{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=active+heat", "query": { "intervention": "active heat" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 98, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=active+heat&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-03T04:49:21.502Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05451446", "title": "The Effect of Proprietary Water on Physiological and Perceptual Responses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hydration", "Dehydration" ], "interventions": [ { "name": "proprietary water", "type": "DIETARY_SUPPLEMENT" }, { "name": "Active comparator", "type": "OTHER" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 47, "start_date": "2022-07-15", "completion_date": "2023-04-05", "has_results": false, "last_update_posted_date": "2023-04-11", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 1, "location_summary": "Columbia, South Carolina", "locations": [ { "city": "Columbia", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05451446" }, { "nct_id": "NCT00851721", "title": "Efficacy and Safety Study of Prophylactic Versus On-Demand Treatment With Feiba NF in Subjects With Hemophilia A or B and a High Titer Inhibitor", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hemophilia A or B With Inhibitors", "Hemophilia A", "Hemophilia B" ], "interventions": [ { "name": "Factor VIII Inhibitor Bypassing Activity (nanofiltered, vapor heat-treated)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Baxalta now part of Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "4 Years to 65 Years" }, "enrollment_count": 52, "start_date": "2009-03-31", "completion_date": "2012-10-17", "has_results": true, "last_update_posted_date": "2021-05-19", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 2, "location_summary": "Chicago, Illinois • Cleveland, Ohio", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00851721" }, { "nct_id": "NCT07529353", "title": "Feasibility of 'Exercise for CAncer Patients and Healthy EAting Timeframes' .", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Breast Cancer", "Cancer Related Fatigue" ], "interventions": [ { "name": "EXCAP Exercise Program", "type": "BEHAVIORAL" }, { "name": "10-Hour Healthy Eating Timeframe (hEAT)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2026-10", "completion_date": "2028-10", "has_results": false, "last_update_posted_date": "2026-08-17", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07529353" }, { "nct_id": "NCT01454882", "title": "Measuring Free-living Energy Expenditure Using Direct Calorimetry", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Temperature", "Clothing", "Sex", "Age", "Adiposity" ], "interventions": [ { "name": "Effects of Clothing", "type": "BEHAVIORAL" }, { "name": "Effects of Temperature", "type": "BEHAVIORAL" }, { "name": "Low Physical Activity", "type": "BEHAVIORAL" }, { "name": "High Physical Activity", "type": "BEHAVIORAL" }, { "name": "Direct calorimetry and doubly labeled water", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 39, "start_date": "2012-01", "completion_date": "2016-01", "has_results": false, "last_update_posted_date": "2016-01-11", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01454882" }, { "nct_id": "NCT00627419", "title": "A Study Evaluating the Safety and Antitumor Activity of IPI-504, in Patients With Metastatic Melanoma", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Metastatic Melanoma" ], "interventions": [ { "name": "IPI-504", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Infinity Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1, "start_date": "2008-02", "completion_date": "2009-10", "has_results": false, "last_update_posted_date": "2012-12-10", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 17, "location_summary": "Tuscon, Arizona • Los Angeles, California • San Diego, California + 14 more", "locations": [ { "city": "Tuscon", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00627419" }, { "nct_id": "NCT01434979", "title": "Exertional Heat Illness: Biomarkers for Prediction and Return to Duty", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Heat Illness" ], "interventions": [], "intervention_types": [], "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 148, "start_date": "2011-07", "completion_date": "2016-02", "has_results": false, "last_update_posted_date": "2019-10-11", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01434979" }, { "nct_id": "NCT05965336", "title": "Walking Function in Diabetic Peripheral Neuropathy", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Diabetic Peripheral Neuropathy" ], "interventions": [ { "name": "Clinical Evaluation", "type": "OTHER" }, { "name": "Evaluation of Passive Ankle Stiffness", "type": "OTHER" }, { "name": "Gait Biomechanics", "type": "OTHER" }, { "name": "Gait Biofeedback", "type": "OTHER" }, { "name": "Plantar Pressure Biofeedback Gait Training", "type": "OTHER" }, { "name": "Propulsion Biofeedback Gait Training", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Florida Institute for Human and Machine Cognition", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "45 Years", "maximum_age": null, "sex": "ALL", "summary": "45 Years and older" }, "enrollment_count": 50, "start_date": "2024-12-05", "completion_date": "2027-08-31", "has_results": false, "last_update_posted_date": "2026-08-18", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 1, "location_summary": "Pensacola, Florida", "locations": [ { "city": "Pensacola", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05965336" }, { "nct_id": "NCT06224127", "title": "Treating Stress and Anxiety in Individuals With Alcohol Use Disorder (AUD)", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Anxiety Disorders", "Alcohol Use Disorder", "Stress, Psychological" ], "interventions": [ { "name": "active heat", "type": "DEVICE" }, { "name": "Active c tactile fiber stimulation", "type": "DRUG" }, { "name": "sham heat", "type": "DEVICE" }, { "name": "Sham c tactile fiber stimulation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Soovu Labs Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 36, "start_date": "2024-07-15", "completion_date": "2025-03-30", "has_results": false, "last_update_posted_date": "2024-01-25", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT06224127" }, { "nct_id": "NCT00223717", "title": "Treatment of Supine Hypertension in Autonomic Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Clonidine", "type": "DRUG" }, { "name": "Nitroglycerin transdermal", "type": "DRUG" }, { "name": "Dipyridamole/ Aspirin (Aggrenox)", "type": "DRUG" }, { "name": "Desmopressin (DDAVP)", "type": "DRUG" }, { "name": "Sildenafil", "type": "DRUG" }, { "name": "Nifedipine", "type": "DRUG" }, { "name": "Hydralazine", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Bosentan", "type": "DRUG" }, { "name": "Diltiazem", "type": "DRUG" }, { "name": "Eplerenone", "type": "DRUG" }, { "name": "guanfacine", "type": "DRUG" }, { "name": "L-arginine", "type": "DIETARY_SUPPLEMENT" }, { "name": "captopril", "type": "DRUG" }, { "name": "carbidopa", "type": "DRUG" }, { "name": "losartan", "type": "DRUG" }, { "name": "metoprolol tartrate", "type": "DRUG" }, { "name": "nebivolol hydrochloride", "type": "DRUG" }, { "name": "prazosin hydrochloride", "type": "DRUG" }, { "name": "tamsulosin hydrochloride", "type": "DRUG" }, { "name": "Head-up tilt.", "type": "OTHER" }, { "name": "aliskiren", "type": "DRUG" }, { "name": "Local heat stress", "type": "OTHER" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 152, "start_date": "2001-01", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2017-10-13", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00223717" }, { "nct_id": "NCT07596914", "title": "Multi-site Feasibility of an Integrated Treatment for the Biology and Experience of Depression: The MULTIBED Study", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Cognitive Behavioral Therapy (CBT)", "type": "BEHAVIORAL" }, { "name": "Whole-Body Hyperthermia", "type": "DEVICE" } ], "intervention_types": [ "BEHAVIORAL", "DEVICE" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2026-08-01", "completion_date": "2029-03-31", "has_results": false, "last_update_posted_date": "2026-05-19", "last_synced_at": "2026-09-03T04:49:21.502Z", "location_count": 3, "location_summary": "San Francisco, California • Boston, Massachusetts • Cleveland, Ohio", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT07596914" } ] }