{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Xalatan", "query": { "intervention": "Xalatan" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 125, "total_pages": 13, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Xalatan&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-03T09:15:04.880Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00934089", "title": "A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma, Open-Angle", "Ocular Hypertension" ], "interventions": [ { "name": "PF-04217329", "type": "DRUG" }, { "name": "latanoprost vehicle", "type": "DRUG" }, { "name": "latanoprost", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 31, "start_date": "2010-01", "completion_date": "2010-06", "has_results": true, "last_update_posted_date": "2021-05-03", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 8, "location_summary": "Cypress, California • Garden Grove, California • Gardena, California + 4 more", "locations": [ { "city": "Cypress", "state": "California" }, { "city": "Garden Grove", "state": "California" }, { "city": "Gardena", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00934089" }, { "nct_id": "NCT05935527", "title": "Assess the Safety, Tolerability and Efficacy of Latanoprost Liposome for Lower Eyelid Steatoblepharon", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Lower Eyelid Steatoblepharon" ], "interventions": [ { "name": "POLAT-001", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Peregrine Ophthalmic", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 50, "start_date": "2023-04-28", "completion_date": "2024-11-18", "has_results": false, "last_update_posted_date": "2025-01-29", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 3, "location_summary": "Newport Beach, California • Coral Gables, Florida • Pflugerville, Texas", "locations": [ { "city": "Newport Beach", "state": "California" }, { "city": "Coral Gables", "state": "Florida" }, { "city": "Pflugerville", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05935527" }, { "nct_id": "NCT06883123", "title": "Efficacy of Simbrinza and Rocklatan vs Cosopt and Latanoprost", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Open Angle Glaucoma" ], "interventions": [ { "name": "Simbrinza 0.2%-1% Ophthalmic Suspension", "type": "DRUG" }, { "name": "Rocklatan 0.02%-0.005% Ophthalmic Solution", "type": "DRUG" }, { "name": "Cosopt PF 2%-0.5% Ophthalmic Solution", "type": "DRUG" }, { "name": "Latanoprost 0.005% Ophthalmic Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Prairie Eye Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 70, "start_date": "2025-05-14", "completion_date": "2026-04-01", "has_results": false, "last_update_posted_date": "2025-05-15", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 1, "location_summary": "Springfield, Illinois", "locations": [ { "city": "Springfield", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06883123" }, { "nct_id": "NCT00441883", "title": "Dose-Finding Study Comparing the Safety and Efficacy of Latanoprost to a Novel Treatment for Glaucoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Primary Open Angle Glaucoma", "Ocular Hypertension", "Pigmentary Glaucoma", "Pseudoexfoliative Glaucoma" ], "interventions": [ { "name": "PF-03187207 and Latanoprost Vehicle", "type": "DRUG" }, { "name": "Latanoprost 0.005% and PF-03187207 Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 176, "start_date": "2007-03", "completion_date": "2008-07", "has_results": true, "last_update_posted_date": "2020-09-14", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 19, "location_summary": "Artesia, California • Newport Beach, California • Petaluma, California + 15 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Petaluma", "state": "California" }, { "city": "Poway", "state": "California" }, { "city": "Danbury", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00441883" }, { "nct_id": "NCT01037036", "title": "A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Ocular Hypertension", "Open-Angle Glaucoma" ], "interventions": [ { "name": "Latanoprost Punctal Plug Delivery System", "type": "DRUG" }, { "name": "Xalatan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2009-12", "completion_date": "2010-07", "has_results": false, "last_update_posted_date": "2014-01-10", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 1, "location_summary": "Menlo Park, California", "locations": [ { "city": "Menlo Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01037036" }, { "nct_id": "NCT01042665", "title": "Relationship Between Eye Pressure and Ganglion Cell Function in Eyes Receiving Latanoprost Versus Placebo", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Glaucoma" ], "interventions": [ { "name": "latanoprost 0.005%", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Miami", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 82, "start_date": "2006-02", "completion_date": "2009-12", "has_results": false, "last_update_posted_date": "2014-03-28", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 1, "location_summary": "Palm Beach Gardens, Florida", "locations": [ { "city": "Palm Beach Gardens", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01042665" }, { "nct_id": "NCT03216902", "title": "A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Open-angle Glaucoma, Ocular Hypertension" ], "interventions": [ { "name": "Vehicle of DE-126 Ophthalmic Solution, high dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "Topical ultra-low dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "Topical low dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "Topical medium dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "Topical high dose of DE-126 Ophthalmic Solution", "type": "DRUG" }, { "name": "0.005% Latanoprost Ophthalmic Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Santen Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 241, "start_date": "2017-07-25", "completion_date": "2018-02-27", "has_results": true, "last_update_posted_date": "2020-10-23", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 12, "location_summary": "Artesia, California • Mission Hills, California • Newport Beach, California + 9 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Mission Hills", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Petaluma", "state": "California" }, { "city": "Largo", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03216902" }, { "nct_id": "NCT00821002", "title": "A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Open-Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Latanoprost", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 32, "start_date": "2009-01", "completion_date": "2009-11", "has_results": false, "last_update_posted_date": "2013-09-19", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 1, "location_summary": "Menlo Park, California", "locations": [ { "city": "Menlo Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00821002" }, { "nct_id": "NCT04412096", "title": "Aqueous Humor Dynamic Components That Determine Intraocular Pressure Variance", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Glaucoma", "OHT - Ocular Hypertension" ], "interventions": [ { "name": "Timolol 0.5% ophthalmic solution", "type": "DRUG" }, { "name": "Latanoprost 0.005% Ophthalmic Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ohio State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 59, "start_date": "2020-11-23", "completion_date": "2025-05-22", "has_results": false, "last_update_posted_date": "2026-03-04", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 3, "location_summary": "Rochester, Minnesota • Omaha, Nebraska • Columbus, Ohio", "locations": [ { "city": "Rochester", "state": "Minnesota" }, { "city": "Omaha", "state": "Nebraska" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04412096" }, { "nct_id": "NCT01410188", "title": "Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Primary Open-angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "OPA-6566", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Latanoprost", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kubota Vision Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 160, "start_date": "2011-09", "completion_date": "2012-10", "has_results": false, "last_update_posted_date": "2014-03-11", "last_synced_at": "2026-09-03T09:15:04.880Z", "location_count": 9, "location_summary": "Artesia, California • Glendale, California • Roswell, Georgia + 6 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Glendale", "state": "California" }, { "city": "Roswell", "state": "Georgia" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Washington", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT01410188" } ] }