{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=active+supplement&page=2",
    "query": {
      "intervention": "active supplement",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=active+supplement&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T03:16:37.956Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02589600",
      "title": "Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Osteoporotic Fractures",
        "Osteoporosis, Postmenopausal"
      ],
      "interventions": [
        {
          "name": "Zoledronic acid",
          "type": "DRUG"
        },
        {
          "name": "vitamin D",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "calcium",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Susan L. Greenspan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "65 Years and older · Female only"
      },
      "enrollment_count": 310,
      "start_date": "2016-01",
      "completion_date": "2022-06-22",
      "has_results": true,
      "last_update_posted_date": "2023-09-26",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 1,
      "location_summary": "New Kensington, Pennsylvania",
      "locations": [
        {
          "city": "New Kensington",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02589600"
    },
    {
      "nct_id": "NCT05959057",
      "title": "ERr 731® Formulation Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menopause"
      ],
      "interventions": [
        {
          "name": "ERr 731 - Micro-coated",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "ERr 731 - Enteric coated",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Metagenics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 64 Years · Female only"
      },
      "enrollment_count": 15,
      "start_date": "2023-05-24",
      "completion_date": "2023-08-18",
      "has_results": false,
      "last_update_posted_date": "2023-10-30",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 1,
      "location_summary": "Gig Harbor, Washington",
      "locations": [
        {
          "city": "Gig Harbor",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05959057"
    },
    {
      "nct_id": "NCT07220694",
      "title": "Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairment and Insulin Resistance",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insulin Resistance",
        "Mild Cognitive Impairment",
        "Cognitive Decline",
        "Neurodegenerative Disorders"
      ],
      "interventions": [
        {
          "name": "Sabroxy®",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "SF Research Institute, Inc.",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 140,
      "start_date": "2026-01-29",
      "completion_date": "2026-04-29",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07220694"
    },
    {
      "nct_id": "NCT06434181",
      "title": "Beetroot Juice for Boosting Immunity During a Time of Stress.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Beetroot Juice",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Control",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Baylor University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 114,
      "start_date": "2022-04-11",
      "completion_date": "2022-12-13",
      "has_results": false,
      "last_update_posted_date": "2024-05-30",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 2,
      "location_summary": "Dallas, Texas • Waco, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Waco",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06434181"
    },
    {
      "nct_id": "NCT05864521",
      "title": "Beetroot Juice and Sleep",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Active Beetroot Juice Supplement (aBRJ)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Beetroot Juice Supplement (pBRJ)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-09-28",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2025-09-25",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05864521"
    },
    {
      "nct_id": "NCT05450900",
      "title": "Can Biotin Supplementation be Used to Mask hCG Abuse?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Choriogonadotropin Alpha",
          "type": "DRUG"
        },
        {
          "name": "biotin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Microcellulose filler",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Sports Medicine Research and Testing Laboratory",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "18 Years to 55 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2022-10-27",
      "completion_date": "2023-02-02",
      "has_results": false,
      "last_update_posted_date": "2023-02-03",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05450900"
    },
    {
      "nct_id": "NCT00915200",
      "title": "N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Nephropathies",
        "Proteinuria",
        "Oxidative Stress"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "silibin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "high-dose silibin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "N-acetylcysteine placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "silibin placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 114,
      "start_date": "2009-10",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-06-27",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00915200"
    },
    {
      "nct_id": "NCT03226106",
      "title": "Optimizing Physical Activity Outcomes After Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty",
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Physical Activity Behavior Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 114,
      "start_date": "2017-11-15",
      "completion_date": "2023-05-15",
      "has_results": true,
      "last_update_posted_date": "2024-10-16",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03226106"
    },
    {
      "nct_id": "NCT04045288",
      "title": "SWITCH Implementation Effectiveness Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sedentary Behavior",
        "Health Promotion",
        "Overweight and Obesity",
        "Healthy Lifestyle",
        "Diet, Healthy"
      ],
      "interventions": [
        {
          "name": "Standard Implementation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Implementation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Iowa State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "9 Years to 11 Years"
      },
      "enrollment_count": 1984,
      "start_date": "2017-08-15",
      "completion_date": "2018-05-15",
      "has_results": false,
      "last_update_posted_date": "2019-08-05",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 1,
      "location_summary": "Ames, Iowa",
      "locations": [
        {
          "city": "Ames",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04045288"
    },
    {
      "nct_id": "NCT05175248",
      "title": "Nutritional Intervention for Endometriosis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endometriosis"
      ],
      "interventions": [
        {
          "name": "Plant-based Intervention Group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Physicians Committee for Responsible Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2022-03-02",
      "completion_date": "2029-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-09-04T03:16:37.956Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05175248"
    }
  ]
}