{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=aIIV4",
    "query": {
      "intervention": "aIIV4"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T08:39:27.296Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05007041",
      "title": "Simultaneous RZV and aIIV4 Vaccination",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain",
        "Quality of Life",
        "Injection Site Reaction",
        "Adverse Drug Event"
      ],
      "interventions": [
        {
          "name": "FLUAD® Quadrivalent",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Fluzone® High-Dose Quadrivalent",
          "type": "BIOLOGICAL"
        },
        {
          "name": "SHINGRIX®",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 267,
      "start_date": "2021-09-21",
      "completion_date": "2023-06-08",
      "has_results": true,
      "last_update_posted_date": "2024-07-11",
      "last_synced_at": "2026-09-04T08:39:27.296Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland • Durham, North Carolina",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05007041"
    },
    {
      "nct_id": "NCT04576702",
      "title": "Safety and Immunogenicity of an MF59-Adjuvanted Influenza Vaccine in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Influenza",
        "Human"
      ],
      "interventions": [
        {
          "name": "Investigational aIIV4c",
          "type": "BIOLOGICAL"
        },
        {
          "name": "IIV4c",
          "type": "BIOLOGICAL"
        },
        {
          "name": "aIIV4",
          "type": "BIOLOGICAL"
        },
        {
          "name": "RIV4",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Seqirus",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 471,
      "start_date": "2020-10-08",
      "completion_date": "2021-05-24",
      "has_results": true,
      "last_update_posted_date": "2024-04-17",
      "last_synced_at": "2026-09-04T08:39:27.296Z",
      "location_count": 21,
      "location_summary": "Mobile, Alabama • Tempe, Arizona • Jacksonville, Florida + 17 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Oakland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04576702"
    },
    {
      "nct_id": "NCT06029933",
      "title": "Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Influenza",
        "Community-acquired Pneumonia",
        "Cardiovascular Events"
      ],
      "interventions": [
        {
          "name": "Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "High-Dose Quadrivalent Inactivated Influenza Vaccine (HD-IIV4)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 1500000,
      "start_date": "2023-08-17",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2026-08-05",
      "last_synced_at": "2026-09-04T08:39:27.296Z",
      "location_count": 1,
      "location_summary": "Oakland, California",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06029933"
    }
  ]
}