{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Wavefront+optimized+LASIK",
    "query": {
      "intervention": "Wavefront optimized LASIK"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Wavefront+optimized+LASIK&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T10:42:21.811Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01135719",
      "title": "A Comparison of Fellow Eyes Undergoing LASIK or PRK With a Wavefront-guided Excimer Laser Versus a Wavefront-optimized Excimer Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperopia",
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "LASIK and PRK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Edward E. Manche",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 137,
      "start_date": "2009-04",
      "completion_date": "2022-12-03",
      "has_results": false,
      "last_update_posted_date": "2022-12-07",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01135719"
    },
    {
      "nct_id": "NCT07126756",
      "title": "LASIK iDesign vs SMILE",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "STAR S4 IR Excimer Laser System",
          "type": "DEVICE"
        },
        {
          "name": "VisuMax 400 Surgical Laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "59th Medical Wing",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 57,
      "start_date": "2024-06-10",
      "completion_date": "2026-01-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-17",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 1,
      "location_summary": "Lackland Air Force Base, Texas",
      "locations": [
        {
          "city": "Lackland Air Force Base",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07126756"
    },
    {
      "nct_id": "NCT01138189",
      "title": "Wavefront-guided Versus Wavefront-optimized LASIK for Nearsightedness",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Wavefront-guided LASIK",
          "type": "PROCEDURE"
        },
        {
          "name": "Wavefront-optimized LASIK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Edward E. Manche",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2010-04-06",
      "completion_date": "2012-04-30",
      "has_results": false,
      "last_update_posted_date": "2021-12-08",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01138189"
    },
    {
      "nct_id": "NCT05037370",
      "title": "CONTOURA vs WFO Ablation PRK & LASIK",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Surgery"
      ],
      "interventions": [
        {
          "name": "Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "59th Medical Wing",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 400,
      "start_date": "2021-04-22",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05037370"
    },
    {
      "nct_id": "NCT01097525",
      "title": "Optical Quality, Threshold Target Identification, and Military Target Task Performance After Advanced Keratorefractive Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Myopic Astigmatism"
      ],
      "interventions": [
        {
          "name": "WFG PRK",
          "type": "PROCEDURE"
        },
        {
          "name": "WFG LASIK",
          "type": "PROCEDURE"
        },
        {
          "name": "WFO PRK",
          "type": "PROCEDURE"
        },
        {
          "name": "WFO LASIK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Fort Belvoir Community Hospital",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 224,
      "start_date": "2010-04",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2015-03-13",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • Fort Belvoir, Virginia",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Fort Belvoir",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01097525"
    },
    {
      "nct_id": "NCT00821236",
      "title": "Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Excimer Laser",
          "type": "DEVICE"
        },
        {
          "name": "AMO/VISX CustomVue™",
          "type": "DEVICE"
        },
        {
          "name": "LADARVision 4000 excimer laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Durrie Vision",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2009-01",
      "completion_date": "2010-02",
      "has_results": true,
      "last_update_posted_date": "2013-03-01",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 2,
      "location_summary": "Overland Park, Kansas • Greensboro, North Carolina",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        },
        {
          "city": "Greensboro",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00821236"
    },
    {
      "nct_id": "NCT01746589",
      "title": "Visual Outcomes and Contrast Sensitivity After Myopic LASIK",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "bilateral myopic LASIK",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Daniel S. Durrie, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2011-11",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2013-01-28",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01746589"
    },
    {
      "nct_id": "NCT05486546",
      "title": "Contoura With Phorcides Compared to Wavefront Optimized LASIK",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Contoura with Phorcides",
          "type": "PROCEDURE"
        },
        {
          "name": "WaveLight Wavefront Optimized",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Daniel Terveen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "38 Years",
        "sex": "ALL",
        "summary": "21 Years to 38 Years"
      },
      "enrollment_count": 120,
      "start_date": "2022-08-15",
      "completion_date": "2023-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-04-26",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 4,
      "location_summary": "Bozeman, Montana • Omaha, Nebraska • Fargo, North Dakota + 1 more",
      "locations": [
        {
          "city": "Bozeman",
          "state": "Montana"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Fargo",
          "state": "North Dakota"
        },
        {
          "city": "Sioux Falls",
          "state": "South Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05486546"
    },
    {
      "nct_id": "NCT00770094",
      "title": "Multi Laser Platform Comparison Study for LASIK",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Excimer Lasers",
          "type": "DEVICE"
        },
        {
          "name": "Excimer Laser for the LASIK procedure",
          "type": "DEVICE"
        },
        {
          "name": "Excimer Laser for LASIK",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Durrie Vision",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2008-10",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2009-08-06",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Edina, Minnesota • McLean, Virginia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Edina",
          "state": "Minnesota"
        },
        {
          "city": "McLean",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00770094"
    },
    {
      "nct_id": "NCT03075176",
      "title": "Topo-guided LASIK and Photorefractive Keratectomy vs Wavefront LASIK and Photorefractive Keratectomy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgery",
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Wavefront optimized LASIK",
          "type": "DEVICE"
        },
        {
          "name": "Wavefront optimized Photorefractive Keratectomy",
          "type": "DEVICE"
        },
        {
          "name": "Topography-guided LASIK",
          "type": "DEVICE"
        },
        {
          "name": "Topography-guided Photorefractive Keratectomy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2017-02-13",
      "completion_date": "2019-08-12",
      "has_results": true,
      "last_update_posted_date": "2023-07-17",
      "last_synced_at": "2026-09-03T10:42:21.811Z",
      "location_count": 1,
      "location_summary": "Murray, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03075176"
    }
  ]
}