{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vaginal+Progesterone+gel.",
    "query": {
      "intervention": "Vaginal Progesterone gel."
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vaginal+Progesterone+gel.&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-20T06:53:43.227Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02133573",
      "title": "Randomized Trial of Maternal Progesterone Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Congenital Heart Disease",
        "Periventricular Leucomalacia",
        "Brain Development",
        "Cardiac Surgery",
        "Neurodevelopmental Disability",
        "Fetal Neuroprotection"
      ],
      "interventions": [
        {
          "name": "Progesterone",
          "type": "DRUG"
        },
        {
          "name": "Vaginal lubricant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 102,
      "start_date": "2014-07",
      "completion_date": "2021-11",
      "has_results": true,
      "last_update_posted_date": "2023-08-09",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02133573"
    },
    {
      "nct_id": "NCT00615251",
      "title": "A Clinical Trial to Evaluate the Efficacy and Safety of DR-2011 for In Vitro Fertilization",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "DR-2011",
          "type": "DRUG"
        },
        {
          "name": "Crinone 8%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duramed Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "42 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 42 Years · Female only"
      },
      "enrollment_count": 1297,
      "start_date": "2008-02",
      "completion_date": "2009-08",
      "has_results": false,
      "last_update_posted_date": "2013-09-13",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 29,
      "location_summary": "Tarzana, California • West Los Angeles, California • Westlake, California + 26 more",
      "locations": [
        {
          "city": "Tarzana",
          "state": "California"
        },
        {
          "city": "West Los Angeles",
          "state": "California"
        },
        {
          "city": "Westlake",
          "state": "California"
        },
        {
          "city": "Clearwater",
          "state": "Florida"
        },
        {
          "city": "Alpharetta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00615251"
    },
    {
      "nct_id": "NCT00117468",
      "title": "Comparison of DR-2011 to a Progesterone Vaginal Gel for Luteal Phase Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "DR-2011",
          "type": "DRUG"
        },
        {
          "name": "Progesterone 8% Vaginal Gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duramed Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 20,
      "start_date": "2005-06",
      "completion_date": "2006-04",
      "has_results": false,
      "last_update_posted_date": "2014-05-12",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00117468"
    },
    {
      "nct_id": "NCT01546454",
      "title": "Relationship Between the Menstrual Cycle and Heart Disease in Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Heart Disease"
      ],
      "interventions": [
        {
          "name": "Ethinyl Estradiol-Levonorgestrel combination",
          "type": "DRUG"
        },
        {
          "name": "leuprolide acetate",
          "type": "DRUG"
        },
        {
          "name": "Estradiol",
          "type": "DRUG"
        },
        {
          "name": "Progesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 40 Years · Female only"
      },
      "enrollment_count": 5,
      "start_date": "2012-02",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2017-03-22",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01546454"
    },
    {
      "nct_id": "NCT02772120",
      "title": "Comparison of Vaginal and Intramuscular Progesterone in Vitrified-warmed Blastocyst Transfer Cycles",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "Vaginal progesterone gel (Crinone® 8%)",
          "type": "DRUG"
        },
        {
          "name": "Intramuscular Progesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2019-09-09",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02772120"
    },
    {
      "nct_id": "NCT00656201",
      "title": "Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "Crinone 8% Vaginal Gel",
          "type": "DRUG"
        },
        {
          "name": "Intramuscular Progesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "39 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 39 Years · Female only"
      },
      "enrollment_count": 468,
      "start_date": "2003-07",
      "completion_date": "2009-07",
      "has_results": true,
      "last_update_posted_date": "2011-09-22",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00656201"
    },
    {
      "nct_id": "NCT01812239",
      "title": "Vaginal Progesterone in Twins With Short Cervix",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "Vaginal Progesterone gel.",
          "type": "DRUG"
        },
        {
          "name": "fetal fibronectin swab.",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Obstetrix Medical Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2014-03",
      "completion_date": "2018-08",
      "has_results": false,
      "last_update_posted_date": "2014-12-19",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 1,
      "location_summary": "San Jose, California",
      "locations": [
        {
          "city": "San Jose",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01812239"
    },
    {
      "nct_id": "NCT04549116",
      "title": "Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infertility"
      ],
      "interventions": [
        {
          "name": "Progesterone-IBSA Injectable Solution",
          "type": "DRUG"
        },
        {
          "name": "Progesterone Vaginal Gel with Applicator",
          "type": "DRUG"
        },
        {
          "name": "Placebo Vaginal gel with applicator",
          "type": "DRUG"
        },
        {
          "name": "Placebo injectable solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "IBSA Institut Biochimique SA",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "42 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 42 Years · Female only"
      },
      "enrollment_count": 688,
      "start_date": "2022-10-12",
      "completion_date": "2026-08-25",
      "has_results": false,
      "last_update_posted_date": "2026-08-27",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 24,
      "location_summary": "Tempe, Arizona • Encino, California • Los Angeles, California + 20 more",
      "locations": [
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "Encino",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04549116"
    },
    {
      "nct_id": "NCT01406197",
      "title": "Uterine Electrical Activity Before and After Progesterone Treatment for Preterm Labor",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preterm Labor"
      ],
      "interventions": [
        {
          "name": "Experimental: Vaginal progesterone",
          "type": "DRUG"
        },
        {
          "name": "Experimental: Topical progesterone",
          "type": "DRUG"
        },
        {
          "name": "Experimental: Intramuscular progesterone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Joseph's Hospital and Medical Center, Phoenix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "17 Years to 40 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2011-07",
      "completion_date": "2013-10",
      "has_results": false,
      "last_update_posted_date": "2022-10-26",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01406197"
    },
    {
      "nct_id": "NCT03440359",
      "title": "Vaginal Progesterone Supplementation in Women With PCOS Undergoing Ovulation Induction With Letrozole",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Polycystic Ovary Syndrome"
      ],
      "interventions": [
        {
          "name": "Progesterone Vaginal Gel 8%",
          "type": "DRUG"
        },
        {
          "name": "Letrozole Oral Tablet",
          "type": "DRUG"
        },
        {
          "name": "pelvic ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Ovidrel 250 MCG Per 0.5 ML Prefilled Syringe",
          "type": "DRUG"
        },
        {
          "name": "Intrauterine insemination or timed intercourse",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Eastern Virginia Medical School",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 40 Years · Female only"
      },
      "enrollment_count": 52,
      "start_date": "2012-07-06",
      "completion_date": "2017-12-30",
      "has_results": false,
      "last_update_posted_date": "2018-02-26",
      "last_synced_at": "2026-09-20T06:53:43.227Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03440359"
    }
  ]
}