{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Wake&page=13",
    "query": {
      "intervention": "Wake",
      "page": 13
    },
    "page_size": 10
  },
  "pagination": {
    "page": 13,
    "page_size": 10,
    "total_count": 741,
    "total_pages": 75,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Wake&page=14&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Wake&page=12&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-20T13:05:54.777Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05345392",
      "title": "Brain, Emotions, and Mind-Wandering",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mood Disorders"
      ],
      "interventions": [
        {
          "name": "Mindfulness-Based Intervention (MBI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health and Wellness Intervention (HWI)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "11 Years to 14 Years"
      },
      "enrollment_count": 224,
      "start_date": "2022-09-23",
      "completion_date": "2027-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05345392"
    },
    {
      "nct_id": "NCT05219955",
      "title": "Caregiver Stress and Sleep Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depressive Symptoms",
        "Caregiver Burden"
      ],
      "interventions": [
        {
          "name": "Morning Action Plan Execution",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Activity Strategy-based Session with Therapist",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention-based Session with Therapist",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Advance sleep-wake time",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2022-07-15",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05219955"
    },
    {
      "nct_id": "NCT02713126",
      "title": "Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Sodium Nitrite",
          "type": "DRUG"
        },
        {
          "name": "Accelerometer",
          "type": "DEVICE"
        },
        {
          "name": "Cardiac Exercise Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Barry Borlaug",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 92,
      "start_date": "2016-09",
      "completion_date": "2022-04-12",
      "has_results": true,
      "last_update_posted_date": "2023-04-26",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02713126"
    },
    {
      "nct_id": "NCT03980340",
      "title": "Breath Biomarkers for Sleep Loss and Circadian Timing",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Shift-Work Sleep Disorder",
        "Shift Work Type Circadian Rhythm Sleep Disorder",
        "Sleep Disorders, Circadian Rhythm",
        "Sleep Disorders, Intrinsic",
        "Advanced Sleep Phase Syndrome (ASPS)",
        "Advanced Sleep Phase Syndrome",
        "Advanced Sleep Phase",
        "Delayed Sleep Phase",
        "Delayed Sleep Phase Syndrome",
        "Non-24 Hour Sleep-Wake Disorder",
        "Irregular Sleep-Wake Syndrome"
      ],
      "interventions": [
        {
          "name": "Short Nap Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No Nap Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 5,
      "start_date": "2021-01-28",
      "completion_date": "2025-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-03",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03980340"
    },
    {
      "nct_id": "NCT03223298",
      "title": "Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pain, Head",
        "Pain Syndrome",
        "Temporomandibular Disorder",
        "Myofascial Pain Syndrome",
        "Myofascial Pain"
      ],
      "interventions": [
        {
          "name": "Botulinum toxin type A",
          "type": "DRUG"
        },
        {
          "name": "0.9% Sodium Chloride Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 75,
      "start_date": "2018-08-31",
      "completion_date": "2020-03-13",
      "has_results": true,
      "last_update_posted_date": "2023-02-14",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • New York, New York",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03223298"
    },
    {
      "nct_id": "NCT02059421",
      "title": "Johrei Therapy and CBT-I in Facilitating Sleep in ICU Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disturbances in Survivors of Critical Illness"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Insomnia (CBT-I)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Johrei therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 50,
      "start_date": "2014-01",
      "completion_date": "2023-06",
      "has_results": false,
      "last_update_posted_date": "2025-04-16",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02059421"
    },
    {
      "nct_id": "NCT02658708",
      "title": "Bright Light on Fatigue in Women Being Treated for Breast Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Breast Neoplasms",
        "Breast Cancer",
        "Cancer of Breast",
        "Cancer of the Breast"
      ],
      "interventions": [
        {
          "name": "Bright blue-green light using light visor cap",
          "type": "OTHER"
        },
        {
          "name": "Dim red light using light visor cap",
          "type": "OTHER"
        },
        {
          "name": "European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Epworth Sleepiness Scale",
          "type": "OTHER"
        },
        {
          "name": "Pittsburgh Sleep Quality Index",
          "type": "OTHER"
        },
        {
          "name": "Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance",
          "type": "OTHER"
        },
        {
          "name": "Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue",
          "type": "OTHER"
        },
        {
          "name": "Digital foot candle datalogging light meter (Extech Instrument, Model SDL400)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Polysomnography (Easy Ambulatory 2 Cadwell, Kennewick, WA)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Horne-Ostberg Morningness-Eveningness Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Daily Fatigue and Sleep Log",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 19,
      "start_date": "2015-10-12",
      "completion_date": "2017-05-09",
      "has_results": false,
      "last_update_posted_date": "2017-09-25",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02658708"
    },
    {
      "nct_id": "NCT01027494",
      "title": "Topical Treatment of Acute Otitis Media Through Tympanostomy Tubes (AOMT) and Its Effect on Microbial Flora",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Otitis Media"
      ],
      "interventions": [
        {
          "name": "Ciprofloxacin 0.3% and dexamethasone 0.1% otic suspension",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "4 Years",
        "sex": "ALL",
        "summary": "6 Months to 4 Years"
      },
      "enrollment_count": 318,
      "start_date": "2009-12",
      "completion_date": "2012-11",
      "has_results": false,
      "last_update_posted_date": "2013-03-18",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01027494"
    },
    {
      "nct_id": "NCT05061992",
      "title": "A Trial to Improve Quality of Life in People With Cirrhosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Cirrhosis"
      ],
      "interventions": [
        {
          "name": "Lactulose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2021-11-10",
      "completion_date": "2022-11-01",
      "has_results": true,
      "last_update_posted_date": "2023-11-21",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05061992"
    },
    {
      "nct_id": "NCT04788953",
      "title": "Clinical Trial of Solriamfetol for Excessive Sleepiness Related to Shift Work Disorder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Excessive Sleepiness",
        "Shift-work Disorder"
      ],
      "interventions": [
        {
          "name": "Solriamfetol Oral Tablet",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Charles A. Czeisler, PhD, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 84,
      "start_date": "2021-07-21",
      "completion_date": "2024-04-19",
      "has_results": true,
      "last_update_posted_date": "2025-09-24",
      "last_synced_at": "2026-10-20T13:05:54.777Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04788953"
    }
  ]
}