{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vehicle+cream+%28placebo%29&page=3",
    "query": {
      "intervention": "Vehicle cream (placebo)",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 104,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vehicle+cream+%28placebo%29&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vehicle+cream+%28placebo%29&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-10T22:00:36.339Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03142178",
      "title": "3VM for Treatment of Chronic Osteoarthritis Knee Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Arthritis, Degenerative"
      ],
      "interventions": [
        {
          "name": "Experimental: 3VM1001 active 2g Cream 3 times daily",
          "type": "DRUG"
        },
        {
          "name": "Experimental: 3VM1001 active 3g Cream 3 times daily",
          "type": "DRUG"
        },
        {
          "name": "Experimental: 3VM1001 active 3g Cream 4 times daily",
          "type": "DRUG"
        },
        {
          "name": "Placebo: 3VM1001 vehicle 2g Cream 3 times daily",
          "type": "DRUG"
        },
        {
          "name": "Placebo: 3VM1001 vehicle 3g Cream 3 times daily",
          "type": "DRUG"
        },
        {
          "name": "Placebo: 3VM1001 vehicle 3g Cream 4 times daily",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "CDA Research Group, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2017-04-30",
      "completion_date": "2018-06-01",
      "has_results": false,
      "last_update_posted_date": "2018-07-06",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03142178"
    },
    {
      "nct_id": "NCT05550337",
      "title": "Study Comparing Trifarotene Cream, 0.005% To AKLIEF ® (Trifarotene 0.005% Cream) In The Treatment Of Acne Vulgaris",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acne Vulgaris"
      ],
      "interventions": [
        {
          "name": "Trifarotene 0.005 % Topical Cream",
          "type": "DRUG"
        },
        {
          "name": "AKLIEF®",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Teva Pharmaceuticals USA",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "12 Years to 40 Years"
      },
      "enrollment_count": 807,
      "start_date": "2022-09-19",
      "completion_date": "2023-05-09",
      "has_results": true,
      "last_update_posted_date": "2024-09-26",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 14,
      "location_summary": "West Covina, California • Brandon, Florida • Fort Lauderdale, Florida + 9 more",
      "locations": [
        {
          "city": "West Covina",
          "state": "California"
        },
        {
          "city": "Brandon",
          "state": "Florida"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miramar",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05550337"
    },
    {
      "nct_id": "NCT04378569",
      "title": "Safety and Efficacy of ARQ-252 Cream in Subjects With Chronic Hand Eczema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chronic Hand Eczema"
      ],
      "interventions": [
        {
          "name": "ARQ-252 cream 0.3%",
          "type": "DRUG"
        },
        {
          "name": "ARQ-252 cream 0.1%",
          "type": "DRUG"
        },
        {
          "name": "ARQ-252 Vehicle Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Arcutis Biotherapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 230,
      "start_date": "2020-04-20",
      "completion_date": "2021-02-24",
      "has_results": true,
      "last_update_posted_date": "2024-04-05",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 25,
      "location_summary": "Beverly Hills, California • Encino, California • Fremont, California + 21 more",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Encino",
          "state": "California"
        },
        {
          "city": "Fremont",
          "state": "California"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04378569"
    },
    {
      "nct_id": "NCT01347879",
      "title": "A Double Blinded, Prospective, Randomized, Vehicle Controlled Multi-center Study of Photodynamic Therapy With Visonac® Cream in Patients With Acne Vulgaris",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acne Vulgaris"
      ],
      "interventions": [
        {
          "name": "Visonac PDT",
          "type": "DRUG"
        },
        {
          "name": "Vehicle cream with PDT",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Photocure",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "12 Years to 35 Years"
      },
      "enrollment_count": 153,
      "start_date": "2011-05",
      "completion_date": "2012-05",
      "has_results": true,
      "last_update_posted_date": "2014-01-16",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 15,
      "location_summary": "Oceanside, California • San Diego, California • Jacksonville, Florida + 12 more",
      "locations": [
        {
          "city": "Oceanside",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Arlington Heights",
          "state": "Illinois"
        },
        {
          "city": "Naperville",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01347879"
    },
    {
      "nct_id": "NCT05212246",
      "title": "Basal Cell Carcinoma Chemoprevention Trial",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Basal Cell Carcinoma"
