{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Unrestricted",
    "query": {
      "intervention": "Unrestricted"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 59,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Unrestricted&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T09:54:29.209Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04840095",
      "title": "Dynamic Connectivity Under Metabolic Constraints",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Insulin Resistance",
        "Healthy",
        "Diet Modification",
        "Aging"
      ],
      "interventions": [
        {
          "name": "Ketones",
          "type": "DRUG"
        },
        {
          "name": "Glucose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 80,
      "start_date": "2015-06-19",
      "completion_date": "2023-09",
      "has_results": false,
      "last_update_posted_date": "2023-01-12",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 2,
      "location_summary": "Charlestown, Massachusetts • Stony Brook, New York",
      "locations": [
        {
          "city": "Charlestown",
          "state": "Massachusetts"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04840095"
    },
    {
      "nct_id": "NCT06568900",
      "title": "Randomized Controlled Trial to Evaluate the Impact of ZYN Nicotine Pouch Products on Cigarette Usage and BoExp in Adult Smokers Over a 12-week Period",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "cigarette smoking",
          "type": "OTHER"
        },
        {
          "name": "tobacco flavored and unflavored pouch",
          "type": "OTHER"
        },
        {
          "name": "unrestricted flavor options pouch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Swedish Match AB",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 450,
      "start_date": "2023-07-31",
      "completion_date": "2024-08-19",
      "has_results": false,
      "last_update_posted_date": "2024-08-23",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 1,
      "location_summary": "Raleigh, North Carolina",
      "locations": [
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06568900"
    },
    {
      "nct_id": "NCT06672042",
      "title": "Parental Adherence of a Mobile Application",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pediatrics",
        "Medically Complex",
        "Children With Medical Complexity (CMC)",
        "Nursing"
      ],
      "interventions": [
        {
          "name": "CHAMP App",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "0 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2025-08",
      "completion_date": "2028-08",
      "has_results": false,
      "last_update_posted_date": "2025-04-10",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06672042"
    },
    {
      "nct_id": "NCT03792451",
      "title": "Nutrition Status of Adults Treated With Pegvaliase",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Phenylketonurias"
      ],
      "interventions": [
        {
          "name": "Pegvaliase",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 18,
      "start_date": "2019-01-17",
      "completion_date": "2020-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-03-04",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03792451"
    },
    {
      "nct_id": "NCT03417648",
      "title": "A Nutrition Intervention for Arthritis -3 (WCCR-ARTH3)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "Plant-based diet",
          "type": "OTHER"
        },
        {
          "name": "Supplement",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Physicians Committee for Responsible Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 8,
      "start_date": "2018-03-08",
      "completion_date": "2018-12-14",
      "has_results": false,
      "last_update_posted_date": "2019-03-04",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03417648"
    },
    {
      "nct_id": "NCT03519360",
      "title": "Reducing Arrhythmia in Dialysis by Adjusting the Rx Electrolytes/Ultrafiltration, Study B",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "UFR-restricted dialysis",
          "type": "OTHER"
        },
        {
          "name": "UFR-unrestricted dialysis",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-07-01",
      "completion_date": "2021-02-01",
      "has_results": false,
      "last_update_posted_date": "2021-07-22",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03519360"
    },
    {
      "nct_id": "NCT04221269",
      "title": "Suicide Prevention Intervention for Schizophrenia-Spectrum Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Schizophrenia",
        "Suicide"
      ],
      "interventions": [
        {
          "name": "Enhanced Treatment as Usual",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Coping Long-term with Active Suicide Program for Schizophrenia",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Butler Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2020-12-01",
      "completion_date": "2023-06-01",
      "has_results": false,
      "last_update_posted_date": "2023-07-11",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04221269"
    },
    {
      "nct_id": "NCT02015390",
      "title": "Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Techniques for the Treatment of Large Long Bone Defects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Segmental Long Bone Defects"
      ],
      "interventions": [
        {
          "name": "Autogenous RIA bone grafting",
          "type": "PROCEDURE"
        },
        {
          "name": "Allogeneic bone grafting",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 16,
      "start_date": "2013-10-01",
      "completion_date": "2019-12-31",
      "has_results": true,
      "last_update_posted_date": "2021-06-28",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02015390"
    },
    {
      "nct_id": "NCT07475377",
      "title": "Understanding the Impact of Meal Timing on Neurological Health in Adults With Multiple Sclerosis",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Time Restricted Eating",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unrestricted eating",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 22,
      "start_date": "2026-08-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-13",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07475377"
    },
    {
      "nct_id": "NCT06736730",
      "title": "Mississippi Violence Injury Prevention (VIP) Program",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gun Shot Wound"
      ],
      "interventions": [
        {
          "name": "Hospital-Linked Violence Intervention Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mobile Community Event Support",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unrestricted Cash Assistance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Mississippi Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2025-03-01",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-01-16",
      "last_synced_at": "2026-09-04T09:54:29.209Z",
      "location_count": 1,
      "location_summary": "Jackson, Mississippi",
      "locations": [
        {
          "city": "Jackson",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06736730"
    }
  ]
}