{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Very-low+energy+Diet+%28VLED%29",
    "query": {
      "intervention": "Very-low energy Diet (VLED)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T08:45:06.891Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05367596",
      "title": "OPTIMIzing muScle Preservation in paTients wIth Cirrhosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Compensated Cirrhosis",
        "Sarcopenia"
      ],
      "interventions": [
        {
          "name": "Continuous Energy Restriction (CER)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Alternate Day Modified Fasting (ADMF)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Group Health Education Sessions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Late Evening Snack",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physical activity",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-monitoring",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Remotely Supervised Exercise Sessions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2022-06-22",
      "completion_date": "2022-12-16",
      "has_results": false,
      "last_update_posted_date": "2023-02-09",
      "last_synced_at": "2026-09-29T08:45:06.891Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05367596"
    },
    {
      "nct_id": "NCT05860413",
      "title": "Intermittent Fasting for the Treatment of Type 2 Diabetes Mellitus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Intermittent energy restriction (IER)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Time Restricted Eating (TRE)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 57,
      "start_date": "2023-01-24",
      "completion_date": "2025-05-20",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-09-29T08:45:06.891Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05860413"
    },
    {
      "nct_id": "NCT03244722",
      "title": "Maternal Metabolic and Molecular Changes Induced by Preconception Weight Loss and Their Effects on Birth Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity; Familial",
        "Pregnancy Related"
      ],
      "interventions": [
        {
          "name": "Very-low energy Diet (VLED)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Standard of care (SOC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 147,
      "start_date": "2018-04-10",
      "completion_date": "2025-08-29",
      "has_results": true,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-09-29T08:45:06.891Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03244722"
    }
  ]
}