      ],
      "interventions": [
        {
          "name": "5% Imiquimod cream",
          "type": "DRUG"
        },
        {
          "name": "Placebo Vehicle Control Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1630,
      "start_date": "2026-10-05",
      "completion_date": "2032-10-05",
      "has_results": false,
      "last_update_posted_date": "2026-09-29",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05212246"
    },
    {
      "nct_id": "NCT03680131",
      "title": "Evaluation of EB01 Cream for the Treatment of Chronic Allergic Contact Dermatitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Allergic Contact Dermatitis"
      ],
      "interventions": [
        {
          "name": "EB01 Cream Placebo",
          "type": "DRUG"
        },
        {
          "name": "EB01 Cream 0.2%",
          "type": "DRUG"
        },
        {
          "name": "EB01 Cream 1.0%",
          "type": "DRUG"
        },
        {
          "name": "EB01 Cream 2.0%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Edesa Biotech Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 211,
      "start_date": "2019-10-15",
      "completion_date": "2023-01-17",
      "has_results": false,
      "last_update_posted_date": "2024-11-14",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 14,
      "location_summary": "Long Beach, California • Washington D.C., District of Columbia • Delray Beach, Florida + 11 more",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Delray Beach",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Plainfield",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03680131"
    },
    {
      "nct_id": "NCT04211389",
      "title": "Twin Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Plaque Psoriasis"
      ],
      "interventions": [
        {
          "name": "ARQ-151 0.3% cream",
          "type": "DRUG"
        },
        {
          "name": "ARQ-151 vehicle cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Arcutis Biotherapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 442,
      "start_date": "2019-12-17",
      "completion_date": "2020-11-23",
      "has_results": true,
      "last_update_posted_date": "2022-12-07",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 31,
      "location_summary": "Scottsdale, Arizona • Beverly Hills, California • Encino, California + 26 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Encino",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04211389"
    },
    {
      "nct_id": "NCT00121381",
      "title": "Pimecrolimus Cream 1% Plus Topical Corticosteroid in Patients (2-17 Years of Age) With Severe Atopic Dermatitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dermatitis, Atopic"
      ],
      "interventions": [
        {
          "name": "Pimecrolimus plus topical corticosteroid (TCS)",
          "type": "DRUG"
        },
        {
          "name": "Pimecrolimus vehicle (Placebo) plus topical corticosteroid (TCS)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Years to 17 Years"
      },
      "enrollment_count": 400,
      "start_date": "2005-05",
      "completion_date": "2007-01",
      "has_results": false,
      "last_update_posted_date": "2008-01-15",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 13,
      "location_summary": "Huntington Beach, California • San Diego, California • Denver, Colorado + 10 more",
      "locations": [
        {
          "city": "Huntington Beach",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00121381"
    },
    {
      "nct_id": "NCT02633813",
      "title": "BE Study of Naftifine HCL",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tinea Pedis"
      ],
      "interventions": [
        {
          "name": "Naftifine hydrochloride 2%",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Naftin® 2% (Naftifine hydrochloride 2%)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Genzum Life Sciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 693,
      "start_date": "2015-03",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2017-05-11",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 12,
      "location_summary": "Brandon, Florida • Miami, Florida • Miramar, Florida + 6 more",
      "locations": [
        {
          "city": "Brandon",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miramar",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02633813"
    },
    {
      "nct_id": "NCT02427724",
      "title": "The Effect of Topical Anesthetics on Patients' Pain and Operative Experience During Treatment With QSwitched Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Lentigo"
      ],
      "interventions": [
        {
          "name": "lidocaine 2.5%/prilocaine 2.5% topical anesthetic",
          "type": "DRUG"
        },
        {
          "name": "lidocaine 7%/tetracaine 7% topical anesthetic",
          "type": "DRUG"
        },
        {
          "name": "placebo vehicle",
          "type": "DRUG"
        },
        {
          "name": "Q-switched 532nm Laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 65 Years · Female only"
      },
      "enrollment_count": 48,
      "start_date": "2015-04",
      "completion_date": "2024-05-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-10-10T22:00:36.339Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02427724"
    }
  ]
}