{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=WaveLight+Wavefront+Optimized",
    "query": {
      "intervention": "WaveLight Wavefront Optimized"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T12:45:33.390Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01138189",
      "title": "Wavefront-guided Versus Wavefront-optimized LASIK for Nearsightedness",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Wavefront-guided LASIK",
          "type": "PROCEDURE"
        },
        {
          "name": "Wavefront-optimized LASIK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Edward E. Manche",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2010-04-06",
      "completion_date": "2012-04-30",
      "has_results": false,
      "last_update_posted_date": "2021-12-08",
      "last_synced_at": "2026-09-03T12:45:33.390Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01138189"
    },
    {
      "nct_id": "NCT00821236",
      "title": "Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Excimer Laser",
          "type": "DEVICE"
        },
        {
          "name": "AMO/VISX CustomVue™",
          "type": "DEVICE"
        },
        {
          "name": "LADARVision 4000 excimer laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Durrie Vision",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2009-01",
      "completion_date": "2010-02",
      "has_results": true,
      "last_update_posted_date": "2013-03-01",
      "last_synced_at": "2026-09-03T12:45:33.390Z",
      "location_count": 2,
      "location_summary": "Overland Park, Kansas • Greensboro, North Carolina",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        },
        {
          "city": "Greensboro",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00821236"
    },
    {
      "nct_id": "NCT02091934",
      "title": "Wavefront-guided PRK vs Wavefront-optimized PRK",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Wavefront-guided PRK",
          "type": "PROCEDURE"
        },
        {
          "name": "Wavefront-optimized PRK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 71,
      "start_date": "2009-04-01",
      "completion_date": "2012-03-31",
      "has_results": false,
      "last_update_posted_date": "2021-12-08",
      "last_synced_at": "2026-09-03T12:45:33.390Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02091934"
    },
    {
      "nct_id": "NCT05486546",
      "title": "Contoura With Phorcides Compared to Wavefront Optimized LASIK",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Contoura with Phorcides",
          "type": "PROCEDURE"
        },
        {
          "name": "WaveLight Wavefront Optimized",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Daniel Terveen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "38 Years",
        "sex": "ALL",
        "summary": "21 Years to 38 Years"
      },
      "enrollment_count": 120,
      "start_date": "2022-08-15",
      "completion_date": "2023-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-04-26",
      "last_synced_at": "2026-09-03T12:45:33.390Z",
      "location_count": 4,
      "location_summary": "Bozeman, Montana • Omaha, Nebraska • Fargo, North Dakota + 1 more",
      "locations": [
        {
          "city": "Bozeman",
          "state": "Montana"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Fargo",
          "state": "North Dakota"
        },
        {
          "city": "Sioux Falls",
          "state": "South Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05486546"
    },
    {
      "nct_id": "NCT01746589",
      "title": "Visual Outcomes and Contrast Sensitivity After Myopic LASIK",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "bilateral myopic LASIK",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Daniel S. Durrie, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2011-11",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2013-01-28",
      "last_synced_at": "2026-09-03T12:45:33.390Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01746589"
    },
    {
      "nct_id": "NCT02565537",
      "title": "High Resolution Wavefront-guided vs. Wavefront Optimized LASIK",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nearsightedness",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "LASIK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 100,
      "start_date": "2015-10",
      "completion_date": "2025-04-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-24",
      "last_synced_at": "2026-09-03T12:45:33.390Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02565537"
    },
    {
      "nct_id": "NCT04805593",
      "title": "Clinical Investigation of the WaveLight® EX500 Excimer Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperopia",
        "Hyperopic Astigmatism"
      ],
      "interventions": [
        {
          "name": "WaveLight EX500 excimer laser system",
          "type": "DEVICE"
        },
        {
          "name": "LASIK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2021-04-28",
      "completion_date": "2023-05-02",
      "has_results": true,
      "last_update_posted_date": "2024-08-21",
      "last_synced_at": "2026-09-03T12:45:33.390Z",
      "location_count": 5,
      "location_summary": "Overland Park, Kansas • Kansas City, Missouri • Greensboro, North Carolina + 2 more",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "Greensboro",
          "state": "North Carolina"
        },
        {
          "city": "West Fargo",
          "state": "North Dakota"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04805593"
    },
    {
      "nct_id": "NCT07201298",
      "title": "A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Ray-Tracing Guided LASIK",
          "type": "DEVICE"
        },
        {
          "name": "Keratorefractive Lenticule Extraction (KLEx)",
          "type": "DEVICE"
        },
        {
          "name": "WaveFront Optimized LASIK",
          "type": "DEVICE"
        },
        {
          "name": "Topography Guided LASIK",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Hoopes Vision",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "22 Years to 50 Years"
      },
      "enrollment_count": 120,
      "start_date": "2025-09",
      "completion_date": "2029-09",
      "has_results": false,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-09-03T12:45:33.390Z",
      "location_count": 1,
      "location_summary": "Draper, Utah",
      "locations": [
        {
          "city": "Draper",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07201298"
    },
    {
      "nct_id": "NCT00770094",
      "title": "Multi Laser Platform Comparison Study for LASIK",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Excimer Lasers",
          "type": "DEVICE"
        },
        {
          "name": "Excimer Laser for the LASIK procedure",
          "type": "DEVICE"
        },
        {
          "name": "Excimer Laser for LASIK",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Durrie Vision",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2008-10",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2009-08-06",
      "last_synced_at": "2026-09-03T12:45:33.390Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Edina, Minnesota • McLean, Virginia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Edina",
          "state": "Minnesota"
        },
        {
          "city": "McLean",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00770094"
    }
  ]
}