{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=active+supplement&page=14",
    "query": {
      "intervention": "active supplement",
      "page": 14
    },
    "page_size": 10
  },
  "pagination": {
    "page": 14,
    "page_size": 10,
    "total_count": 509,
    "total_pages": 51,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=active+supplement&page=15&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=active+supplement&page=13&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-19T04:28:29.432Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06384586",
      "title": "Investigation of Dietary Supplement Liquid Shot Products on Mental Energy, Cognition (Acuity),and Mood",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognition",
        "Mental Fatigue",
        "Mood"
      ],
      "interventions": [
        {
          "name": "Placebo shot",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Functional energy shot",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The Water Street Collective",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 45,
      "start_date": "2022-11-17",
      "completion_date": "2022-12-22",
      "has_results": false,
      "last_update_posted_date": "2024-04-25",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "Iselin, New Jersey",
      "locations": [
        {
          "city": "Iselin",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06384586"
    },
    {
      "nct_id": "NCT00798408",
      "title": "The Body's Response to Food Intake in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Elderly"
      ],
      "interventions": [
        {
          "name": "Fluid Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Solid Supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2006-02",
      "completion_date": "2008-01",
      "has_results": false,
      "last_update_posted_date": "2013-09-24",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00798408"
    },
    {
      "nct_id": "NCT03349697",
      "title": "Phyllantus Amarus for the Protection of Liver Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Phyllantus amarus",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Biotropics Malaysia Berhad",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 15,
      "start_date": "2010-07-13",
      "completion_date": "2010-10-16",
      "has_results": false,
      "last_update_posted_date": "2017-11-27",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "Northridge, California",
      "locations": [
        {
          "city": "Northridge",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03349697"
    },
    {
      "nct_id": "NCT03019523",
      "title": "The Effect of a Caffeine Blend on Reaction Time, Mental Performance and Focus in Athletic Males",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mental Fatigue"
      ],
      "interventions": [
        {
          "name": "Caffeine Blend",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Sugar Pill",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of Mary Hardin-Baylor",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "MALE",
        "summary": "18 Years to 25 Years · Male only"
      },
      "enrollment_count": 31,
      "start_date": "2016-08",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2017-01-25",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "Belton, Texas",
      "locations": [
        {
          "city": "Belton",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03019523"
    },
    {
      "nct_id": "NCT05367596",
      "title": "OPTIMIzing muScle Preservation in paTients wIth Cirrhosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Compensated Cirrhosis",
        "Sarcopenia"
      ],
      "interventions": [
        {
          "name": "Continuous Energy Restriction (CER)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Alternate Day Modified Fasting (ADMF)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Group Health Education Sessions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Late Evening Snack",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physical activity",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-monitoring",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Remotely Supervised Exercise Sessions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2022-06-22",
      "completion_date": "2022-12-16",
      "has_results": false,
      "last_update_posted_date": "2023-02-09",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05367596"
    },
    {
      "nct_id": "NCT04829617",
      "title": "Promoting Well-being and Health in Heart Failure",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure",
        "Heart Failure NYHA Class I",
        "Heart Failure NYHA Class II",
        "Heart Failure NYHA Class III"
      ],
      "interventions": [
        {
          "name": "PP-MI Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "MI-alone Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 280,
      "start_date": "2021-11-29",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04829617"
    },
    {
      "nct_id": "NCT05498818",
      "title": "The Effects of Synaquell on Brain Function of Ice Hockey Players",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Synaquell",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "13 Years to 19 Years"
      },
      "enrollment_count": 81,
      "start_date": "2022-11-03",
      "completion_date": "2023-03-14",
      "has_results": false,
      "last_update_posted_date": "2024-01-09",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05498818"
    },
    {
      "nct_id": "NCT05601635",
      "title": "ButyraGen™, Short Chain Fatty Acids and Gut Microbiome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "ButyraGen™",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Clinical Nutrition Research Center, Illinois Institute of Technology",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2022-10-19",
      "completion_date": "2023-01-11",
      "has_results": false,
      "last_update_posted_date": "2023-05-25",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05601635"
    },
    {
      "nct_id": "NCT03074643",
      "title": "Utilizing Protein During Weight Loss to Impact Physical Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Weight Loss",
        "Diet Modification",
        "Aging",
        "Weight Change, Body",
        "Dietary Habits"
      ],
      "interventions": [
        {
          "name": "Weight loss intervention months 0-6",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise intervention months 0-6",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Carbohydrate supplement for months 0-6",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Protein supplement for months 0-6",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Protein supplement for follow-up months 7-18",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 187,
      "start_date": "2017-05-03",
      "completion_date": "2022-04-28",
      "has_results": true,
      "last_update_posted_date": "2023-05-22",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03074643"
    },
    {
      "nct_id": "NCT02776553",
      "title": "A Physical Activity Program in End-state Liver Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End-stage Liver Disease (ESLD)",
        "Liver Transplant",
        "Sarcopenia",
        "Poor Physical Fitness",
        "Cirrhosis",
        "Portal Hypertension"
      ],
      "interventions": [
        {
          "name": "Nutritional consultation",
          "type": "OTHER"
        },
        {
          "name": "Physical training program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral modification therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2016-06",
      "completion_date": "2020-06",
      "has_results": true,
      "last_update_posted_date": "2020-08-06",
      "last_synced_at": "2026-10-19T04:28:29.432Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02776553"
    }
  ]
}