{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vehicle+topical+ocular%2C+eye+drops&page=2", "query": { "intervention": "Vehicle topical ocular, eye drops", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 84, "total_pages": 9, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vehicle+topical+ocular%2C+eye+drops&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Vehicle+topical+ocular%2C+eye+drops&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-06T08:20:18.140Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04499248", "title": "AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Open-angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "AGN-193408 SR", "type": "DRUG" }, { "name": "Lumigan", "type": "OTHER" }, { "name": "Sham Administration", "type": "OTHER" }, { "name": "Lumigan Vehicle", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2020-11-16", "completion_date": "2029-04", "has_results": false, "last_update_posted_date": "2026-05-22", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 42, "location_summary": "Sun City, Arizona • Glendale, California • Inglewood, California + 38 more", "locations": [ { "city": "Sun City", "state": "Arizona" }, { "city": "Glendale", "state": "California" }, { "city": "Inglewood", "state": "California" }, { "city": "Irvine", "state": "California" }, { "city": "Newport Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04499248" }, { "nct_id": "NCT02653391", "title": "A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Fuchs' Corneal Endothelial Dystrophy (FCED)" ], "interventions": [ { "name": "Part A Elamipretide 1.0% Ophthalmic Solution", "type": "DRUG" }, { "name": "Part B Elamipretide 3.0% Ophthalmic Solution", "type": "DRUG" }, { "name": "Part A Placebo", "type": "DRUG" }, { "name": "Part B Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stealth BioTherapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 22, "start_date": "2016-02", "completion_date": "2018-12", "has_results": true, "last_update_posted_date": "2021-09-17", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 2, "location_summary": "Edgewood, Kentucky • Boston, Massachusetts", "locations": [ { "city": "Edgewood", "state": "Kentucky" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02653391" }, { "nct_id": "NCT07619482", "title": "Topical Insulin for Glaucoma (TING2)", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Open Angle Glaucoma", "Primary Open Angle Glaucoma", "Low Tension Glaucoma", "Pigmentary Glaucoma", "Pseudoexfoliation Glaucoma" ], "interventions": [ { "name": "EYED-002 Low Dose (721 U/mL topical insulin)", "type": "DRUG" }, { "name": "EYED-002 High Dose (1442 U/mL topical insulin)", "type": "DRUG" }, { "name": "EYED-002 (highest tolerated dose, 12-month)", "type": "DRUG" }, { "name": "Vehicle Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 90, "start_date": "2026-06", "completion_date": "2029-10", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 1, "location_summary": "Palo Alto, California", "locations": [ { "city": "Palo Alto", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07619482" }, { "nct_id": "NCT04030962", "title": "A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Dry Eye Disease", "Dry Eye Syndrome" ], "interventions": [ { "name": "AGN-242428", "type": "DRUG" }, { "name": "AGN-231868", "type": "DRUG" }, { "name": "AGN-242428 Vehicle", "type": "OTHER" }, { "name": "AGN-231868 Vehicle", "type": "OTHER" }, { "name": "Lifitegrast 5% Ophthalmic Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 292, "start_date": "2020-03-04", "completion_date": "2022-03-18", "has_results": true, "last_update_posted_date": "2025-05-20", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 11, "location_summary": "Phoenix, Arizona • Newport Beach, California • Colorado Springs, Colorado + 8 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Newport Beach", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Andover", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04030962" }, { "nct_id": "NCT02693119", "title": "A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Leber's Hereditary Optic Neuropathy" ], "interventions": [ { "name": "elamipretide (MTP-131) 1% topical ophthalmic solution", "type": "DRUG" }, { "name": "Vehicle topical ophthalmic solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stealth BioTherapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 12, "start_date": "2016-03", "completion_date": "2019-12", "has_results": true, "last_update_posted_date": "2021-11-30", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 1, "location_summary": "Pasadena, California", "locations": [ { "city": "Pasadena", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02693119" }, { "nct_id": "NCT01060072", "title": "Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Inflammation", "Pain" ], "interventions": [ { "name": "Loteprednol etabonate", "type": "DRUG" }, { "name": "Vehicle of Loteprednol Etabonate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 407, "start_date": "2010-02", "completion_date": "2010-10", "has_results": true, "last_update_posted_date": "2012-01-13", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01060072" }, { "nct_id": "NCT03414645", "title": "Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Dry Eye", "Graft-versus-host-disease", "Ocular Discomfort" ], "interventions": [ { "name": "CAM-101 10%", "type": "BIOLOGICAL" }, { "name": "Vehicle Control", "type": "BIOLOGICAL" }, { "name": "CAM-101 30%", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Cambium Bio Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 64, "start_date": "2018-05-01", "completion_date": "2020-02-20", "has_results": true, "last_update_posted_date": "2026-06-12", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 6, "location_summary": "Palo Alto, California • Boston, Massachusetts • Ann Arbor, Michigan + 3 more", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03414645" }, { "nct_id": "NCT01998802", "title": "Phase 3 Study of EBI-005 in Dry Eye Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Dry Eye Disease (DED)" ], "interventions": [ { "name": "Active Comparator EBI-005", "type": "DRUG" }, { "name": "Placebo Comparator", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eleven Biotherapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 670, "start_date": "2014-01", "completion_date": "2015-04", "has_results": false, "last_update_posted_date": "2015-06-11", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 45, "location_summary": "Chandler, Arizona • Mesa, Arizona • Little Rock, Arkansas + 38 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Artesia", "state": "California" }, { "city": "Mission Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01998802" }, { "nct_id": "NCT04498182", "title": "A Phase 2b Study Evaluating the Safety and Efficacy of AR-15512 Ophthalmic Solution for the Treatment of Dry Eye Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dry Eye Disease" ], "interventions": [ { "name": "AR-15512 Ophthalmic Solution", "type": "DRUG" }, { "name": "AR-15512 Ophthalmic Solution Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aerie Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 369, "start_date": "2020-10-26", "completion_date": "2021-07-17", "has_results": true, "last_update_posted_date": "2024-08-28", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 15, "location_summary": "Phoenix, Arizona • Newport Beach, California • Colorado Springs, Colorado + 12 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Newport Beach", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Carmel", "state": "Indiana" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04498182" }, { "nct_id": "NCT03615196", "title": "Study of the Safety of USB005 in Healthy Volunteers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "USB005 (aclerastide) Ophthalmic Solution", "type": "DRUG" }, { "name": "USB005 Ophthalmic Solution Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "US Biotest, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 32, "start_date": "2018-07-25", "completion_date": "2019-04-02", "has_results": false, "last_update_posted_date": "2019-04-04", "last_synced_at": "2026-10-06T08:20:18.140Z", "location_count": 1, "location_summary": "Cypress, California", "locations": [ { "city": "Cypress", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03615196" } ] }