{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Wound+closure+matrix+application",
    "query": {
      "intervention": "Wound closure matrix application"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Wound+closure+matrix+application&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T05:26:30.911Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07632001",
      "title": "Miro3D Wound Matrix for Treatment of Diabetic Foot Ulcers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcers (DFUs)",
        "Diabetic Foot",
        "Chronic Wounds"
      ],
      "interventions": [
        {
          "name": "Miro3D Wound Matrix",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Reprise Biomedical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2026-06-15",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-08-13",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 14,
      "location_summary": "Phoenix, Arizona • Coconut Creek, Florida • Coral Gables, Florida + 9 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Coconut Creek",
          "state": "Florida"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Tamarac",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07632001"
    },
    {
      "nct_id": "NCT06939673",
      "title": "Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcers (DFUs)",
        "Venous Leg Ulcers (VLUs)",
        "Pressure Ulcers",
        "Surgical Wound Dehiscence (SWD)",
        "Chronic Wounds",
        "Undermined and Tunneling Wounds"
      ],
      "interventions": [
        {
          "name": "Acellular Porcine-Derived Wound Matrix",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Reprise Biomedical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2024-02-29",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 2,
      "location_summary": "Coconut Creek, Florida • Tamarac, Florida",
      "locations": [
        {
          "city": "Coconut Creek",
          "state": "Florida"
        },
        {
          "city": "Tamarac",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06939673"
    },
    {
      "nct_id": "NCT07385313",
      "title": "Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Soft Tissue Defects",
        "Soft Tissue Wounds",
        "Traumatic Soft Tissue Defect"
      ],
      "interventions": [
        {
          "name": "Myriad™ applied in conjunction with NPWT",
          "type": "DEVICE"
        },
        {
          "name": "NPWT Alone",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Aroa Biosurgery Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2026-03-31",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado • San Antonio, Texas",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07385313"
    },
    {
      "nct_id": "NCT06035523",
      "title": "Clinical Study Evaluating Wound Closure With Endoform™ and Symphony™",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wound Healing",
        "Diabetic Foot",
        "Chronic Foot Ulcer",
        "Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "Endoform™ Antibacterial",
          "type": "DEVICE"
        },
        {
          "name": "Endoform™ Natural",
          "type": "DEVICE"
        },
        {
          "name": "Symphony™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Aroa Biosurgery Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2021-12-29",
      "completion_date": "2025-08-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 4,
      "location_summary": "Hollywood, Florida • Miami, Florida • Salem, Virginia + 1 more",
      "locations": [
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Salem",
          "state": "Virginia"
        },
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06035523"
    },
    {
      "nct_id": "NCT06035536",
      "title": "Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot",
        "Diabetic Foot Ulcer",
        "Foot Ulcer",
        "Chronic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "Symphony™ plus Off-loading",
          "type": "DEVICE"
        },
        {
          "name": "Wound Dressing comprising of calcium alginate Fibracol",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Aroa Biosurgery Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 143,
      "start_date": "2023-06-08",
      "completion_date": "2025-11-03",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 11,
      "location_summary": "Los Angeles, California • San Francisco, California • Miami, Florida + 7 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Tamarac",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06035536"
    },
    {
      "nct_id": "NCT06028386",
      "title": "Use of AC5® Advanced Wound System in the Treatment of Diabetic Foot Ulcers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-healing Wound",
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "AC5® Advanced Wound System",
          "type": "DEVICE"
        },
        {
          "name": "Fibracol Plus Collagen Dressing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Arch Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-08-15",
      "completion_date": "2024-08-30",
      "has_results": false,
      "last_update_posted_date": "2023-09-11",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 2,
      "location_summary": "Greenville, North Carolina • Circleville, Ohio",
      "locations": [
        {
          "city": "Greenville",
          "state": "North Carolina"
        },
        {
          "city": "Circleville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06028386"
    },
    {
      "nct_id": "NCT07321704",
      "title": "Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pilonidal Disease"
      ],
      "interventions": [
        {
          "name": "Irrisept (0.05% chlorhexidine gluconate)",
          "type": "DEVICE"
        },
        {
          "name": "Normal Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Yosef Nasseri, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-02-17",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07321704"
    },
    {
      "nct_id": "NCT07086443",
      "title": "Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "DFU",
        "Diabetic Foot Ulcer (DFU)",
        "Foot Ulcer Due to Type 1 Diabetes Mellitus",
        "Foot Ulcer Due to Type 2 Diabetes Mellitus",
        "Ulcer",
        "Ulcer Foot"
      ],
      "interventions": [
        {
          "name": "Activate™ Matrix",
          "type": "OTHER"
        },
        {
          "name": "AmnioDefend™ FT Matrix",
          "type": "OTHER"
        },
        {
          "name": "Palisade™ DM Matrix",
          "type": "OTHER"
        },
        {
          "name": "Enclose™ TL Matrix",
          "type": "OTHER"
        },
        {
          "name": "Sentry™ SL Matrix",
          "type": "OTHER"
        },
        {
          "name": "Shelter™ DM Matrix + SOC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Sequence LifeScience, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 350,
      "start_date": "2025-07-11",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 1,
      "location_summary": "Monroeville, Pennsylvania",
      "locations": [
        {
          "city": "Monroeville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07086443"
    },
    {
      "nct_id": "NCT06073808",
      "title": "The Role of Amnion Membrane Allografts in Nipple Preservation",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mastectomy",
        "Gender Affirmation Surgery",
        "Nipple Sparing Mastectomy",
        "Prophylactic Mastectomy",
        "Benign Breast Condition"
      ],
      "interventions": [
        {
          "name": "AmnioFix dehydrated Human Amnion/Chorion Membrane Allograft",
          "type": "DEVICE"
        },
        {
          "name": "Control Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "15 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-06-01",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06073808"
    },
    {
      "nct_id": "NCT07268092",
      "title": "Porcine Extracellular Matrix Nerve Wrap in Neck Dissection for Head and Neck Cancer",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Head and Neck Cancer",
        "Neck Dissection",
        "Postoperative Complications"
      ],
      "interventions": [
        {
          "name": "Porcine Extracellular Matrix Nerve Wrap (AxoGuard Nerve Protector™)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2021-01-25",
      "completion_date": "2026-08-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-05",
      "last_synced_at": "2026-09-04T05:26:30.911Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07268092"
    }
  ]
}