{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vehicle+%28Placebo+solution%29&page=2", "query": { "intervention": "Vehicle (Placebo solution)", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vehicle+%28Placebo+solution%29&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-27T22:22:39.268Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06441643", "title": "Next Generation Rocklatan", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Open Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "AR-17043 Ophthalmic Solution", "type": "DRUG" }, { "name": "PG043 Ophthalmic Solution", "type": "DRUG" }, { "name": "Latanoprost 0.005% Ophthalmic Solution", "type": "DRUG" }, { "name": "Netarsudil 0.02% Ophthalmic Solution", "type": "DRUG" }, { "name": "Netarsudil 0.02%/Latanoprost 0.005% Ophthalmic Solution", "type": "DRUG" }, { "name": "AR-17043 Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 426, "start_date": "2024-09-04", "completion_date": "2025-11-14", "has_results": false, "last_update_posted_date": "2025-11-18", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 12, "location_summary": "Garden Grove, California • Inglewood, California • Newport Beach, California + 9 more", "locations": [ { "city": "Garden Grove", "state": "California" }, { "city": "Inglewood", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Petaluma", "state": "California" }, { "city": "Fort Collins", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT06441643" }, { "nct_id": "NCT01320553", "title": "Effect of Different Concentrations of SPARC1102 on Allergic Conjunctivitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Allergic Conjunctivitis" ], "interventions": [ { "name": "SPARC1102 I", "type": "DRUG" }, { "name": "SPARC1102 II", "type": "DRUG" }, { "name": "SPARC1102 III", "type": "DRUG" }, { "name": "Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sun Pharma Advanced Research Company Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": null, "sex": "ALL", "summary": "10 Years and older" }, "enrollment_count": 122, "start_date": "2011-06", "completion_date": "2011-09", "has_results": true, "last_update_posted_date": "2016-06-24", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 1, "location_summary": "Andover, Massachusetts", "locations": [ { "city": "Andover", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01320553" }, { "nct_id": "NCT01275105", "title": "A Single-Center, Randomized, Double-Masked, Placebo and Active Controlled, Dose-Ranging Evaluation of the Duration of Action of Brimonidine Tartrate Ophthalmic Solution in the Control of Ocular Redness Induced by Conjunctival Allergen Challenge (CAC)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Allergic Conjunctivitis" ], "interventions": [ { "name": "Vehicle", "type": "DRUG" }, { "name": "Brimonidine Tartrate 0.01%", "type": "DRUG" }, { "name": "Brimonidine Tartrate 0.025%", "type": "DRUG" }, { "name": "Oxymetazoline HCl 0.025%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eye Therapies, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 68, "start_date": "2011-01", "completion_date": "2011-03", "has_results": false, "last_update_posted_date": "2012-03-06", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 1, "location_summary": "Andover, Massachusetts", "locations": [ { "city": "Andover", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01275105" }, { "nct_id": "NCT00198445", "title": "Safety and Efficacy Study of Topical Bromfenac Versus Placebo to Treat Ocular Inflammation After Cataract Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Complications", "Cataract" ], "interventions": [ { "name": "Bromfenac", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 527, "start_date": "2003-05", "completion_date": "2004-01", "has_results": false, "last_update_posted_date": "2013-03-14", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 39, "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Irvine, California + 34 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Irvine", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00198445" }, { "nct_id": "NCT00902200", "title": "A Study of AR-12286 in Patient With Elevated Intraocular Pressure (IOP)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Elevated Intraocular Pressure" ], "interventions": [ { "name": "AR-12286", "type": "DRUG" }, { "name": "AR-12286 vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aerie Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 89, "start_date": "2009-05", "completion_date": "2009-09", "has_results": false, "last_update_posted_date": "2014-04-21", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 8, "location_summary": "Pasadena, California • Petaluma, California • Brooksville, Florida + 5 more", "locations": [ { "city": "Pasadena", "state": "California" }, { "city": "Petaluma", "state": "California" }, { "city": "Brooksville", "state": "Florida" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Charlotte", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00902200" }, { "nct_id": "NCT04268069", "title": "Efficacy and Safety of PL9643 Ophthalmic Solution in Subjects With Dry Eye", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dry Eye Disease" ], "interventions": [ { "name": "PL9643 Ophthalmic Solution", "type": "DRUG" }, { "name": "Placebo Ophthalmic Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "ORA, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 160, "start_date": "2020-02-14", "completion_date": "2020-10-05", "has_results": false, "last_update_posted_date": "2020-11-13", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 4, "location_summary": "Andover, Massachusetts • Raynham, Massachusetts • Shelby, North Carolina + 1 more", "locations": [ { "city": "Andover", "state": "Massachusetts" }, { "city": "Raynham", "state": "Massachusetts" }, { "city": "Shelby", "state": "North Carolina" }, { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04268069" }, { "nct_id": "NCT02405039", "title": "Study of EBI-005 in Dry Eye Disease (DED)", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Dry Eye" ], "interventions": [ { "name": "EBI-005", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eleven Biotherapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 188, "start_date": "2015-04", "completion_date": "2016-07", "has_results": false, "last_update_posted_date": "2015-06-04", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 12, "location_summary": "Birmingham, Alabama • Newport Beach, California • Hamden, Connecticut + 9 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Newport Beach", "state": "California" }, { "city": "Hamden", "state": "Connecticut" }, { "city": "New Albany", "state": "Indiana" }, { "city": "Louisville", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT02405039" }, { "nct_id": "NCT04097730", "title": "Steroids and Cross-linking for Ulcer Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Keratitis Bacterial" ], "interventions": [ { "name": "Moxifloxacin Ophthalmic", "type": "DRUG" }, { "name": "Difluprednate Ophthalmic", "type": "DRUG" }, { "name": "Riboflavin Ophthalmic", "type": "DRUG" }, { "name": "Topical Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Thomas M. Lietman", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 280, "start_date": "2020-09-24", "completion_date": "2024-09-18", "has_results": false, "last_update_posted_date": "2025-02-03", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 2, "location_summary": "San Francisco, California • Miami, Florida", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04097730" }, { "nct_id": "NCT04084483", "title": "A Study Assessing the Safety, Efficacy, and Optimum Dosage of K-161 in Subjects With Moderate to Severe Dry Eye Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dry Eye Disease" ], "interventions": [ { "name": "K-161", "type": "DRUG" }, { "name": "Placebo (Vehicle)", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Kowa Research Institute, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 238, "start_date": "2019-08-04", "completion_date": "2020-01-09", "has_results": true, "last_update_posted_date": "2023-03-15", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 4, "location_summary": "Newport Beach, California • Lewiston, Maine • Andover, Massachusetts + 1 more", "locations": [ { "city": "Newport Beach", "state": "California" }, { "city": "Lewiston", "state": "Maine" }, { "city": "Andover", "state": "Massachusetts" }, { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04084483" }, { "nct_id": "NCT05467293", "title": "Phase 2, Multi-center, Randomized, Double- Masked and Placebo-Controlled Study of YP-P10 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye (ICECAP 1)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dry Eye" ], "interventions": [ { "name": "0.3% YP-P10 Ophthalmic Solution", "type": "DRUG" }, { "name": "1% YP-P10 Ophthalmic Solution", "type": "DRUG" }, { "name": "YP-P10 Placebo Ophthalmic Solution (vehicle)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yuyu Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 257, "start_date": "2022-06-27", "completion_date": "2023-03-06", "has_results": true, "last_update_posted_date": "2024-07-30", "last_synced_at": "2026-09-27T22:22:39.268Z", "location_count": 7, "location_summary": "Phoenix, Arizona • Newport Beach, California • Colorado Springs, Colorado + 4 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Newport Beach", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Andover", "state": "Massachusetts" }, { "city": "Apex", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05467293" } ] }