{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Varithena",
    "query": {
      "intervention": "Varithena"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 18,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Varithena&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T06:22:02.696Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01428076",
      "title": "Pharmacokinetic Study of Polidocanol Endovenous Microfoam (PEM)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Varicose Veins"
      ],
      "interventions": [
        {
          "name": "Polidocanol Endovenous Microfoam (PEM)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 21,
      "start_date": "2011-08",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2021-04-21",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 1,
      "location_summary": "Bradenton, Florida",
      "locations": [
        {
          "city": "Bradenton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01428076"
    },
    {
      "nct_id": "NCT03257254",
      "title": "Effect of VarIthena on Wound Healing in Venous Leg Ulcers (VLU)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Varithena",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 76,
      "start_date": "2017-09-29",
      "completion_date": "2020-09-28",
      "has_results": true,
      "last_update_posted_date": "2021-12-14",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 13,
      "location_summary": "Palo Alto, California • Sacramento, California • Darien, Connecticut + 10 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Darien",
          "state": "Connecticut"
        },
        {
          "city": "Aventura",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03257254"
    },
    {
      "nct_id": "NCT00843466",
      "title": "Compatibility of a Mild, Moisturizing Hand Cleanser for Patients With Mild to Moderate Hand Dermatitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hand Dermatosis"
      ],
      "interventions": [
        {
          "name": "Mild, moisturizing hand cleanser",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 46,
      "start_date": "2007-05",
      "completion_date": "2008-11",
      "has_results": true,
      "last_update_posted_date": "2018-09-10",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00843466"
    },
    {
      "nct_id": "NCT01231373",
      "title": "Polidocanol Endovenous Microfoam (PEM) Versus Vehicle for the Treatment of Saphenofemoral Junction (SFJ) Incompetence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Varicose Veins"
      ],
      "interventions": [
        {
          "name": "polidocanol injectable foam, 0.125%",
          "type": "DRUG"
        },
        {
          "name": "polidocanol injectable foam, 0.5%",
          "type": "DRUG"
        },
        {
          "name": "polidocanol injectable foam, 1.0%",
          "type": "DRUG"
        },
        {
          "name": "Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 235,
      "start_date": "2010-11",
      "completion_date": "2014-08",
      "has_results": true,
      "last_update_posted_date": "2021-04-21",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 12,
      "location_summary": "Dothan, Alabama • San Diego, California • Lafayette, Indiana + 8 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Lafayette",
          "state": "Indiana"
        },
        {
          "city": "Frederick",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01231373"
    },
    {
      "nct_id": "NCT01197833",
      "title": "Endovenous Ablation With and Without Polidocanol Endovenous Microfoam Treatment for Patients With Great Saphenous Vein Incompetence and Visible Varicosities",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Great Saphenous Vein Incompetence",
        "Visible Varicosities"
      ],
      "interventions": [
        {
          "name": "endovenous ablation+polidocanol injectable microfoam 0.125%",
          "type": "DRUG"
        },
        {
          "name": "Endovenous ablation+polidocanol injectable microfoam 1.0%",
          "type": "DRUG"
        },
        {
          "name": "Endovenous ablation+polidocanol injectable foam 2.0%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 117,
      "start_date": "2010-09",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2021-04-21",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 7,
      "location_summary": "Scottsdale, Arizona • Bradenton, Florida • Oak Brook, Illinois + 4 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Oak Brook",
          "state": "Illinois"
        },
        {
          "city": "North Tonawanda",
          "state": "New York"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01197833"
    },
    {
      "nct_id": "NCT06120036",
      "title": "Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Neurofibromatosis 1"
      ],
      "interventions": [
        {
          "name": "Kybella",
          "type": "DRUG"
        },
        {
          "name": "Asclera",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 20,
      "start_date": "2022-12-06",
      "completion_date": "2025-01-09",
      "has_results": false,
      "last_update_posted_date": "2025-02-21",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06120036"
    },
    {
      "nct_id": "NCT03043534",
      "title": "Pre-Shave Gel and Brush in Pseudofolliculitis Barbae",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pseudofolliculitis Barbae"
      ],
      "interventions": [
        {
          "name": "shave gel",
          "type": "OTHER"
        },
        {
          "name": "Brush",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "60 Years",
        "sex": "MALE",
        "summary": "20 Years to 60 Years · Male only"
      },
      "enrollment_count": 29,
      "start_date": "2015-11-12",
      "completion_date": "2016-10-12",
      "has_results": true,
      "last_update_posted_date": "2018-12-19",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03043534"
    },
    {
      "nct_id": "NCT02988063",
      "title": "Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Leg Ulcer",
        "Veins, Varicose",
        "Venous Ulcer",
        "Reflux",
        "Venous Reflux",
        "Venous Leg Ulcer",
        "Varicose Veins",
        "Varicose Ulcer",
        "Varicose Veins Leg"
      ],
      "interventions": [
        {
          "name": "Polidocanol Endovenous Microfoam (PEM)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "OhioHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2017-04-10",
      "completion_date": "2017-09-12",
      "has_results": false,
      "last_update_posted_date": "2017-09-15",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02988063"
    },
    {
      "nct_id": "NCT02462720",
      "title": "COMFORT: A Multicenter, Open-label, Randomized, Crossover Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Varicose Veins"
      ],
      "interventions": [
        {
          "name": "Varithena®",
          "type": "DRUG"
        },
        {
          "name": "Radiofrequency ablation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 35,
      "start_date": "2015-05",
      "completion_date": "2016-03",
      "has_results": true,
      "last_update_posted_date": "2021-04-21",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 4,
      "location_summary": "Pensacola, Florida • Melrose Park, Illinois • Amherst, New York + 1 more",
      "locations": [
        {
          "city": "Pensacola",
          "state": "Florida"
        },
        {
          "city": "Melrose Park",
          "state": "Illinois"
        },
        {
          "city": "Amherst",
          "state": "New York"
        },
        {
          "city": "Bellevue",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02462720"
    },
    {
      "nct_id": "NCT05312970",
      "title": "Varithena Versus Endothermal Ablation of the Great Saphenous Vein (VERITAS)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Varicose Veins"
      ],
      "interventions": [
        {
          "name": "Varithena®",
          "type": "DRUG"
        },
        {
          "name": "FDA-approved Endothermal Ablation (ETA) systems",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2023-02-10",
      "completion_date": "2024-04-04",
      "has_results": true,
      "last_update_posted_date": "2026-03-20",
      "last_synced_at": "2026-09-06T06:22:02.696Z",
      "location_count": 9,
      "location_summary": "Darien, Connecticut • Washington D.C., District of Columbia • Houma, Louisiana + 6 more",
      "locations": [
        {
          "city": "Darien",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Houma",
          "state": "Louisiana"
        },
        {
          "city": "South Portland",
          "state": "Maine"
        },
        {
          "city": "Englewood",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05312970"
    }
  ]
}