{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Upper+Airway+Therapy",
    "query": {
      "intervention": "Upper Airway Therapy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 75,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Upper+Airway+Therapy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T04:09:49.165Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07577661",
      "title": "Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Sleep-disordered Breathing"
      ],
      "interventions": [
        {
          "name": "Combination device and drug: Unilateral hypoglossal nerve stimulation & atomoxetine-plus-oxybutynin (HGNS+AtoOxy)",
          "type": "OTHER"
        },
        {
          "name": "Unilateral hypoglossal nerve stimulation (HGNS), active comparator condition",
          "type": "DEVICE"
        },
        {
          "name": "Atomoxetine-plus-oxybutynin (80/5 mg) (AtoOxy), active comparator condition",
          "type": "DRUG"
        },
        {
          "name": "Placebo; placebo comparator condition",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 24,
      "start_date": "2026-09-01",
      "completion_date": "2028-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-21",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07577661"
    },
    {
      "nct_id": "NCT05350332",
      "title": "Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Negative Pressure Ventilator",
          "type": "DEVICE"
        },
        {
          "name": "Pulmonary Function Testing (PFT)",
          "type": "DEVICE"
        },
        {
          "name": "Transcutaneous Phrenic Nerve Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Percutaneous Phrenic Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 151,
      "start_date": "2022-06-30",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-08-26",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05350332"
    },
    {
      "nct_id": "NCT03664765",
      "title": "Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "OSA",
        "SCI/D",
        "Upper Airway Exercise"
      ],
      "interventions": [
        {
          "name": "UA and RMT",
          "type": "OTHER"
        },
        {
          "name": "Sham exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 29,
      "start_date": "2019-01-01",
      "completion_date": "2022-02-28",
      "has_results": true,
      "last_update_posted_date": "2024-03-12",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03664765"
    },
    {
      "nct_id": "NCT00252629",
      "title": "Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Apnea, Sleep",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Nasal CPAP treatment during sleep",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "32 Years",
        "maximum_age": "52 Years",
        "sex": "MALE",
        "summary": "32 Years to 52 Years · Male only"
      },
      "enrollment_count": 29,
      "start_date": "2005-11",
      "completion_date": "2010-11",
      "has_results": true,
      "last_update_posted_date": "2014-12-11",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 1,
      "location_summary": "Northport, New York",
      "locations": [
        {
          "city": "Northport",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00252629"
    },
    {
      "nct_id": "NCT06922955",
      "title": "A Prospective Study Comparing VivAer to Alternative Surgical Procedures to Treat Nasal Airway Obstruction in Patients With Nasal Valve Dysfunction.",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nasal Airway Obstruction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Aerin Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "22 Years to 85 Years"
      },
      "enrollment_count": 400,
      "start_date": "2025-02-28",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 35,
      "location_summary": "Alexander City, Alabama • Birmingham, Alabama • Huntsville, Alabama + 27 more",
      "locations": [
        {
          "city": "Alexander City",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Opelika",
          "state": "Alabama"
        },
        {
          "city": "Goodyear",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06922955"
    },
    {
      "nct_id": "NCT05154214",
      "title": "Surgical Treatment of Children With OSA and Small Tonsils or Down Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obstructive Sleep Apnea of Child"
      ],
      "interventions": [
        {
          "name": "Adenotonsillectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Drug-induced sleep endoscopy directed surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "2 Years to 18 Years"
      },
      "enrollment_count": 30,
      "start_date": "2021-11-09",
      "completion_date": "2024-10-11",
      "has_results": false,
      "last_update_posted_date": "2025-09-29",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05154214"
    },
    {
      "nct_id": "NCT00203996",
      "title": "Polycystic Ovary Syndrome (PCOS) and Sleep Apnea",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Polycystic Ovary Syndrome",
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "continuous positive airway pressure (CPAP)",
          "type": "DEVICE"
        },
        {
          "name": "depot leuprolide plus estrogen/progestin replacement",
          "type": "DRUG"
        },
        {
          "name": "pioglitazone",
          "type": "DRUG"
        },
        {
          "name": "REM frag",
          "type": "PROCEDURE"
        },
        {
          "name": "SWS supp",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 37,
      "start_date": "2003-09",
      "completion_date": "2008-06",
      "has_results": true,
      "last_update_posted_date": "2023-03-21",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00203996"
    },
    {
      "nct_id": "NCT05665244",
      "title": "Laryngeal Cryotherapy for Refractory Neurogenic Cough",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Upper-Airway Cough Syndrome"
      ],
      "interventions": [
        {
          "name": "Laryngeal cryotherapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Cryoprobe",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2022-12-26",
      "completion_date": "2027-02",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05665244"
    },
    {
      "nct_id": "NCT00435994",
      "title": "Assessment of Airway Obstruction in Infants With Lower Respiratory Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchiolitis",
        "Respiratory Syncytial Virus Infections"
      ],
      "interventions": [
        {
          "name": "Inhaled primatene will be given as a breathing treatment",
          "type": "DRUG"
        },
        {
          "name": "Nasal Washing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "2 Months to 2 Years"
      },
      "enrollment_count": 59,
      "start_date": "2003-12",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2016-06-01",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00435994"
    },
    {
      "nct_id": "NCT04773184",
      "title": "Improving Diagnostic Standards in Dysphagia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dysphagia"
      ],
      "interventions": [
        {
          "name": "Fiberoptic Endoscopic Evaluation of Swallowing",
          "type": "PROCEDURE"
        },
        {
          "name": "Videofluoroscopic Swallowing Study",
          "type": "PROCEDURE"
        },
        {
          "name": "Voluntary Peak Cough Flow Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Iowa Oral Performance Instrument",
          "type": "PROCEDURE"
        },
        {
          "name": "Capsaicin Challenge",
          "type": "PROCEDURE"
        },
        {
          "name": "Pulmonary Function Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Voicing Tasks",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 46,
      "start_date": "2021-04-27",
      "completion_date": "2023-09-23",
      "has_results": false,
      "last_update_posted_date": "2024-01-17",
      "last_synced_at": "2026-09-22T04:09:49.165Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04773184"
    }
  ]
}