{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vagal+nerve+stimulation",
    "query": {
      "intervention": "Vagal nerve stimulation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 299,
    "total_pages": 30,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vagal+nerve+stimulation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T21:08:06.429Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07288411",
      "title": "Effects of Vagus Nerve Stimulation on Temporomandibular Disorders.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "TMD",
        "Temporomandibular Disorders (TMDs)"
      ],
      "interventions": [
        {
          "name": "nVNS Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Arpana Church",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2026-09-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-01",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07288411"
    },
    {
      "nct_id": "NCT04021797",
      "title": "Autonomic Mechanisms of Sleep-dependent Memory Consolidation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Memory",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "transcutaneous vagal nerve stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 12,
      "start_date": "2019-10-15",
      "completion_date": "2020-03-15",
      "has_results": true,
      "last_update_posted_date": "2026-09-15",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04021797"
    },
    {
      "nct_id": "NCT07516873",
      "title": "Exploring the Effects of Brief Mindfulness Training With Vagal Nerve Stimulation on Alcohol Cue Reactivity Among Young Adult Heavy Drinkers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heavy Drinking"
      ],
      "interventions": [
        {
          "name": "Active RAVANS",
          "type": "DEVICE"
        },
        {
          "name": "Brief Mindfulness-Based Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Cambridge Health Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "21 Years to 29 Years"
      },
      "enrollment_count": 50,
      "start_date": "2026-03-06",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 1,
      "location_summary": "Malden, Massachusetts",
      "locations": [
        {
          "city": "Malden",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07516873"
    },
    {
      "nct_id": "NCT04100486",
      "title": "Non-Invasive Bioelectronic Analytics",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autonomic Dysfunction",
        "Autonomic Imbalance",
        "Autonomic Nervous System Diseases",
        "Vagus Nerve Autonomic Disorder"
      ],
      "interventions": [
        {
          "name": "Standing-Squatting-Standing Test",
          "type": "OTHER"
        },
        {
          "name": "Deep Breathing Test",
          "type": "OTHER"
        },
        {
          "name": "Cold Pressor Test",
          "type": "OTHER"
        },
        {
          "name": "Cold Face Test",
          "type": "OTHER"
        },
        {
          "name": "Valsalva Maneuver",
          "type": "OTHER"
        },
        {
          "name": "Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 48,
      "start_date": "2019-08-29",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 1,
      "location_summary": "Manhasset, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04100486"
    },
    {
      "nct_id": "NCT02974959",
      "title": "Vagus Nerve Stimulation to Treat Moderate Traumatic Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Traumatic Brain Injury",
        "Acute Brain Injuries"
      ],
      "interventions": [
        {
          "name": "gammaCore active device",
          "type": "DEVICE"
        },
        {
          "name": "gammaCore sham device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CentraCare",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 14,
      "start_date": "2016-10",
      "completion_date": "2020-11",
      "has_results": false,
      "last_update_posted_date": "2021-02-04",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02974959"
    },
    {
      "nct_id": "NCT05866471",
      "title": "The ENHANCE Study: taVNS and Psilocybin",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy",
        "Psychedelic Experiences",
        "Vagus Nerve Stimulation"
      ],
      "interventions": [
        {
          "name": "Psilocybin",
          "type": "DRUG"
        },
        {
          "name": "Transcutaneous auricular Vagus Nerve Stimulation (taVNS)",
          "type": "DEVICE"
        },
        {
          "name": "Psychosocial Support Alone",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham taVNS",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 108,
      "start_date": "2025-01-27",
      "completion_date": "2028-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-29",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05866471"
    },
    {
      "nct_id": "NCT05316519",
      "title": "Transcutaneous Auricular Vagus Nerve Stimulation to Enhance Motor Learning",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurological Injury",
        "Motor Disorders",
        "Paresis"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Vagus Nerve Stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Pittsburgh Healthcare System",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 4,
      "start_date": "2022-06-01",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-05-09",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05316519"
    },
    {
      "nct_id": "NCT06360900",
      "title": "Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Support Therapy in Functional Dyspepsia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Functional Dyspepsia"
      ],
      "interventions": [
        {
          "name": "Sensory device",
          "type": "DEVICE"
        },
        {
          "name": "Skills Building",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health Education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Subsensory device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-10-29",
      "completion_date": "2029-03",
      "has_results": false,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06360900"
    },
    {
      "nct_id": "NCT07719387",
      "title": "Vagal Nerve Stimulation To Enhance Cognition and Learning",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vagus Nerve Stimulation",
        "Stroke",
        "Cognitive Assessment",
        "Language Acquisition"
      ],
      "interventions": [
        {
          "name": "VNS for Cognition",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-11-17",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07719387"
    },
    {
      "nct_id": "NCT06143293",
      "title": "RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epilepsy",
        "Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Vagus nerve stimulation device: acute and chronic administration of investigational vagus nerve stimulation parameters",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2023-12-15",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-09-23T21:08:06.429Z",
      "location_count": 5,
      "location_summary": "Stanford, California • Minneapolis, Minnesota • St Louis, Missouri + 2 more",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Lincoln",
          "state": "Nebraska"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06143293"
    }
  ]
}