{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Wavefront-guided+PRK",
    "query": {
      "intervention": "Wavefront-guided PRK"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T02:34:18.009Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05037370",
      "title": "CONTOURA vs WFO Ablation PRK & LASIK",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Surgery"
      ],
      "interventions": [
        {
          "name": "Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "59th Medical Wing",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 400,
      "start_date": "2021-04-22",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-09-07T02:34:18.009Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05037370"
    },
    {
      "nct_id": "NCT01140594",
      "title": "Wavefront-guided Photorefractive Keratectomy (PRK) Versus Wavefront-guided Lasik for Myopia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Photorefractive keratectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Laser in-situ keratomileusis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2006-08",
      "completion_date": "2008-01",
      "has_results": false,
      "last_update_posted_date": "2022-04-11",
      "last_synced_at": "2026-09-07T02:34:18.009Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01140594"
    },
    {
      "nct_id": "NCT02091934",
      "title": "Wavefront-guided PRK vs Wavefront-optimized PRK",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Wavefront-guided PRK",
          "type": "PROCEDURE"
        },
        {
          "name": "Wavefront-optimized PRK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 71,
      "start_date": "2009-04-01",
      "completion_date": "2012-03-31",
      "has_results": false,
      "last_update_posted_date": "2021-12-08",
      "last_synced_at": "2026-09-07T02:34:18.009Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02091934"
    },
    {
      "nct_id": "NCT01097525",
      "title": "Optical Quality, Threshold Target Identification, and Military Target Task Performance After Advanced Keratorefractive Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Myopic Astigmatism"
      ],
      "interventions": [
        {
          "name": "WFG PRK",
          "type": "PROCEDURE"
        },
        {
          "name": "WFG LASIK",
          "type": "PROCEDURE"
        },
        {
          "name": "WFO PRK",
          "type": "PROCEDURE"
        },
        {
          "name": "WFO LASIK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Fort Belvoir Community Hospital",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 224,
      "start_date": "2010-04",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2015-03-13",
      "last_synced_at": "2026-09-07T02:34:18.009Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • Fort Belvoir, Virginia",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Fort Belvoir",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01097525"
    },
    {
      "nct_id": "NCT00412295",
      "title": "Evaluation of Alcon Ladarvision Wavefront-Guided PRK",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Alcon Ladarvision (Wavefront-guided PRK)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Walter Reed Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 0,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2025-07-23",
      "last_synced_at": "2026-09-07T02:34:18.009Z",
      "location_count": 2,
      "location_summary": "San Diego, California • Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00412295"
    },
    {
      "nct_id": "NCT03075176",
      "title": "Topo-guided LASIK and Photorefractive Keratectomy vs Wavefront LASIK and Photorefractive Keratectomy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgery",
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Wavefront optimized LASIK",
          "type": "DEVICE"
        },
        {
          "name": "Wavefront optimized Photorefractive Keratectomy",
          "type": "DEVICE"
        },
        {
          "name": "Topography-guided LASIK",
          "type": "DEVICE"
        },
        {
          "name": "Topography-guided Photorefractive Keratectomy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2017-02-13",
      "completion_date": "2019-08-12",
      "has_results": true,
      "last_update_posted_date": "2023-07-17",
      "last_synced_at": "2026-09-07T02:34:18.009Z",
      "location_count": 1,
      "location_summary": "Murray, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03075176"
    },
    {
      "nct_id": "NCT01135719",
      "title": "A Comparison of Fellow Eyes Undergoing LASIK or PRK With a Wavefront-guided Excimer Laser Versus a Wavefront-optimized Excimer Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperopia",
        "Myopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "LASIK and PRK",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Edward E. Manche",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 137,
      "start_date": "2009-04",
      "completion_date": "2022-12-03",
      "has_results": false,
      "last_update_posted_date": "2022-12-07",
      "last_synced_at": "2026-09-07T02:34:18.009Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01135719"
    }
  ]
}