{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vancomycin+concentrations",
    "query": {
      "intervention": "Vancomycin concentrations"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 19,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vancomycin+concentrations&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T05:19:43.810Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04662632",
      "title": "Abbreviated Protocol for Two-Stage Exchange",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Prosthetic Joint Infection"
      ],
      "interventions": [
        {
          "name": "VT-X7 Treatment System with Tobramycin Sulfate",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Standard of Care",
          "type": "DRUG"
        },
        {
          "name": "Two-stage exchange arthroplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "VT-X7 Treatment System with Vancomycin Hydrochloride",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Osteal Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "22 Years to 84 Years"
      },
      "enrollment_count": 76,
      "start_date": "2021-11-01",
      "completion_date": "2023-12-22",
      "has_results": true,
      "last_update_posted_date": "2026-04-21",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 17,
      "location_summary": "Phoenix, Arizona • Torrance, California • Washington D.C., District of Columbia + 13 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Weston",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04662632"
    },
    {
      "nct_id": "NCT05429671",
      "title": "Antibiotic Loaded Cement After TKA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Total Knee Arthoplasty"
      ],
      "interventions": [
        {
          "name": "total knee arthroplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "Tobramycin",
          "type": "DRUG"
        },
        {
          "name": "Gentamicin",
          "type": "DRUG"
        },
        {
          "name": "Antibiotic cement spacer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Rothman Institute Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2022-06-20",
      "completion_date": "2023-11-30",
      "has_results": false,
      "last_update_posted_date": "2024-04-30",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05429671"
    },
    {
      "nct_id": "NCT07339215",
      "title": "Local Antibiotic Concentrations With Tissue Expanders in Breast Reconstruction",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tissue Expander Based Breast Reconstruction"
      ],
      "interventions": [
        {
          "name": "Antibiotic loaded calcium sulfate beads",
          "type": "DEVICE"
        },
        {
          "name": "Polymethylmethacrylate antibiotic disc",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2026-07-01",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-14",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07339215"
    },
    {
      "nct_id": "NCT07084129",
      "title": "Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "personalized dosing adjustment of vancomycin",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "1 Month to 17 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-04-15",
      "completion_date": "2027-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07084129"
    },
    {
      "nct_id": "NCT01645735",
      "title": "Evaluation of Ceftaroline Fosamil Versus a Comparator in Adult Subjects With Community-acquired Bacterial Pneumonia (CABP) With Risk for Methicillin-resistant Staphylococcus Aureus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Infections"
      ],
      "interventions": [
        {
          "name": "Ceftaroline fosamil",
          "type": "DRUG"
        },
        {
          "name": "Ceftriaxone plus vancomycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Forest Laboratories",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2012-10",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2016-02-01",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 13,
      "location_summary": "Phoenix, Arizona • Sylmar, California • DeLand, Florida + 10 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Sylmar",
          "state": "California"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01645735"
    },
    {
      "nct_id": "NCT03721328",
      "title": "Safety and Efficacy in Patients Treated for Hip or Knee PJI With Vancomycin and Tobramycin Joint Irrigation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Prosthetic Joint Infection"
      ],
      "interventions": [
        {
          "name": "vancomycin hydrochloride and tobramycin sulfate",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Osteal Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2018-10-26",
      "completion_date": "2020-08-25",
      "has_results": true,
      "last_update_posted_date": "2022-01-11",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 4,
      "location_summary": "Saginaw, Michigan • Charlotte, North Carolina • Oklahoma City, Oklahoma + 1 more",
      "locations": [
        {
          "city": "Saginaw",
          "state": "Michigan"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03721328"
    },
    {
      "nct_id": "NCT01932034",
      "title": "Prospective Study to Optimize Vancomycin Dosing in Children and Adults Using Computer Software",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bacterial Infections"
      ],
      "interventions": [
        {
          "name": "BestDose Computer Software",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 263,
      "start_date": "2012-09",
      "completion_date": "2016-07-04",
      "has_results": false,
      "last_update_posted_date": "2018-02-20",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01932034"
    },
    {
      "nct_id": "NCT03453684",
      "title": "Pharmacokinetics of Preoperative Vancomycin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Surgical Site Infection",
        "Vancomycin"
      ],
      "interventions": [
        {
          "name": "Administration of Vancomycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "31 Days",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "31 Days to 18 Years"
      },
      "enrollment_count": 60,
      "start_date": "2012-12-01",
      "completion_date": "2015-07-20",
      "has_results": true,
      "last_update_posted_date": "2022-05-24",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03453684"
    },
    {
      "nct_id": "NCT04673877",
      "title": "Vancomycin Tissue Concentrations by Bier Block or Intravenous Administration",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Infection",
        "Hand Injury Wrist",
        "Hand Injuries",
        "Hand Injuries and Disorders",
        "Hand Arthritis"
      ],
      "interventions": [
        {
          "name": "Systemic IV Vancomycin",
          "type": "DRUG"
        },
        {
          "name": "Bier Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Vancomycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2021-08-26",
      "completion_date": "2022-08-17",
      "has_results": false,
      "last_update_posted_date": "2022-10-07",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04673877"
    },
    {
      "nct_id": "NCT05079620",
      "title": "Early Antibiotics After Aspiration in ICU Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Aspiration",
        "Aspiration Pneumonia"
      ],
      "interventions": [
        {
          "name": "Ceftriaxone",
          "type": "DRUG"
        },
        {
          "name": "Amoxicillin clavulanic acid",
          "type": "DRUG"
        },
        {
          "name": "Cefepime",
          "type": "DRUG"
        },
        {
          "name": "Vancomycin",
          "type": "DRUG"
        },
        {
          "name": "Levofloxacin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2021-11-30",
      "completion_date": "2024-04-12",
      "has_results": true,
      "last_update_posted_date": "2025-12-30",
      "last_synced_at": "2026-09-04T05:19:43.810Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05079620"
    }
  ]
}