{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=VO2max.&page=2",
    "query": {
      "intervention": "VO2max.",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=VO2max.&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T00:07:45.842Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00536211",
      "title": "Physical Inactivity and Insulin Resistance in Skeletal Muscle.",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome X",
        "Insulin Resistance",
        "Hypertension",
        "Hypercholesterolemia",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Metformin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "20 Years to 55 Years"
      },
      "enrollment_count": 0,
      "start_date": "2009-06",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2021-05-04",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00536211"
    },
    {
      "nct_id": "NCT04514354",
      "title": "The Influence of Cardiorespiratory Fitness on Firefighter Cardiovascular Health Under Exercise Conditions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Post-Exercise Hypotension"
      ],
      "interventions": [
        {
          "name": "GEST",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Connecticut",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2015-04",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2020-08-14",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04514354"
    },
    {
      "nct_id": "NCT03380923",
      "title": "Precision High-Intensity Training Through Epigenetics (PHITE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Moderate Intensity",
          "type": "BEHAVIORAL"
        },
        {
          "name": "High Intensity",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "27 Years",
        "sex": "ALL",
        "summary": "18 Years to 27 Years"
      },
      "enrollment_count": 239,
      "start_date": "2017-02-23",
      "completion_date": "2021-07-31",
      "has_results": false,
      "last_update_posted_date": "2021-10-07",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03380923"
    },
    {
      "nct_id": "NCT06950060",
      "title": "AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke, Chronic",
        "Aging",
        "Cognitive Decline",
        "Motor Dysfunction",
        "Neuroplasticity"
      ],
      "interventions": [
        {
          "name": "High intensity cycling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low-intensity cycling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health education session",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Moderate Intensity Aerobic Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 48,
      "start_date": "2026-07-15",
      "completion_date": "2030-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06950060"
    },
    {
      "nct_id": "NCT00882141",
      "title": "Race, Menopause and Metabolism After Exercise and Diet",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Insulin Resistance",
        "Sedentary Lifestyle"
      ],
      "interventions": [
        {
          "name": "Diet modification",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Aerobic exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute on Aging (NIA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 80 Years · Female only"
      },
      "enrollment_count": 103,
      "start_date": "2002-03",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2010-01-13",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00882141"
    },
    {
      "nct_id": "NCT07516509",
      "title": "Determining Cell- and Spatially-distinct Skeletal Muscle Transcriptional Aberrations in Insulin Resistance",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "VO2 Max",
          "type": "OTHER"
        },
        {
          "name": "DEXA",
          "type": "OTHER"
        },
        {
          "name": "Peripheral Microvascular Reactivity",
          "type": "OTHER"
        },
        {
          "name": "Skeletal Muscle Insulin Sensitivity",
          "type": "OTHER"
        },
        {
          "name": "Non-Oxidative Glucose Disposal",
          "type": "OTHER"
        },
        {
          "name": "Muscle tissue Biopsy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "AdventHealth Translational Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2026-06-11",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-08-12",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07516509"
    },
    {
      "nct_id": "NCT03089047",
      "title": "Rejuvenated RBC and VO2 Max in Healthy Subjects",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Erythrocyte Transfusion"
      ],
      "interventions": [
        {
          "name": "Transfusion of rejuvenated and washed autolgous RBCs",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Transfusion of washed autolgous RBCs",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 9,
      "start_date": "2017-09-29",
      "completion_date": "2018-04-18",
      "has_results": true,
      "last_update_posted_date": "2021-01-11",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03089047"
    },
    {
      "nct_id": "NCT05043454",
      "title": "Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "High Intensity Interval Training (HIIT) Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "55 Years to 75 Years"
      },
      "enrollment_count": 11,
      "start_date": "2021-10-01",
      "completion_date": "2025-07-09",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05043454"
    },
    {
      "nct_id": "NCT03070184",
      "title": "Race, Natriuretic Peptides and Physiological Perturbations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Healthy",
        "Pre Hypertension"
      ],
      "interventions": [
        {
          "name": "Exercise capacity VO2 max determination",
          "type": "OTHER"
        },
        {
          "name": "Standardized meals",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Exercise challenge",
          "type": "OTHER"
        },
        {
          "name": "Metoprolol Succinate ER",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 80,
      "start_date": "2017-04-30",
      "completion_date": "2024-04-30",
      "has_results": true,
      "last_update_posted_date": "2025-03-12",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03070184"
    },
    {
      "nct_id": "NCT04026126",
      "title": "Effects of Passive Heat Therapy on Oxygen Consumption and Cardiovascular Fitness in Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure",
        "Heart Diseases",
        "Cardiovascular Diseases",
        "Endothelial Dysfunction"
      ],
      "interventions": [
        {
          "name": "Heat Therapy Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 15,
      "start_date": "2019-08-29",
      "completion_date": "2021-07-14",
      "has_results": true,
      "last_update_posted_date": "2022-10-17",
      "last_synced_at": "2026-09-05T00:07:45.842Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04026126"
    }
  ]
}