{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Varenicline+1mg+BID", "query": { "intervention": "Varenicline 1mg BID" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 38, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Varenicline+1mg+BID&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-28T09:39:11.432Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05703672", "title": "Switching to E-cigarettes in Smokers Not Interested in Quitting", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Smoking Reduction" ], "interventions": [ { "name": "Varenicline Tartrate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Electronic cigarette", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Kansas Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 500, "start_date": "2023-07-17", "completion_date": "2027-02-28", "has_results": false, "last_update_posted_date": "2025-12-29", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 2, "location_summary": "Kansas City, Missouri", "locations": [ { "city": "Kansas City", "state": "Missouri" }, { "city": "Kansas City", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05703672" }, { "nct_id": "NCT00879177", "title": "Smoking Study With Behavioral Therapy for Hypertensive Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cigarette Smoking", "Hypertension" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "behavioral therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "UConn Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 203, "start_date": "2009-04", "completion_date": "2014-11", "has_results": false, "last_update_posted_date": "2017-04-10", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 1, "location_summary": "Farmington, Connecticut", "locations": [ { "city": "Farmington", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00879177" }, { "nct_id": "NCT00285012", "title": "Smoking Cessation in Subjects With Mild-to-moderate Chronic Obstructive Pulmonary Disease (COPD).", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Smoking Cessation" ], "interventions": [ { "name": "placebo", "type": "DRUG" }, { "name": "Varenicline Tartarate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "35 Years", "maximum_age": null, "sex": "ALL", "summary": "35 Years and older" }, "enrollment_count": 504, "start_date": "2006-05", "completion_date": "2009-04", "has_results": true, "last_update_posted_date": "2010-04-20", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 22, "location_summary": "Birmingham, Alabama • Los Angeles, California • Denver, Colorado + 15 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Farmington", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00285012" }, { "nct_id": "NCT00894166", "title": "Evaluation of a Tailored Smoking Cessation Treatment Algorithm Based on Initial Treatment Response and Genotype", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Smoking Cessation" ], "interventions": [ { "name": "Nicotine Patches", "type": "DRUG" }, { "name": "Nicotine patches, then bupropion & nicotine patches (Pre-Quit)", "type": "DRUG" }, { "name": "Nicotine patches, then varenicline (Pre-Quit)", "type": "DRUG" }, { "name": "Nicotine patches, then nicotine patches (Pre-Quit)", "type": "DRUG" }, { "name": "Nicotine patches, then bupropion & nicotine patches (Post-Quit)", "type": "DRUG" }, { "name": "Nicotine patches, then varenicline (Post-Quit)", "type": "DRUG" }, { "name": "Nicotine patches, then nicotine patches (Post-Quit)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 606, "start_date": "2009-05", "completion_date": "2011-10", "has_results": true, "last_update_posted_date": "2013-09-23", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 1, "location_summary": "Charlotte, Durham, Raleigh, Winston-Salem, North Carolina", "locations": [ { "city": "Charlotte, Durham, Raleigh, Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00894166" }, { "nct_id": "NCT00580398", "title": "Smoking Cessation Intervention for Thoracic Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Lung Cancer" ], "interventions": [ { "name": "Smoking cessation counseling", "type": "BEHAVIORAL" }, { "name": "varenicline", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 49, "start_date": "2008-01", "completion_date": "2012-04", "has_results": true, "last_update_posted_date": "2018-10-12", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00580398" }, { "nct_id": "NCT01312909", "title": "Smoking Cessation Study In Healthy Adolescent Smokers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking Cessation" ], "interventions": [ { "name": "Varenicline 1mg BID", "type": "DRUG" }, { "name": "Varenicline 0.5mg BID", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "19 Years", "sex": "ALL", "summary": "12 Years to 19 Years" }, "enrollment_count": 312, "start_date": "2011-04", "completion_date": "2018-01", "has_results": true, "last_update_posted_date": "2018-08-09", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 56, "location_summary": "Ozark, Alabama • Goodyear, Arizona • Little Rock, Arkansas + 46 more", "locations": [ { "city": "Ozark", "state": "Alabama" }, { "city": "Goodyear", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "La Habra", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01312909" }, { "nct_id": "NCT05294263", "title": "Varenicline for the Treatment of Cannabis and Tobacco Use Disorders in Veterans", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Tobacco Use Disorder", "Cannabis Use Disorder" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2023-04-17", "completion_date": "2024-07-17", "has_results": false, "last_update_posted_date": "2024-08-27", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05294263" }, { "nct_id": "NCT04634071", "title": "Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Smoking Cessation", "Cancer, Treatment-Related" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Long-acting nicotine replacement therapy", "type": "DRUG" }, { "name": "Low-intensity counseling", "type": "BEHAVIORAL" }, { "name": "High-intensity counseling", "type": "BEHAVIORAL" }, { "name": "No nicotine replacement therapy", "type": "OTHER" }, { "name": "Nicotine Replacement Products", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BEHAVIORAL", "OTHER" ], "sponsor": "Joseph Valentino, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 126, "start_date": "2021-01-12", "completion_date": "2026-01-02", "has_results": false, "last_update_posted_date": "2026-02-02", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 3, "location_summary": "Bowling Green, Kentucky • Lexington, Kentucky • Owensboro, Kentucky", "locations": [ { "city": "Bowling Green", "state": "Kentucky" }, { "city": "Lexington", "state": "Kentucky" }, { "city": "Owensboro", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT04634071" }, { "nct_id": "NCT01244061", "title": "A Multi-National Study To Assess How Effective And Safe The Smoking Cessation Medicine Varenicline Is In Smokers Who Have Already Tried Varenicline In The Past As A Prescription Medicine From Their Usual Healthcare Provider", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking Cessation" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 498, "start_date": "2010-12", "completion_date": "2012-11", "has_results": true, "last_update_posted_date": "2014-06-09", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 8, "location_summary": "Los Angeles, California • DeLand, Florida • Lexington, Kentucky + 4 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "DeLand", "state": "Florida" }, { "city": "Lexington", "state": "Kentucky" }, { "city": "College Park", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01244061" }, { "nct_id": "NCT01456936", "title": "Study Evaluating The Safety And Efficacy Of Varenicline and Bupropion For Smoking Cessation In Subjects With And Without A History Of Psychiatric Disorders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking Cessation" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "varenicline tartrate", "type": "DRUG" }, { "name": "bupropion hydrochloride", "type": "DRUG" }, { "name": "Nicotine Replacement Therapy Patch", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 8144, "start_date": "2011-11", "completion_date": "2015-01", "has_results": true, "last_update_posted_date": "2016-06-10", "last_synced_at": "2026-09-28T09:39:11.432Z", "location_count": 77, "location_summary": "Mobile, Alabama • Phoenix, Arizona • Encino, California + 61 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Encino", "state": "California" }, { "city": "Escondido", "state": "California" }, { "city": "Imperial", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01456936" } ] }