{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Zeaxanthin&page=2",
    "query": {
      "intervention": "Zeaxanthin",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Zeaxanthin&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T18:57:14.554Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03983525",
      "title": "The Effect of Gojiberry Intake (Lycium Barbarium) on Macular Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Macular Pigment Optical Density"
      ],
      "interventions": [
        {
          "name": "Goji berry",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Lutein + zeaxanthin supplementation",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "45 Years to 65 Years"
      },
      "enrollment_count": 31,
      "start_date": "2019-06-10",
      "completion_date": "2020-06-15",
      "has_results": false,
      "last_update_posted_date": "2020-07-23",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03983525"
    },
    {
      "nct_id": "NCT00672230",
      "title": "Dietary Lutein and the Retinopathy of Prematurity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lactation"
      ],
      "interventions": [
        {
          "name": "Lutein supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 212,
      "start_date": "2005-08",
      "completion_date": "2009-07",
      "has_results": false,
      "last_update_posted_date": "2019-08-28",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00672230"
    },
    {
      "nct_id": "NCT01527435",
      "title": "Addition of 20mg/Day Zeaxanthin to Triple Therapy Treatment Options for Age Related Macular Degeneration (ARMD)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Exudative Age-Related Macular Degeneration"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The Retina Center of St. Louis County, PC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2011-12",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2016-04-06",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01527435"
    },
    {
      "nct_id": "NCT06270680",
      "title": "Carotenoids for Collision Athletes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Head Injury",
        "Carotenoids"
      ],
      "interventions": [
        {
          "name": "Vision Edge Pro",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2024-08-01",
      "completion_date": "2024-11-22",
      "has_results": false,
      "last_update_posted_date": "2025-03-11",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06270680"
    },
    {
      "nct_id": "NCT03959592",
      "title": "Macular Pigment and Visual Performance in Glaucoma Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Lutein, zeaxanthin and mesozeaxanthin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Felipe Medeiros, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 8,
      "start_date": "2019-08-21",
      "completion_date": "2021-11-09",
      "has_results": true,
      "last_update_posted_date": "2023-01-03",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03959592"
    },
    {
      "nct_id": "NCT05177679",
      "title": "Enhancing Children's Cognitive Function and Achievement Through Carotenoid Consumption",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Change",
        "Achievement",
        "Macular Pigmentation"
      ],
      "interventions": [
        {
          "name": "Active supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo control",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "8 Years to 10 Years"
      },
      "enrollment_count": 113,
      "start_date": "2022-06-23",
      "completion_date": "2026-07-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-27",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 1,
      "location_summary": "Urbana, Illinois",
      "locations": [
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05177679"
    },
    {
      "nct_id": "NCT01646047",
      "title": "Diabetes Visual Function Supplement Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus - Type 1",
        "Diabetes Mellitus - Type 2",
        "Non-proliferative Diabetic Retinopathy"
      ],
      "interventions": [
        {
          "name": "multi-component nutritional supplement capsules",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "multi-component dietary supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "ZeaVision, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2012-05",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2015-01-22",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 1,
      "location_summary": "Tacoma, Washington",
      "locations": [
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01646047"
    },
    {
      "nct_id": "NCT05533658",
      "title": "The Effects of VisionPure™ on Indices of Vision Health and Cognitive Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eye Health",
        "Vision",
        "Cognitive Function"
      ],
      "interventions": [
        {
          "name": "VisionPure Dietary Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Applied Science & Performance Institute",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 15,
      "start_date": "2022-08-01",
      "completion_date": "2023-02-03",
      "has_results": false,
      "last_update_posted_date": "2023-05-26",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 3,
      "location_summary": "Lutz, Florida • Tampa, Florida",
      "locations": [
        {
          "city": "Lutz",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05533658"
    },
    {
      "nct_id": "NCT03750968",
      "title": "Lutein & Zeaxanthin in Pregnancy - Carotenoid Supplementation During Pregnancy: Ocular and Systemic Effects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nutrient Deficiency",
        "Pregnancy Related"
      ],
      "interventions": [
        {
          "name": "Carotenoid Group",
          "type": "DRUG"
        },
        {
          "name": "Control Group",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Paul S. Bernstein",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 47,
      "start_date": "2019-09-26",
      "completion_date": "2022-01-31",
      "has_results": true,
      "last_update_posted_date": "2023-07-11",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03750968"
    },
    {
      "nct_id": "NCT00909090",
      "title": "Macular Pigment and Glare Disability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vision, Entoptic"
      ],
      "interventions": [
        {
          "name": "12 mg Lutein + Zeaxanthin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Visually identical placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Georgia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 109,
      "start_date": "2009-05",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2020-07-13",
      "last_synced_at": "2026-09-22T18:57:14.554Z",
      "location_count": 1,
      "location_summary": "Athens, Georgia",
      "locations": [
        {
          "city": "Athens",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00909090"
    }
  ]
}