{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Water+method&page=4",
    "query": {
      "intervention": "Water method",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 319,
    "total_pages": 32,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Water+method&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Water+method&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-18T07:55:36.967Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06667479",
      "title": "Cold Water Exposure and Immune Function Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cold Water Immersion",
        "Immune Function",
        "Muscular Strength",
        "Mental Health"
      ],
      "interventions": [
        {
          "name": "Cold Water Immersion (CWI) - Cold Tub Immersion (CI)",
          "type": "OTHER"
        },
        {
          "name": "Cold Water Immersion (CWI) - Cold Shower (CS)",
          "type": "OTHER"
        },
        {
          "name": "Control Group (CO)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Northern Colorado",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 37,
      "start_date": "2024-10-10",
      "completion_date": "2026-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-10-07",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 1,
      "location_summary": "Greeley, Colorado",
      "locations": [
        {
          "city": "Greeley",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06667479"
    },
    {
      "nct_id": "NCT01450631",
      "title": "The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-operative Complications",
        "Surgical Site Infection",
        "Surgical Wound Infection"
      ],
      "interventions": [
        {
          "name": "Prevena™ Incision Management System (PIMS)",
          "type": "DEVICE"
        },
        {
          "name": "Standard-of-care Dressing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "KCI USA, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 92,
      "start_date": "2012-02",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2024-10-16",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01450631"
    },
    {
      "nct_id": "NCT05169814",
      "title": "Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Open Wound",
        "Wound Heal"
      ],
      "interventions": [
        {
          "name": "Micro/nanobubble (MNB) - Irrigation",
          "type": "DRUG"
        },
        {
          "name": "0.9% Normal Saline - Irrigation",
          "type": "OTHER"
        },
        {
          "name": "Micro/nanobubble (MNB) - Negative Pressure Wound Therapy with Instillation (NPWTi)",
          "type": "DRUG"
        },
        {
          "name": "0.9% Normal Saline - Negative Pressure Wound Therapy with Instillation (NPWTi)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2021-10-09",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-02",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05169814"
    },
    {
      "nct_id": "NCT03511053",
      "title": "Epidural Lavage Study for Lumbar Stenosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Spinal Stenosis"
      ],
      "interventions": [
        {
          "name": "Epidural Steroid Injection with Lavage",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Dallas VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2017-12-19",
      "completion_date": "2018-07-26",
      "has_results": true,
      "last_update_posted_date": "2021-05-27",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03511053"
    },
    {
      "nct_id": "NCT01962454",
      "title": "A Study to Evaluate a Skeletal-muscle Microbiopsy Technique With Dynamic Proteomic Measurement in Healthy Male Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cachexia"
      ],
      "interventions": [
        {
          "name": "Deuterated Water",
          "type": "DRUG"
        },
        {
          "name": "Testosterone enanthate",
          "type": "DRUG"
        },
        {
          "name": "Placebo to match testosterone enanthate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "75 Years",
        "sex": "MALE",
        "summary": "60 Years to 75 Years · Male only"
      },
      "enrollment_count": 20,
      "start_date": "2014-05-05",
      "completion_date": "2015-03-20",
      "has_results": false,
      "last_update_posted_date": "2017-05-09",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01962454"
    },
    {
      "nct_id": "NCT01217385",
      "title": "Monitoring and Predicting Chemotherapy Response Using DOSI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "DOSI",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "American College of Radiology Imaging Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2011-06",
      "completion_date": "2014-10-06",
      "has_results": true,
      "last_update_posted_date": "2023-01-17",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 2,
      "location_summary": "Irvine, California • Lebanon, New Hampshire",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01217385"
    },
    {
      "nct_id": "NCT04060966",
      "title": "Neural Mechanisms of Cost and Benefit Integration During Decision-Making, Aim 2: Acute & Lifetime Stress",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Cold-Pressor Task (CPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control CPT",
          "type": "BEHAVIORAL"
        },
        {
          "name": "fMRI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 397,
      "start_date": "2019-05-01",
      "completion_date": "2022-08-01",
      "has_results": false,
      "last_update_posted_date": "2023-07-25",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04060966"
    },
    {
      "nct_id": "NCT00633854",
      "title": "High-frequency-ultrasound Annular Arrays for Ophthalmic Imaging",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Posterior Vitreous Detachment"
      ],
      "interventions": [
        {
          "name": "Ultrasound examination",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 30,
      "start_date": "2008-02",
      "completion_date": "2010-04-30",
      "has_results": false,
      "last_update_posted_date": "2019-03-28",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00633854"
    },
    {
      "nct_id": "NCT06182319",
      "title": "Optimizing Treatment of Adhesive Small Bowel Obstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Adhesive Small Bowel Obstruction"
      ],
      "interventions": [
        {
          "name": "Gastrografin",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        },
        {
          "name": "SBO Treatment Without NG Tubes",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2024-01-01",
      "completion_date": "2025-12-15",
      "has_results": false,
      "last_update_posted_date": "2024-05-08",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06182319"
    },
    {
      "nct_id": "NCT07840521",
      "title": "Investigating Near-Threshold Perception During Ultrasonic Deep Brain Stimulation",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Consciousness, Level Altered"
      ],
      "interventions": [
        {
          "name": "Low-intensity focused ultrasound pulsation (LIFUP)",
          "type": "DEVICE"
        },
        {
          "name": "Functional Magnetic Resonance Imaging (fMRI)",
          "type": "DEVICE"
        },
        {
          "name": "Magnetic Resonance Spectroscopy",
          "type": "DEVICE"
        },
        {
          "name": "Multi-modal glymphatic function MRI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 90,
      "start_date": "2026-11-30",
      "completion_date": "2032-03",
      "has_results": false,
      "last_update_posted_date": "2026-10-13",
      "last_synced_at": "2026-10-18T07:55:36.967Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07840521"
    }
  ]
}