{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=XR-NTX+%28Extended-Release+Naltrexone%29&page=2",
    "query": {
      "intervention": "XR-NTX (Extended-Release Naltrexone)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 26,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=XR-NTX+%28Extended-Release+Naltrexone%29&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=XR-NTX+%28Extended-Release+Naltrexone%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T05:57:21.444Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03275350",
      "title": "Comparing Treatments for HIV-Infected Opioid Users in an Integrated Care Effectiveness Study (CHOICES) Scale-Up",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Opioid-use Disorder",
        "Hiv"
      ],
      "interventions": [
        {
          "name": "Naltrexone Injectable Suspension",
          "type": "DRUG"
        },
        {
          "name": "Treatment as usual",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 114,
      "start_date": "2018-02-05",
      "completion_date": "2019-11-08",
      "has_results": true,
      "last_update_posted_date": "2022-04-27",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 5,
      "location_summary": "Tarzana, California • Miami, Florida • Chicago, Illinois + 2 more",
      "locations": [
        {
          "city": "Tarzana",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03275350"
    },
    {
      "nct_id": "NCT04219540",
      "title": "Long-acting Buprenorphine vs. Naltrexone Opioid Treatments in CJS-involved Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opioid-use Disorder"
      ],
      "interventions": [
        {
          "name": "XR-B (SUBLOCADETM)",
          "type": "DRUG"
        },
        {
          "name": "XR-NTX",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 675,
      "start_date": "2021-01-07",
      "completion_date": "2025-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-05-14",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 6,
      "location_summary": "New Haven, Connecticut • Baltimore, Maryland • Hanover, New Hampshire + 3 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Hanover",
          "state": "New Hampshire"
        },
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04219540"
    },
    {
      "nct_id": "NCT01999946",
      "title": "Extended-Release Naltrexone Opioid Treatment at Jail Re-Entry",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heroin Dependence",
        "Opioid-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Extended-Release Naltrexone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 217,
      "start_date": "2014-06-27",
      "completion_date": "2020-12-24",
      "has_results": true,
      "last_update_posted_date": "2021-06-25",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01999946"
    },
    {
      "nct_id": "NCT02602795",
      "title": "Distress Tolerance and HIV Prevention With XR-NTX Initiation in Opioid Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opiate Dependence",
        "Sexually Transmitted Diseases",
        "HIV"
      ],
      "interventions": [
        {
          "name": "Acceptance and Commitment Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Information Motivation Behavioral Model",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rhode Island Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2015-12",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2018-08-29",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02602795"
    },
    {
      "nct_id": "NCT02478489",
      "title": "Alcohol Disorder hOsPital Treatment Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heavy Drinking",
        "Alcohol Dependence",
        "Alcohol Use Disorder"
      ],
      "interventions": [
        {
          "name": "Oral naltrexone (PO-NTX)",
          "type": "DRUG"
        },
        {
          "name": "Extended-release injectable naltrexone (XR-NTX)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 248,
      "start_date": "2016-06",
      "completion_date": "2020-10",
      "has_results": true,
      "last_update_posted_date": "2021-06-29",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02478489"
    },
    {
      "nct_id": "NCT03902821",
      "title": "Reducing Overdose After Release From Incarceration",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Overdose, Drug"
      ],
      "interventions": [
        {
          "name": "XR-NTX and Certified Recovery Mentor",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 100 Years · Female only"
      },
      "enrollment_count": 65,
      "start_date": "2019-06-17",
      "completion_date": "2023-11-30",
      "has_results": false,
      "last_update_posted_date": "2024-04-17",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 1,
      "location_summary": "Wilsonville, Oregon",
      "locations": [
        {
          "city": "Wilsonville",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03902821"
    },
    {
      "nct_id": "NCT01180647",
      "title": "Extended-Release Naltrexone for Opioid Relapse Prevention Following Release From Jail",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Opiate Dependence"
      ],
      "interventions": [
        {
          "name": "Extended-Release Naltrexone",
          "type": "DRUG"
        },
        {
          "name": "Motivational Enhancement Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 48,
      "start_date": "2010-05",
      "completion_date": "2013-07",
      "has_results": true,
      "last_update_posted_date": "2016-04-07",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01180647"
    },
    {
      "nct_id": "NCT06104280",
      "title": "Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Opioid Use Disorder",
        "Sleep Disturbance"
      ],
      "interventions": [
        {
          "name": "Post-Illumination Pupillary Response (PIPR)",
          "type": "OTHER"
        },
        {
          "name": "Polysomnography",
          "type": "OTHER"
        },
        {
          "name": "Multiple Sleep Latency Test",
          "type": "OTHER"
        },
        {
          "name": "Ecological Momentary Assessments",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Actigraphy",
          "type": "DEVICE"
        },
        {
          "name": "DLMO",
          "type": "OTHER"
        },
        {
          "name": "Melatonin Suppression Test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 200,
      "start_date": "2025-01-06",
      "completion_date": "2029-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-11",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06104280"
    },
    {
      "nct_id": "NCT01843023",
      "title": "Extended Release Naltrexone for Opioid-Dependent Youth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Drug Dependence"
      ],
      "interventions": [
        {
          "name": "Extended Release Naltrexone",
          "type": "DRUG"
        },
        {
          "name": "Psychosocial Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Buprenorphine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Friends Research Institute, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "15 Years to 21 Years"
      },
      "enrollment_count": 288,
      "start_date": "2013-06",
      "completion_date": "2019-07",
      "has_results": true,
      "last_update_posted_date": "2021-11-10",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01843023"
    },
    {
      "nct_id": "NCT04464980",
      "title": "Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Opioid Use Disorder (OUD)"
      ],
      "interventions": [
        {
          "name": "SL-BUP",
          "type": "DRUG"
        },
        {
          "name": "XR-BUP",
          "type": "DRUG"
        },
        {
          "name": "XR-NTX",
          "type": "DRUG"
        },
        {
          "name": "MM",
          "type": "BEHAVIORAL"
        },
        {
          "name": "MMR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "MMD",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1516,
      "start_date": "2021-06-08",
      "completion_date": "2027-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-01",
      "last_synced_at": "2026-10-06T05:57:21.444Z",
      "location_count": 21,
      "location_summary": "Little Rock, Arkansas • Tarzana, California • Bridgeport, Connecticut + 17 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Tarzana",
          "state": "California"
        },
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "Clearwater",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04464980"
    }
  ]
}