{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Usual+Brand+combustible+cigarette&page=2",
    "query": {
      "intervention": "Usual Brand combustible cigarette",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 29,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Usual+Brand+combustible+cigarette&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Usual+Brand+combustible+cigarette&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T22:53:48.010Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06442384",
      "title": "Remote Trial - Tobacco Product Standard (VLNC)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Tobacco and non-tobacco e-cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Tobacco only e-cigarettes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Masonic Cancer Center, University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2024-09-11",
      "completion_date": "2025-04-07",
      "has_results": false,
      "last_update_posted_date": "2025-04-10",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06442384"
    },
    {
      "nct_id": "NCT07476144",
      "title": "Nicotine Pouch Pharmacokinetics Abuse Liability",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Smoking Behaviors"
      ],
      "interventions": [
        {
          "name": "Participants will place the pouch between their top lip and their gum for 30 minutes as per use instructions.",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "JT International SA",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 55,
      "start_date": "2026-01-08",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 2,
      "location_summary": "Knoxville, Tennessee • San Antonio, Texas",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07476144"
    },
    {
      "nct_id": "NCT04123041",
      "title": "Characterize the Nicotine Uptake and Subjective Effects With Use of JUUL Electronic Nicotine Delivery Systems",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "JUUL ENDS, Combustible cigarette, comparator e-cigarette, Nicorette gum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Juul Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 137,
      "start_date": "2019-09-23",
      "completion_date": "2019-12-18",
      "has_results": false,
      "last_update_posted_date": "2020-02-13",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 2,
      "location_summary": "Kansas City, Kansas • Lexington, Kentucky",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04123041"
    },
    {
      "nct_id": "NCT04019626",
      "title": "A Study to Assess Tobacco-related Biomarkers of Exposure in Smokers Using myBlu E-cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Continue-smoking",
          "type": "OTHER"
        },
        {
          "name": "myblu Tobacco 2.5%",
          "type": "OTHER"
        },
        {
          "name": "myblu Tobacco 4.0%",
          "type": "OTHER"
        },
        {
          "name": "myblu Honeymoon 2.5%",
          "type": "OTHER"
        },
        {
          "name": "myblu Honeymoon 4.0%",
          "type": "OTHER"
        },
        {
          "name": "JUUL 5%",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Fontem Ventures BV",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 240,
      "start_date": "2019-03-01",
      "completion_date": "2020-12-31",
      "has_results": true,
      "last_update_posted_date": "2021-06-30",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04019626"
    },
    {
      "nct_id": "NCT06476405",
      "title": "Room Air Levels of Harmful and Potentially Harmful Constituents After Heated Tobacco Product Use and Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tobacco Smoking",
        "Tobacco Use"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Altria Client Services LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 32,
      "start_date": "2024-06-10",
      "completion_date": "2025-03-11",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 1,
      "location_summary": "Stockbridge, Georgia",
      "locations": [
        {
          "city": "Stockbridge",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06476405"
    },
    {
      "nct_id": "NCT05457634",
      "title": "Nicotine Uptake and Abuse Liability Assessments of Blu Disposable Electronic Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Combustible Cigarette",
          "type": "OTHER"
        },
        {
          "name": "blu Disposable A",
          "type": "OTHER"
        },
        {
          "name": "blu Disposable B",
          "type": "OTHER"
        },
        {
          "name": "blu Disposable C",
          "type": "OTHER"
        },
        {
          "name": "blu Disposable D",
          "type": "OTHER"
        },
        {
          "name": "blu Disposable E",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Fontem US LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2021-07-13",
      "completion_date": "2024-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 1,
      "location_summary": "Burbank, California",
      "locations": [
        {
          "city": "Burbank",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05457634"
    },
    {
      "nct_id": "NCT04107779",
      "title": "Changes in Biomarkers of Cigarette Smoke Exposure After Switching Either Exclusively or Partly to JUUL ENDS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use",
        "Cigarette Use, Electronic",
        "Tobacco Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 5% Virginia Tobacco ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 3% Virginia Tobacco ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 5% Mint ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 3% Mint ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 5% Menthol ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 3% Menthol ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 5% Mango ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch from UB of Combustible Cigarette to JUUL 3% Mango ENDS",
          "type": "OTHER"
        },
        {
          "name": "Switch to Dual-use of JUUL 5% and UB of Combustible Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Tobacco/Nicotine Abstention",
          "type": "OTHER"
        },
        {
          "name": "Usual Brand of cigarettes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Juul Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 279,
      "start_date": "2019-09-17",
      "completion_date": "2020-06-24",
      "has_results": false,
      "last_update_posted_date": "2020-07-28",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 5,
      "location_summary": "Little Rock, Arkansas • Rogers, Arkansas • St Louis, Missouri + 2 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Rogers",
          "state": "Arkansas"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Dayton",
          "state": "Ohio"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04107779"
    },
    {
      "nct_id": "NCT03862924",
      "title": "Health Effects of the Standardized Research E-Cigarette in Smokers With HIV Smokers With HIV",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV"
      ],
      "interventions": [
        {
          "name": "Standardized Research Electronic Cigarette",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2022-03-01",
      "completion_date": "2024-12-30",
      "has_results": false,
      "last_update_posted_date": "2024-06-18",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03862924"
    },
    {
      "nct_id": "NCT03742817",
      "title": "Effects of e-Cigarettes on Perceptions and Behavior",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarettes"
      ],
      "interventions": [
        {
          "name": "e-Cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2019-02-01",
      "completion_date": "2020-03-01",
      "has_results": false,
      "last_update_posted_date": "2023-07-11",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03742817"
    },
    {
      "nct_id": "NCT06230159",
      "title": "Evaluating the Impact of Synthetic Cooling Agents in Combustible Cigarettes on Smoking Perceptions and Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking-Related Carcinoma"
      ],
      "interventions": [
        {
          "name": "Non-menthol Cigarette Smoking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Menthol Cigarette Smoking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Synthetic Cooling Agent Cigarette Smoking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Brand Cigarette Smoking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Spirometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Nasal Epithelial Lining Fluid",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "21 Years to 29 Years"
      },
      "enrollment_count": 34,
      "start_date": "2023-11-28",
      "completion_date": "2024-06-12",
      "has_results": true,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-10-07T22:53:48.010Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06230159"
    }
  ]
}