{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Water+method&page=2",
    "query": {
      "intervention": "Water method",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Water+method&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T10:43:06.741Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01782014",
      "title": "Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Screening Colonoscopy"
      ],
      "interventions": [
        {
          "name": "colonoscopy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 450,
      "start_date": "2013-02",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2016-02-01",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01782014"
    },
    {
      "nct_id": "NCT01383252",
      "title": "Unsedated Colonoscopy for Colorectal Cancer Screening and Surveillance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colon Polyp"
      ],
      "interventions": [
        {
          "name": "Water infusion in lieu of air insufflation",
          "type": "PROCEDURE"
        },
        {
          "name": "Air method",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "VA Northern California Health Care System",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2010-02",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2013-06-17",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 1,
      "location_summary": "Mather, California",
      "locations": [
        {
          "city": "Mather",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01383252"
    },
    {
      "nct_id": "NCT06667479",
      "title": "Cold Water Exposure and Immune Function Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cold Water Immersion",
        "Immune Function",
        "Muscular Strength",
        "Mental Health"
      ],
      "interventions": [
        {
          "name": "Cold Water Immersion (CWI) - Cold Tub Immersion (CI)",
          "type": "OTHER"
        },
        {
          "name": "Cold Water Immersion (CWI) - Cold Shower (CS)",
          "type": "OTHER"
        },
        {
          "name": "Control Group (CO)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Northern Colorado",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 37,
      "start_date": "2024-10-10",
      "completion_date": "2026-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 1,
      "location_summary": "Greeley, Colorado",
      "locations": [
        {
          "city": "Greeley",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06667479"
    },
    {
      "nct_id": "NCT00715741",
      "title": "Does High Intraoperative Inspired Oxygen Reduce Postoperative Arterial Oxygen Saturation?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Atelectasis"
      ],
      "interventions": [
        {
          "name": "FiO2 (fraction of inspired oxygen) 0.3 plus PEEP (positive end expiratory pressure) 3 -5 cm water",
          "type": "OTHER"
        },
        {
          "name": "FiO2 0.3 without PEEP",
          "type": "OTHER"
        },
        {
          "name": "FiO2 >0.9 with 3-5 cm water PEEP",
          "type": "OTHER"
        },
        {
          "name": "FiO2 >0.9 without PEEP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 100,
      "start_date": "2008-06",
      "completion_date": "2009-07",
      "has_results": true,
      "last_update_posted_date": "2010-02-18",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00715741"
    },
    {
      "nct_id": "NCT02995369",
      "title": "DryShield vs Cotton Roll Isolation During Sealants Placement: Efficiency and Patient Preference",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Time",
        "Patient Preference"
      ],
      "interventions": [
        {
          "name": "DryShield",
          "type": "DEVICE"
        },
        {
          "name": "Cotton rolls",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "5 Years to 14 Years"
      },
      "enrollment_count": 32,
      "start_date": "2017-01-17",
      "completion_date": "2017-03-23",
      "has_results": true,
      "last_update_posted_date": "2023-01-20",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02995369"
    },
    {
      "nct_id": "NCT03093090",
      "title": "Evaluating Predictive Methods & Product Performance in Healthy Adults for Pediatric Patients, A Case Study: Furosemide",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Medication Absorption"
      ],
      "interventions": [
        {
          "name": "Water",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Parmalat™ Whole Milk",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Similac Pro-Advance™",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Ensure Plus™",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Furosemide 20 MG",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-12-31",
      "completion_date": "2019-06-01",
      "has_results": false,
      "last_update_posted_date": "2019-01-18",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03093090"
    },
    {
      "nct_id": "NCT02463487",
      "title": "Negative Pressure Wound Therapy as a Drug Delivery System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "Cardinal Pro +Simultaneous Irrigation (NPWTi)",
          "type": "DEVICE"
        },
        {
          "name": "Cardinal Pro (NPWT) Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "21 Years to 89 Years"
      },
      "enrollment_count": 150,
      "start_date": "2015-06-02",
      "completion_date": "2020-08-01",
      "has_results": true,
      "last_update_posted_date": "2023-07-24",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02463487"
    },
    {
      "nct_id": "NCT01521000",
      "title": "The Use of Bioimpedance to Determine Pre-Clinical Lymphedema in the Post-Operative Breast Cancer Patient",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Garment Sleeve",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Main Line Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2010-07",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2012-01-30",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 1,
      "location_summary": "Bryn Mawr, Pennsylvania",
      "locations": [
        {
          "city": "Bryn Mawr",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01521000"
    },
    {
      "nct_id": "NCT00227487",
      "title": "Intestinal Inflammation and Carbohydrate Digestion in Autistic Children",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism",
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "Stool collection",
          "type": "OTHER"
        },
        {
          "name": "Administration of carbohydrate solution during clinically indicated endoscopy",
          "type": "OTHER"
        },
        {
          "name": "Questionnaires",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Months",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "18 Months to 17 Years"
      },
      "enrollment_count": 115,
      "start_date": "2005-10",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2016-09-30",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Newton, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Newton",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00227487"
    },
    {
      "nct_id": "NCT01559987",
      "title": "Dental Plaque Removal Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis",
        "Gum Disease"
      ],
      "interventions": [
        {
          "name": "Manual Toothbrush only",
          "type": "OTHER"
        },
        {
          "name": "MTB + Waterpik Ultra Water Flosser 'High'",
          "type": "OTHER"
        },
        {
          "name": "MTB + Floss (MTB+Floss)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 270,
      "start_date": "2012-02",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2018-08-31",
      "last_synced_at": "2026-09-03T10:43:06.741Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01559987"
    }
  ]
}