enhancement Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The Unified Protocol",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "10 Years to 30 Years"
      },
      "enrollment_count": 470,
      "start_date": "2024-04-08",
      "completion_date": "2027-08-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-09-30T22:33:34.317Z",
      "location_count": 2,
      "location_summary": "Tuscaloosa, Alabama • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Tuscaloosa",
          "state": "Alabama"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06158581"
    },
    {
      "nct_id": "NCT04792151",
      "title": "Youth PHP Pilot Transdiagnostic Treatment Implementation and Effectiveness Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Emotional Disorder"
      ],
      "interventions": [
        {
          "name": "Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "6 Years to 85 Years"
      },
      "enrollment_count": 304,
      "start_date": "2021-04-15",
      "completion_date": "2022-04-25",
      "has_results": false,
      "last_update_posted_date": "2022-08-19",
      "last_synced_at": "2026-09-30T22:33:34.317Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04792151"
    },
    {
      "nct_id": "NCT02567266",
      "title": "Community Study of Outcome Monitoring for Emotional Disorders in Teens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Unified Protocol for Adolescents (UP-A)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Youth Outcomes Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Treatment as Usual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 196,
      "start_date": "2016-01",
      "completion_date": "2020-07-30",
      "has_results": true,
      "last_update_posted_date": "2021-08-18",
      "last_synced_at": "2026-09-30T22:33:34.317Z",
      "location_count": 2,
      "location_summary": "West Hartford, Connecticut • Coral Gables, Florida",
      "locations": [
        {
          "city": "West Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02567266"
    },
    {
      "nct_id": "NCT06038721",
      "title": "Unified Protocol: Community Connections",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mental Health Issue",
        "Anxiety Disorder",
        "Depressive Disorder",
        "Parenting"
      ],
      "interventions": [
        {
          "name": "The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Children",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Adolescents",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 1500,
      "start_date": "2023-09-25",
      "completion_date": "2028-09-25",
      "has_results": false,
      "last_update_posted_date": "2026-09-21",
      "last_synced_at": "2026-09-30T22:33:34.317Z",
      "location_count": 1,
      "location_summary": "Coral Gables, Florida",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06038721"
    },
    {
      "nct_id": "NCT00628888",
      "title": "A Waitlist-Controlled Trial of the Unified Protocol for the Treatment of Emotional Disorders in Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety Disorders",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Unified Protocol for Adolescents (UP-A)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 51,
      "start_date": "2006-07",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2014-12-19",
      "last_synced_at": "2026-09-30T22:33:34.317Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00628888"
    }
  ]
}